Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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Products
- STAT5-IN-2◐ .Made to order · 8–12 wks Item #: S649601View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1-[2-(1H-indol-5-yloxy)ethyl]-4,4-dimethyl-6-pyridin-3-yl-2,3-dihydroquinoline
- SMILES
- CC1(CCN(C2=C1C=C(C=C2)C3=CN=CC=C3)CCOC4=CC5=C(C=C4)NC=C5)C
- InChIKey
- BELIZDRKUICBJC-UHFFFAOYSA-N
- InChI
- 1S/C26H27N3O/c1-26(2)10-13-29(14-15-30-22-6-7-24-20(16-22)9-12-28-24)25-8-5-19(17-23(25)26)21-4-3-11-27-18-21/h3-9,11-12,16-18,28H,10,13-15H2,1-2H3
- STAT3-IN-3CAS: 2361304-26-7 Formula: C27H26BrN3O6S Molecular Weight: 600.48◐ .Made to order · 8–12 wks Item #: S649834View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- BrC1=C2C(S(C(C(N3CCN(C(C4=CC5=CC=C(N(CC)CC)C=C5OC4=O)=O)CC3)=O)=C2)(=O)=O)=CC=C1
- Isolinderalactone◐ .Made to order · 8–12 wks Item #: I649854View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3aS,4R,8bR)-4-ethenyl-4,8-dimethyl-3-methylidene-5,8b-dihydro-3aH-furo[2,3-e][1]benzofuran-2-one
- SMILES
- CC1=COC2=C1C3C(C(=C)C(=O)O3)C(C2)(C)C=C
- InChIKey
- VXZIFOKTSURLNL-YDHLFZDLSA-N
- InChI
- 1S/C15H16O3/c1-5-15(4)6-10-11(8(2)7-17-10)13-12(15)9(3)14(16)18-13/h5,7,12-13H,1,3,6H2,2,4H3/t12-,13-,15-/m0/s1
- Tyk2-IN-5◐ .Made to order · 8–12 wks Item #: T649821View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(1R,2S)-2-fluorocyclopropyl]-8-(methylamino)-6-[(2-oxo-1-pyridin-2-ylpyridin-3-yl)amino]imidazo[1,2-b]pyridazine-3-carboxamide
- SMILES
- CNC1=CC(=NN2C1=NC=C2C(=O)NC3CC3F)NC4=CC=CN(C4=O)C5=CC=CC=N5
- InChIKey
- YITUGUNLCGLOII-GXTWGEPZSA-N
- InChI
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- AngolineCAS: 21080-31-9 Formula: C22H21NO5 Molecular Weight: 379.41Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: A649791View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 1,2,13-trimethoxy-12-methyl-13H-[1,3]benzodioxolo[5,6-c]phenanthridine
- SMILES
- CN1C(C2=C(C=CC(=C2OC)OC)C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC
- InChIKey
- LVWAKZBZWYHYCJ-UHFFFAOYSA-N
- InChI
- 1S/C22H21NO5/c1-23-20-14(6-5-12-9-17-18(10-15(12)20)28-11-27-17)13-7-8-16(24-2)21(25-3)19(13)22(23)26-4/h5-10,22H,11H2,1-4H3
- Synonyms
- HY-N7674 | ( inverted exclamation markA)-Angoline | SureCN13103356 | DTXSID90943391 | AKOS040763668 | C09336 | SCHEMB...
- DanvatirsenCAS: 1402357-06-5 Molecular Weight: 5422.00◐ .Made to order · 8–12 wks Item #: D649973View ProductPricing & Pack Sizes
Technical Identifiers
- Ilginatinib maleate◐ .Made to order · 8–12 wks Item #: I649955View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-but-2-enedioic acid;6-N-[(1S)-1-(4-fluorophenyl)ethyl]-4-(1-methylpyrazol-4-yl)-2-N-pyrazin-2-ylpyridine-2,6-diamine
- SMILES
- CC(C1=CC=C(C=C1)F)NC2=CC(=CC(=N2)NC3=NC=CN=C3)C4=CN(N=C4)C.C(=CC(=O)O)C(=O)O
- InChIKey
- OVAGJAAQMBYZDS-FXSDFHGDSA-N
- InChI
- show more
- Synonyms
- AKOS040733881 | NS-018 maleateNS-018 maleate | NS-018 maleate | HY-19631 | Ilginatinib (maleate) | 2,6-Pyridinediamin...
- Tofacitinib-d3citrateCAS: 2701680-77-3 Formula: C22H25D3N6O8 Molecular Weight: 507.51◐ .Made to order · 8–12 wks Item #: T650168View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(CC#N)N1C[C@H](N(C2=C3C(NC=C3)=NC=N2)C([2H])([2H])[2H])[C@H](C)CC1.O=C(CC(C(O)=O)(O)CC(O)=O)O
- HTH-01-091CAS: 2000209-42-5 Formula: C26H28Cl2N4O2 Molecular Weight: 499.43◐ .Made to order · 8–12 wks Item #: H650200View ProductPricing & Pack Sizes
Technical Identifiers
- CK2/ERK8-IN-1◐ .Made to order · 8–12 wks Item #: C650431View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazol-1-yl]acetic acid
- SMILES
- CN(C)C1=NC2=C(N1CC(=O)O)C(=C(C(=C2Br)Br)Br)Br
- InChIKey
- PHAOTASRLQMKBE-UHFFFAOYSA-N
- InChI
- 1S/C11H9Br4N3O2/c1-17(2)11-16-9-7(14)5(12)6(13)8(15)10(9)18(11)3-4(19)20/h3H2,1-2H3,(H,19,20)
- Synonyms
- GTPL8140 | TMCB | CK2/ERK8-IN-1 | Casein Kinase II Inhibitor VI | 2-[4,5,6,7-tetrabromo-2-(dimethylamino)benzimidazol...
- Avitinib maleateCAS: 1557268-88-8 Formula: C30H30FN7O6 Molecular Weight: 603.60◐ .Made to order · 8–12 wks Item #: A650397View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-but-2-enedioic acid;N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=C(C=C(C=C2)NC3=NC4=C(C=CN4)C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)F.C(=CC(=O)O)C(=O)O
- InChIKey
- VRHPZWLHPIENFW-BTJKTKAUSA-N
- InChI
- show more
- Synonyms
- Abivertinib maleate anhydrous | A901932 | HY-19816A | 2-Propenamide, N-[3-[[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)ph...
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Technical Details Quality & specification info on every product page
Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].