Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- AV 412CAS: 451492-95-8 Formula: C27H28ClFN6O Molecular Weight: 507Solid ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: A288169View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-(3-chloro-4-fluoroanilino)-7-[3-methyl-3-(4-methylpiperazin-1-yl)but-1-ynyl]quinazolin-6-yl]prop-2-enamide
- SMILES
- CC(C)(C#CC1=CC2=C(C=C1NC(=O)C=C)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)N4CCN(CC4)C
- InChIKey
- ZAJXXUDARPGGOC-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- MLS001204877 | NCGC00263195-04 | HMS3244M16 | SMR001224381 | 2-Propenamide, N-(4-((3-chloro-4-fluorophenyl)amino)-7-(...
- AZ 960, Inhibitor of Janus kinase 2CAS: 905586-69-8 Formula: C18H16F2N6 Molecular Weight: 354.36Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A129464View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-fluoro-2-[[(1S)-1-(4-fluorophenyl)ethyl]amino]-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyridine-3-carbonitrile
- SMILES
- CC1=CC(=NN1)NC2=C(C=C(C(=N2)NC(C)C3=CC=C(C=C3)F)C#N)F
- InChIKey
- SUNXHXDJOIXABJ-NSHDSACASA-N
- InChI
- 1S/C18H16F2N6/c1-10-7-16(26-25-10)23-18-15(20)8-13(9-21)17(24-18)22-11(2)12-3-5-14(19)6-4-12/h3-8,11H,1-2H3,(H3,22,23,24,25,26)/t11-/m0/s1
- Synonyms
- (S)-5-fluoro-2-((1-(4-fluorophenyl)ethyl)amino)-6-((5-methyl-1H-pyrazol-3-yl)amino)nicotinonitrile | NCGC00346581-01 ...
- AZD1208, Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene; serine/threonine kinaseCAS: 1204144-28-4 Formula: C21H21N3O2S Molecular Weight: 379.48Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A127698View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (5Z)-5-[[2-[(3R)-3-aminopiperidin-1-yl]-3-phenylphenyl]methylidene]-1,3-thiazolidine-2,4-dione
- SMILES
- C1CC(CN(C1)C2=C(C=CC=C2C3=CC=CC=C3)C=C4C(=O)NC(=O)S4)N
- InChIKey
- MCUJKPPARUPFJM-UWCCDQBKSA-N
- InChI
- show more
- Synonyms
- AZD 1208 [WHO-DD] | Q27074698 | FT-0633869 | J-013789 | HY-15604 | S98NFM1378 | SW219766-1 | 1204144-28-4 | AZ-1208 |...
- AZD-9291 mesylate, Epidermal growth factor receptor erbB1 inhibitor● In Stock — US warehouse, ships to EU* Item #: A302850View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide;methanesulfonic acid
- SMILES
- CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC.CS(=O)(=O)O
- InChIKey
- FUKSNUHSJBTCFJ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-[2-[[2-(Dimethylamino)ethyl]methylamino]-4-methoxy-5-[[4-(1-methyl-1H-indol-3-yl)-2-pyrimidinyl]amino]phenyl]-2-pro...
- Osimertinib (AZD9291), Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: A302849View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide
- SMILES
- CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
- InChIKey
- DUYJMQONPNNFPI-UHFFFAOYSA-N
- InChI
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- Synonyms
- Mereletinib | AZD-9291
- TCS 21311Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: T287291View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[5-[4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
- SMILES
- CC(C)(C(=O)N1CCN(CC1)C2=CC(=C(C=C2)C(F)(F)F)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54)O
- InChIKey
- CLGRAWDGLMENOD-UHFFFAOYSA-N
- InChI
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- Synonyms
- NIBR3049 | NIBR-3049 | J-005320 | 3-[5-[4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl]-2-(trifluoromethyl)phenyl]-4-(...
