Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- Tyrphostin RG 14620● In Stock — US warehouse, ships to EU* Item #: T337827View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile
- SMILES
- C1=CC(=CN=C1)C(=CC2=CC(=CC(=C2)Cl)Cl)C#N
- InChIKey
- TYXIVBJQPBWBHO-QCDXTXTGSA-N
- InChI
- 1S/C14H8Cl2N2/c15-13-5-10(6-14(16)7-13)4-12(8-17)11-2-1-3-18-9-11/h1-7,9H/b12-4-
- Synonyms
- (E)-3-(3,5-dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile | MFCD00236445 | (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylpr...
- DiosgenineSolid ≥90%● In Stock — US warehouse, ships to EU* Item #: D101264View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol
- SMILES
- CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1
- InChIKey
- WQLVFSAGQJTQCK-VKROHFNGSA-N
- InChI
- show more
- Synonyms
- (3beta,25R)-spirost-5-en-3-ol | AKOS015961083 | DIOSGENIN | (25R)-5-Spirosten-3A-ol | K49P2K8WLX | MFCD00016887 | DIO...
- IcaritinCAS: 118525-40-9 Formula: C21H20O6 Molecular Weight: 368.38Solid ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: I137443View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one
- SMILES
- CC(=CCC1=C2C(=C(C=C1O)O)C(=O)C(=C(O2)C3=CC=C(C=C3)OC)O)C
- InChIKey
- TUUXBSASAQJECY-UHFFFAOYSA-N
- InChI
- 1S/C21H20O6/c1-11(2)4-9-14-15(22)10-16(23)17-18(24)19(25)20(27-21(14)17)12-5-7-13(26-3)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
- Synonyms
- Icaritin | 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methylbut-2-enyl)chromen-4-one | UFE666UELY | CHEMBL498485 | SGN...
- Upadacitinib (ABT-494), Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3;Inhibitor of tyrosine kinase 2Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: U302354View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3S,4R)-3-ethyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide
- SMILES
- CCC1CN(CC1C2=CN=C3N2C4=C(NC=C4)N=C3)C(=O)NCC(F)(F)F
- InChIKey
- WYQFJHHDOKWSHR-MNOVXSKESA-N
- InChI
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- Synonyms
- ABT-494 | (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carbo...
- Pyridone 6, Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3;Inhibitor of tyrosine kinase 2Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● In Stock — US warehouse, ships to EU* Item #: P287366View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-tert-butyl-15-fluoro-3,5,10-triazatetracyclo[11.4.0.02,6.07,12]heptadeca-1(13),2(6),4,7(12),8,14,16-heptaen-11-one
- SMILES
- CC(C)(C)C1=NC2=C(N1)C3=C(C=C(C=C3)F)C4=C2C=CNC4=O
- InChIKey
- VNDWQCSOSCCWIP-UHFFFAOYSA-N
- InChI
- 1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
- Synonyms
- CHEBI:195037 | DTXSID40420526 | EX-A123 | LDX3F0CCST | SCHEMBL904545 | HMS3244K22 | JAK Inhibitor I; 2-(1,1-Dimethyle...
- EBE-A22CAS: 229476-53-3 Formula: C17H16BrN3O2 Molecular Weight: 374.23● In Stock — US warehouse, ships to EU* Item #: E126691View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-bromophenyl)-6,7-dimethoxy-N-methylquinazolin-4-amine
- SMILES
- CN(C1=CC(=CC=C1)Br)C2=NC=NC3=CC(=C(C=C32)OC)OC
- InChIKey
- IPWGDOZPSOZFOD-UHFFFAOYSA-N
- InChI
- 1S/C17H16BrN3O2/c1-21(12-6-4-5-11(18)7-12)17-13-8-15(22-2)16(23-3)9-14(13)19-10-20-17/h4-10H,1-3H3
- Synonyms
- EBE-A 22;EBE A22; EBEA22 | MS-26039 | N-(3-bromophenyl)-6,7-dimethoxy-N-methylquinazolin-4-amine | s6530 | AKOS030526...
