Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- EGFR-IN-11CAS: 2463200-44-2 Formula: C29H35N9O2S Molecular Weight: 573.71◐ .Made to order · 8–12 wks Item #: E647319View ProductPricing & Pack Sizes
Technical Identifiers
- UC-514321◐ .Made to order · 8–12 wks Item #: U647255View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[(3,5-ditert-butyl-4-hydroxyphenyl)-morpholin-4-ylmethyl]-1,3-benzodioxol-5-ol
- SMILES
- CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)C(C2=CC3=C(C=C2O)OCO3)N4CCOCC4
- InChIKey
- XNARHFDDQALZPZ-UHFFFAOYSA-N
- InChI
- 1S/C26H35NO5/c1-25(2,3)18-11-16(12-19(24(18)29)26(4,5)6)23(27-7-9-30-10-8-27)17-13-21-22(14-20(17)28)32-15-31-21/h11-14,23,28-29H,7-10,15H2,1-6H3
- AV-412CAS: 451493-31-5 Formula: C41H44ClFN6O7S2 Molecular Weight: 851.41Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: A647278View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- MP412 | N-(4-((3-Chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acr...
- Neratinib-d6CAS: 1259519-18-0 Formula: C30H23D6ClN6O3 Molecular Weight: 563.08◐ .Made to order · 8–12 wks Item #: N647202View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-4-[bis(trideuteriomethyl)amino]-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]but-2-enamide
- SMILES
- CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C
- InChIKey
- JWNPDZNEKVCWMY-CJSPGLJTSA-N
- InChI
- show more
- SI-109CAS: 2429877-30-3 Formula: C40H44F2N7O9P Molecular Weight: 835.79◐ .Made to order · 8–12 wks Item #: S647472View ProductPricing & Pack Sizes
Technical Identifiers
- Icotinib Hydrochloride◐ .Made to order · 8–12 wks Item #: I647508View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine;hydrochloride
- SMILES
- C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl
- InChIKey
- PNNGXMJMUUJHAV-UHFFFAOYSA-N
- InChI
- 1S/C22H21N3O4.ClH/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20;/h1,3-5,12-15H,6-11H2,(H,23,24,25);1H
- Synonyms
- F84862 | Icotinib Hydrochloride | AKOS026750418 | ICOTINIB HYDROCHLORIDE [WHO-DD] | N-(3-Ethynylphenyl)-7,8,10,11,13,...
- DBPR112Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: D647633View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-4-(dimethylamino)-N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]but-2-enamide
- SMILES
- CN(C)CC=CC(=O)NC1=CC=CC(=C1)C2=C(OC3=NC=NC(=C23)NC(CO)C4=CC=CC=C4)C5=CC=CC=C5
- InChIKey
- NQAMTZUVRFRJCZ-VMMYIZNOSA-N
- InChI
- show more
- Synonyms
- (S,E)-4-(Dimethylamino)-N-(3-(4-((2-hydroxy-1-phenylethyl)amino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)but-2-enamide
- MogrolCAS: 88930-15-8 Formula: C30H52O4 Molecular Weight: 476.73Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: M647596View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- (3β,9β,10α,11α,24R)-9-Methyl-19-norlanost-5-ene-3,11,24,25-tetrol | (3S,8S,9R,10R,11R,13R,14S,17R)-17-((2R,5R)-5,6-Di...
- Povorcitinib phosphate◐ .Made to order · 8–12 wks Item #: P647619View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- CC1=C(C(=NN1)C)C2=CN(N=C2)C3(CN(C3)C4=C(C=C(C(=C4)F)C(=O)N[C@@H](C)C(F)(F)F)F)CC#N.OP(=O)(O)O
- Tyrphostin A51◐ .Made to order · 8–12 wks Item #: T647763View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3Z)-2-amino-4-(3,4,5-trihydroxyphenyl)buta-1,3-diene-1,1,3-tricarbonitrile
- SMILES
- C1=C(C=C(C(=C1O)O)O)C=C(C#N)C(=C(C#N)C#N)N
- InChIKey
- JKNOYWVMHPMBEL-UNXLUWIOSA-N
- InChI
- 1S/C13H8N4O3/c14-4-8(12(17)9(5-15)6-16)1-7-2-10(18)13(20)11(19)3-7/h1-3,18-20H,17H2/b8-1+
- Synonyms
- DTXSID501017104 | 2-Amino-1,1,3-tricyano-4-[3',4',5'-trihydroxyphenyl]butadiene | MLS002153329 | 2-amino-7-phosphonoh...
- ButyzamideCAS: 1110767-45-7 Formula: C29H32Cl2N2O5S Molecular Weight: 591.55◐ .Made to order · 8–12 wks Item #: B648013View ProductPricing & Pack Sizes
Technical Identifiers
- β-Hydroxyisovalerylshikonin◐ .Made to order · 8–12 wks Item #: H648056View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- [1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] 3-hydroxy-3-methylbutanoate
- SMILES
- CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)CC(C)(C)O)C
- InChIKey
- MXANJRGHSFELEJ-UHFFFAOYSA-N
- InChI
- 1S/C21H24O7/c1-11(2)5-8-16(28-17(25)10-21(3,4)27)12-9-15(24)18-13(22)6-7-14(23)19(18)20(12)26/h5-7,9,16,22-23,27H,8,10H2,1-4H3
- Synonyms
- 3'-Hydroxyisovalerylshikonin; (c)micro-Hydroxyisovalerylshikonin | InChI=1/C21H24O7/c1-11(2)5-8-16(28-17(25)10-21(3,4...
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].