- AG 555 (Tyrphostin B46)CAS: 133550-34-2 Formula: C19H18N2O3 Molecular Weight: 322.36● In Stock — US warehouse, ships to EU* Item #: A275199View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)prop-2-enamide
- SMILES
- C1=CC=C(C=C1)CCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
- InChIKey
- GSQOBTOAOGXIFL-LFIBNONCSA-N
- InChI
- 1S/C19H18N2O3/c20-13-16(11-15-8-9-17(22)18(23)12-15)19(24)21-10-4-7-14-5-2-1-3-6-14/h1-3,5-6,8-9,11-12,22-23H,4,7,10H2,(H,21,24)/b16-11+
- Synonyms
- NCGC00016028-05 | Tyrphostin deriv. 46 | J-006402 | 2-Propenamide,2-cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-...
- AG 556CAS: 133550-41-1 Formula: C20H20N2O3 Molecular Weight: 336.39● In Stock — US warehouse, ships to EU* Item #: A341248View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)prop-2-enamide
- SMILES
- C1=CC=C(C=C1)CCCCNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
- InChIKey
- GWCNJMUSWLTSCW-SFQUDFHCSA-N
- InChI
- 1S/C20H20N2O3/c21-14-17(12-16-9-10-18(23)19(24)13-16)20(25)22-11-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,23-24H,4-5,8,11H2,(H,22,25)/b17-12+
- Synonyms
- SR-01000597669-2 | Tyrphostin AG556 | 2-Propenamide, 2-cyano-3-(3,4-dihydroxyphenyl)-N-(4-phenylbutyl)- | SCHEMBL1873...
- Dacomitinib (PF299804, PF299), Receptor protein-tyrosine kinase erbB-4 inhibitorCAS: 1110813-31-4 Formula: C24H25ClFN5O2 Molecular Weight: 469.94● In Stock — US warehouse, ships to EU* Item #: D129347View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4
- InChIKey
- LVXJQMNHJWSHET-AATRIKPKSA-N
- InChI
- show more
- Synonyms
- PF299804 | PF299 | AM83538 | dacomitinibum | Q17130597 | MLS006011275 | (2E)-N-(4-((3-CHLORO-4-FLUOROPHENYL)AMINO)-7-...
- Mubritinib (TAK 165), Receptor protein-tyrosine kinase erbB-2 inhibitorCAS: 366017-09-6 Formula: C25H23F3N4O2 Molecular Weight: 468.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: M129797View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[[4-[4-(triazol-1-yl)butyl]phenoxy]methyl]-2-[(E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1,3-oxazole
- SMILES
- C1=CC(=CC=C1CCCCN2C=CN=N2)OCC3=COC(=N3)C=CC4=CC=C(C=C4)C(F)(F)F
- InChIKey
- ZTFBIUXIQYRUNT-MDWZMJQESA-N
- InChI
- show more
- Synonyms
- TAK165 | DNDI1268116 | M3058 | SCHEMBL50451 | CCG-269433 | Mubritinib (USAN/INN) | D04025 | DTXSID501026014 | [4-[4-[...
- Flubendazole● In Stock — US warehouse, ships to EU* Item #: F129912View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- methyl N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
- SMILES
- COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=C(C=C3)F
- InChIKey
- CPEUVMUXAHMANV-UHFFFAOYSA-N
- InChI
- 1S/C16H12FN3O3/c1-23-16(22)20-15-18-12-7-4-10(8-13(12)19-15)14(21)9-2-5-11(17)6-3-9/h2-8H,1H3,(H2,18,19,20,22)
- Synonyms
- AB00639981-06 | DB08974 | FLUBENDAZOLE [USAN] | HMS2090I16 | MLS006010905 | DTXSID8023058 | Flubendazol [INN-Spanish]...
- MyristicinAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.● In Stock — US warehouse, ships to EU* Item #: M136675View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-methoxy-6-prop-2-enyl-1,3-benzodioxole
- SMILES
- COC1=CC(=CC2=C1OCO2)CC=C
- InChIKey
- BNWJOHGLIBDBOB-UHFFFAOYSA-N
- InChI
- 1S/C11H12O3/c1-3-4-8-5-9(12-2)11-10(6-8)13-7-14-11/h3,5-6H,1,4,7H2,2H3
- Synonyms
- CAS-607-91-0 | 4-Methoxy-6-[2-propenyl]-1,3-benzodioxole | HY-N2510 | NCGC00257726-01 | STK693140 | 04PD6CT78W | 1-Me...
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].