Explore compounds mapped to JAK/STAT signaling for cytokine biology, immune response research, and target validation. This category helps organize pathway modulators used in signaling studies, assay development, and translational discovery.
JAK/STAT Signaling
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- BMS-690514, Receptor protein-tyrosine kinase erbB-4 inhibitorCAS: 859853-30-8 Formula: C19H24N6O2 Molecular Weight: 368.44Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: B127024View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3R,4R)-4-amino-1-[[4-(3-methoxyanilino)pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol
- SMILES
- COC1=CC=CC(=C1)NC2=NC=NN3C2=C(C=C3)CN4CCC(C(C4)O)N
- InChIKey
- CSGQVNMSRKWUSH-IAGOWNOFSA-N
- InChI
- show more
- Synonyms
- (3R,4R)-4-amino-1-((4-(3-methoxyphenylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methyl)piperidin-3-ol | BCP9000434 | (3...
- ARRY-380CAS: 937265-83-3 Formula: C29H27N7O4S Molecular Weight: 569.63● In Stock — US warehouse, ships to EU* Item #: A126334View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine
- SMILES
- CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5
- InChIKey
- QVMNYGOVNWWFKF-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- BCP9000319 | NCGC00346672-01 | 4-quinazolinamine, 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-n-[3-methy...
- Fludarabine, Inhibitor of ribonucleotide reductase catalytic subunit M1;Inhibitor of ribonucleotide reductase regulatory subunit M2Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: F122998View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
- SMILES
- C1=NC2=C(N=C(N=C2N1C3C(C(C(O3)CO)O)O)F)N
- InChIKey
- HBUBKKRHXORPQB-FJFJXFQQSA-N
- InChI
- 1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
- Synonyms
- (2R,3S,4S,5R)-2-(6-azanyl-2-fluoranyl-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol | 9-?-D-Arabinofuranosyl-2-fluoro...
- Baricitinib(INCB028050), Tyrosine-protein kinase JAK2 inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● In Stock — US warehouse, ships to EU* Item #: B127687View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile
- SMILES
- CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
- InChIKey
- XUZMWHLSFXCVMG-UHFFFAOYSA-N
- InChI
- 1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)
- Synonyms
- DB11817 | GTPL7792 | HMS3672M15 | LY3009104 | LY-3009104 | Z2724205326 | 2-[1-ETHYLSULFONYL-3-[4-(7H-PYRROLO[2,3-D]PY...
- ASP3026, ALK tyrosine kinase receptor inhibitorCAS: 1097917-15-1 Formula: C29H40N8O3S Molecular Weight: 580.74Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A128022View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-N-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]-4-N-(2-propan-2-ylsulfonylphenyl)-1,3,5-triazine-2,4-diamine
- SMILES
- CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=N2)NC3=C(C=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)OC
- InChIKey
- MGGBYMDAPCCKCT-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- F6O | SMR004702945 | UNII-HP4L6MXF10 | XTB91715 | NCGC00345791-01 | N2-(2-(isopropylsulfonyl)phenyl)-N4-(2-methoxy-4-...
- AST-1306 TsOHCAS: 1050500-29-2 Formula: C24H18ClFN4O2·C7H8O3S Molecular Weight: 621.08● In Stock — US warehouse, ships to EU* Item #: A129426View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]prop-2-enamide;4-methylbenzenesulfonic acid
- SMILES
- CC1=CC=C(C=C1)S(=O)(=O)O.C=CC(=O)NC1=CC2=C(C=C1)N=CN=C2NC3=CC(=C(C=C3)OCC4=CC(=CC=C4)F)Cl
- InChIKey
- ZMUKJEHWLJBODV-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- HMS3655D08 | J-523338 | AST-1306 (TsOH) | FT-0741105 | N-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-y...
