Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- MS9427CAS: 2772613-37-1 Formula: C48H58ClFN8O12 Molecular Weight: 993.47◐ .Made to order · 8–12 wks Item #: M650356View ProductPricing & Pack Sizes
Technical Identifiers
- Osimertinib dimesylate◐ .Made to order · 8–12 wks Item #: O650598View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid
- SMILES
- CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O.CS(=O)(=O)O
- InChIKey
- RPUCCTLBBCSFEX-UHFFFAOYSA-N
- InChI
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- Rezivertinib◐ .Made to order · 8–12 wks Item #: R650600View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[2-(dimethylamino)ethoxy]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
- SMILES
- CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=CC(=C(C=C4OC)OCCN(C)C)NC(=O)C=C
- InChIKey
- BPMZUKYFIDPLEA-UHFFFAOYSA-N
- InChI
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- Synonyms
- 2-Propenamide, N-(2-(2-(dimethylamino)ethoxy)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl)amino)phenyl)- |...
- C188CAS: 823828-18-8 Formula: C19H15NO7S2 Molecular Weight: 433.45◐ .Made to order · 8–12 wks Item #: C650844View ProductPricing & Pack Sizes
Technical Identifiers
- Almonertinib hydrochloride◐ .Made to order · 8–12 wks Item #: A650866View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-[[4-(1-cyclopropylindol-3-yl)pyrimidin-2-yl]amino]-2-[2-(dimethylamino)ethyl-methylamino]-4-methoxyphenyl]prop-2-enamide;hydrochloride
- SMILES
- CN(C)CCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C5CC5)OC.Cl
- InChIKey
- CUXBWKDZKQGJNN-UHFFFAOYSA-N
- InChI
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- Salviolone◐ .Made to order · 8–12 wks Item #: S651322View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 9-hydroxy-4,4,8-trimethyl-2,3-dihydro-1H-cyclohepta[a]naphthalen-10-one
- SMILES
- CC1=C(C(=O)C=C2C3=C(C=CC2=C1)C(CCC3)(C)C)O
- InChIKey
- QATRODNHXVHGNU-UHFFFAOYSA-N
- InChI
- 1S/C18H20O2/c1-11-9-12-6-7-15-13(5-4-8-18(15,2)3)14(12)10-16(19)17(11)20/h6-7,9-10H,4-5,8H2,1-3H3,(H,19,20)
- limertinibCAS: 1934259-00-3 Formula: C29H32ClN7O2 Molecular Weight: 546.06◐ .Made to order · 8–12 wks Item #: L651246View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(NC1=CC(NC2=NC=C(C(NC3=CC4=C(C=CC=C4)C=C3)=N2)Cl)=C(C=C1N(CCN(C)C)C)OC)C=C
- AC-4-130◐ .Made to order · 8–12 wks Item #: A651226View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[[2-[(4-chlorophenyl)methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]-[(3,5-ditert-butylphenyl)methyl]amino]benzoic acid
- SMILES
- CC(C)(C)C1=CC(=CC(=C1)CN(C2=CC=C(C=C2)C(=O)O)C(=O)CN(CC3=CC=C(C=C3)Cl)S(=O)(=O)C4=C(C(=C(C(=C4F)F)F)F)F)C(C)(C)C
- InChIKey
- NMQUSJQZQWKQBL-UHFFFAOYSA-N
- InChI
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- CCT365623 hydrochloride◐ .Made to order · 8–12 wks Item #: C651445View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [5-(3-methylsulfonyl-5-phenylphenyl)sulfonylthiophen-2-yl]methanamine;hydrochloride
- SMILES
- CS(=O)(=O)C1=CC(=CC(=C1)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(S3)CN.Cl
- InChIKey
- MKBRQENFVVWIGU-UHFFFAOYSA-N
- InChI
- 1S/C18H17NO4S3.ClH/c1-25(20,21)16-9-14(13-5-3-2-4-6-13)10-17(11-16)26(22,23)18-8-7-15(12-19)24-18;/h2-11H,12,19H2,1H3;1H
- ZasocitinibCAS: 2272904-53-5 EC Number: 960-464-3 PubChem CID: 137441492 Formula: C23H24N8O3 Molecular Weight: 460.49◐ .Made to order · 8–12 wks Item #: Z651589View ProductPricing & Pack Sizes
Technical Identifiers
- JAK2/FLT3-IN-1CAS: 2387765-27-5 Formula: C25H34FN7O Molecular Weight: 467.58◐ .Made to order · 8–12 wks Item #: J651882View ProductPricing & Pack Sizes
Technical Identifiers
- LorpucitinibCAS: 2230282-02-5 Formula: C22H28N6O2 Molecular Weight: 408.50◐ .Made to order · 8–12 wks Item #: L651770View ProductPricing & Pack Sizes
Technical Identifiers
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].