- Icotinib, Epidermal growth factor receptor erbB1 inhibitorCAS: 610798-31-7 Formula: C22H21N3O4 Molecular Weight: 391.42Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: I129405View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine
- SMILES
- C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4
- InChIKey
- QQLKULDARVNMAL-UHFFFAOYSA-N
- InChI
- 1S/C22H21N3O4/c1-2-16-4-3-5-17(12-16)25-22-18-13-20-21(14-19(18)23-15-24-22)29-11-9-27-7-6-26-8-10-28-20/h1,3-5,12-15H,6-11H2,(H,23,24,25)
- Synonyms
- N-(3-ethynylphenyl)-2,5,8,11-tetraoxa-15,17-diazatricyclo[10.8.0.014,19]icosa-1(12),13,15,17,19-pentaen-18-amine | Q1...
- BIBX 1382 dihydrochloride◐ .Made to order · 8–12 wks Item #: B287903View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-N-(3-chloro-4-fluorophenyl)-6-N-(1-methylpiperidin-4-yl)pyrimido[5,4-d]pyrimidine-4,6-diamine;dihydrochloride
- SMILES
- CN1CCC(CC1)NC2=NC=C3C(=N2)C(=NC=N3)NC4=CC(=C(C=C4)F)Cl.Cl.Cl
- InChIKey
- RFXGEKWBTCMDAW-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- EC-000.2387 | N8-(3-Chloro-4-fluorophenyl)-N2-(1-methyl-4-piperidinyl)-pyrimido[5,4-d]pyrimidine-2,8-diamine dihydroc...
- BML-260CAS: 101439-76-3 Formula: C17H11NO3S2 Molecular Weight: 341.4● In Stock — US warehouse, ships to EU* Item #: B333552View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(5-benzylidene-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)benzoic acid
- SMILES
- C1=CC=C(C=C1)C=C2C(=O)N(C(=S)S2)C3=CC=C(C=C3)C(=O)O
- InChIKey
- HJGHAHOKZBWVGK-UHFFFAOYSA-N
- InChI
- 1S/C17H11NO3S2/c19-15-14(10-11-4-2-1-3-5-11)23-17(22)18(15)13-8-6-12(7-9-13)16(20)21/h1-10H,(H,20,21)
- Synonyms
- SCHEMBL6789390 | 4-(5-benzylidene-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl)benzoic acid | 4-(5-Phenylmethylene-4-ox...
- WHI-P180● In Stock — US warehouse, ships to EU* Item #: W336667View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 3-[(6,7-dimethoxyquinazolin-4-yl)amino]phenol
- SMILES
- COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC
- InChIKey
- BNDYIYYKEIXHNK-UHFFFAOYSA-N
- InChI
- 1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10/h3-9,20H,1-2H3,(H,17,18,19)
- Synonyms
- DB03365 | AKOS002350928 | BDBM4622 | WHI-P180(Janex 3) | DTXSID50943478 | s6520 | Phenol, 3-[(6,7-dimethoxy-4-quinazo...
- TAK-285, Epidermal growth factor receptor erbB1 inhibitor● In Stock — US warehouse, ships to EU* Item #: T126234View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[2-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-3-hydroxy-3-methylbutanamide
- SMILES
- CC(C)(CC(=O)NCCN1C=CC2=C1C(=NC=N2)NC3=CC(=C(C=C3)OC4=CC=CC(=C4)C(F)(F)F)Cl)O
- InChIKey
- ZYQXEVJIFYIBHZ-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- CHEBI:102166 | n-{2-[4-({3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl}amino)-5h-pyrrolo[3,2-d]pyrimidin-5-yl]ethyl}-...
- S3I-201● In Stock — US warehouse, ships to EU* Item #: S129625View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-hydroxy-4-[[2-(4-methylphenyl)sulfonyloxyacetyl]amino]benzoic acid
- SMILES
- CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O
- InChIKey
- HWNUSGNZBAISFM-UHFFFAOYSA-N
- InChI
- 1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
- Synonyms
- NSC 74859 | AKOS016366328 | Q-103549 | SCHEMBL4456216 | 2-Hydroxy-4-(((4-methylphenyl)sulfonyloxy)acetyl)amino)-benzo...
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Pack Size Options Multiple packaging sizes with pricing access from listing
R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].