- AZD1480, Tyrosine-protein kinase JAK2 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: A126326View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 5-chloro-2-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
- SMILES
- CC1=CC(=NN1)NC2=NC(=NC=C2Cl)NC(C)C3=NC=C(C=N3)F
- InChIKey
- PDOQBOJDRPLBQU-QMMMGPOBSA-N
- InChI
- 1S/C14H14ClFN8/c1-7-3-11(24-23-7)21-13-10(15)6-19-14(22-13)20-8(2)12-17-4-9(16)5-18-12/h3-6,8H,1-2H3,(H3,19,20,21,22,23,24)/t8-/m0/s1
- Synonyms
- 5-Chloro-N2-[(1S)-1-(5-fluoro-2-pyrimidinyl)ethyl]-N4-(5-methyl-1H-pyrazol-3-yl)-2,4-pyrimidinediamine | 5-Chloro-N2-...
- Atractylenolide IICAS: 73069-14-4 Formula: C15H20O2 Molecular Weight: 232.32● In Stock — US warehouse, ships to EU* Item #: A304498View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (4aS,8aR,9aS)-3,8a-dimethyl-5-methylidene-4a,6,7,8,9,9a-hexahydro-4H-benzo[f][1]benzofuran-2-one
- SMILES
- CC1=C2CC3C(=C)CCCC3(CC2OC1=O)C
- InChIKey
- OQYBLUDOOFOBPO-KCQAQPDRSA-N
- InChI
- 1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h12-13H,1,4-8H2,2-3H3/t12-,13-,15+/m0/s1
- Synonyms
- Asterolide | HY-N0202 | MFCD09037396 | BDBM50241946 | CHEBI:182501 | Atractylenolide II | AS-76824 | C17886 | Q633984...
- DiosgenineAnalytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥95%● In Stock — US warehouse, ships to EU* Item #: D101263View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-ol
- SMILES
- CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CC=C6C5(CCC(C6)O)C)C)C)OC1
- InChIKey
- WQLVFSAGQJTQCK-VKROHFNGSA-N
- InChI
- show more
- Synonyms
- (3beta,25R)-spirost-5-en-3-ol | AKOS015961083 | DIOSGENIN | (25R)-5-Spirosten-3A-ol | K49P2K8WLX | MFCD00016887 | DIO...
- N-(3-Aminopropyl)cyclohexylamineCAS: 3312-60-5 Formula: C9H20N2 Molecular Weight: 156.27● In Stock — US warehouse, ships to EU* Item #: I137184View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N'-cyclohexylpropane-1,3-diamine
- SMILES
- C1CCC(CC1)NCCCN
- InChIKey
- ITZPOSYADVYECJ-UHFFFAOYSA-N
- InChI
- 1S/C9H20N2/c10-7-4-8-11-9-5-2-1-3-6-9/h9,11H,1-8,10H2
- Synonyms
- N-CYCLOHEXYLTRIMETHYLENEDIAMINE | N-CYCLOHEXYL-1,3-PROPANEDIAMINE | PDSP2_000330 | Bio1_001426 | NSC87572 | NSC-87572...
- Trastuzumab (anti-ERBB2)● In Stock — US warehouse, ships to EU* Item #: T305227View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB2
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- SMILES
- C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
- InChIKey
- FNXPTCITVCRFRK-UMMCILCDSA-N
- InChI
- 1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
- Synonyms
- 8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
- Perindopril, Inhibitor of Angiotensin-converting enzymeCAS: 82834-16-0 EC Number: 617-394-0 PubChem CID: 107807 Formula: C19H32N2O5 Molecular Weight: 368.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● In Stock — US warehouse, ships to EU* Item #: P334935View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
- SMILES
- CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O
- InChIKey
- IPVQLZZIHOAWMC-QXKUPLGCSA-N
- InChI
- 1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1
- Synonyms
- MFCD00055081 | Tox21_113087 | DB03260 | BSPBio_003206 | ethyl N-((2S)-1-((2S,3aS,7aS)-2-carboxyoctahydro-1H-indol-1-y...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
What should I consider when selecting a JAK/STAT Signaling product?
Define the transformation first, then narrow the JAK/STAT Signaling listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which JAK/STAT Signaling subcategory should I start with?
JAK/STAT Signaling is organised into EGFR, JAK, Pim and STAT. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering JAK/STAT Signaling?
Review the lot-specific Certificate of Analysis for the JAK/STAT Signaling product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search JAK/STAT Signaling by structure or CAS number?
Yes. Within JAK/STAT Signaling you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].