EGFR
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852 products
Popular Products
- Cetuximab (anti-EGFR), Antibody of epidermal growth factor receptorCAS: 205923-56-4 Formula: Molecular Weight: 145543.35Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: C411992View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Short Overview
- Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference...
- Patritumab (anti-ERBB3), INHIBITOR of Receptor tyrosine-protein kinase erbB-3 inhibitorCAS: 1262787-83-6Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170705View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB3
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Rat
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Anti-ERBB3 / HER3 Reference Antibody (patritumab) | Patritumab | Human Anti-ERBB3 Recombinant Antibody | c erbB 3 ant...
- Necitumumab (anti-EGFR), Antibody of epidermal growth factor receptorCAS: 906805-06-9Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab169264View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Recombinant Necitumumab Antibody | Anti-ERBB1 / EGFR / HER1 Reference Antibody (necitumumab) | Necitumumab (anti-EGFR...
- Margetuximab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2CAS: 1350624-75-7Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab170524View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB2
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
- WAY-339696CAS: 333419-97-9 Formula: C16H11BrN2O3 Molecular Weight: 359.17414● In Stock — US warehouse, ships to EU* Item #: W418133View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- OC1=C(C(=O)NC2=CC=CC(=C2)Br)C(=O)NC3=C1C=CC=C3
- Synonyms
- N-(3-bromophenyl)-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide
- BI-4142, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 2682003-36-5 Formula: C28H27N9O2 Molecular Weight: 521.57Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: B608049View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- O=C(N1CCN(CC1)C2=NC=C3N=CN=C(C3=N2)NC4=CC=C(C(C)=C4)OC5=CC(N=CN6C)=C6C=C5)C=C
- Synonyms
- BI4142;compound 8;example L-1
- PKI166, Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P612856View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-[4-[[(1R)-1-phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenol
- SMILES
- OC(C=C1)=CC=C1C2=CC3=C(N2)N=CN=C3N[C@H](C)C4=CC=CC=C4
- InChIKey
- XRYJULCDUUATMC-CYBMUJFWSA-N
- InChI
- 1S/C20H18N4O/c1-13(14-5-3-2-4-6-14)23-19-17-11-18(24-20(17)22-12-21-19)15-7-9-16(25)10-8-15/h2-13,25H,1H3,(H2,21,22,23,24)/t13-/m1/s1
- Synonyms
- UNII-9RIE5HW38P | CGP75166 | CGP-75166 | 4-(4-((1-phenylethyl)amino)-7H-pyrrolo(2,3-d)pyrimidin-6-yl)-phenol, R- | 4-...
- EpitinibCAS: 1203902-67-3 Formula: C24H26N6O2 Molecular Weight: 430.50Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: E610164View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- 4-ethyl-N-(4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)piperazine-1-carboxamide | D96105 | 4-ETHYL-N-{4-[(3-E...
- pyrotinib, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: P613029View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
- SMILES
- CCOc1cc2ncc(c(c2cc1NC(=O)/C=C/[C@H]1CCCN1C)Nc1ccc(c(c1)Cl)OCc1ccccn1)C#N
- InChIKey
- SADXACCFNXBCFY-IYNHSRRRSA-N
- InChI
- show more
- Synonyms
- SHR1258 | SHR-1258 | SCHEMBL9948753 | compound 12 [PMID: 28115222] | GTPL9662 | WZB08997 | (R,E)-N-(4-((3-chloro-4-(p...
- sacibertinibCAS: 1351941-69-9 PubChem CID: 89496273Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: S613392View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-[(3S)-oxolan-3-yl]oxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
- SMILES
- [C@@H]1(CCOC1)Oc1cc2ncc(C#N)c(Nc3ccc(OCc4ncccc4)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C
- InChIKey
- ZGYIXVSQHOKQRZ-COIATFDQSA-N
- InChI
- show more
- Synonyms
- (2E)-N-[(1(3)S)-5(3)-chloro-3(3)-cyano-2,6-dioxa-4-aza-3(7,4)-quinolina-8(2)-pyridina-1(3)-oxolana-5(1,4)-benzenaocta...
- selatinib, Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 2CAS: 1275595-86-2 PubChem CID: 51348455Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: S613520View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfinylethylamino)methyl]furan-2-yl]quinazolin-4-amine
- SMILES
- CS(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
- InChIKey
- OAMVGUFHZPRXOM-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- HY-116437 | Z2235824128 | GTPL9919 | UNII-6TLR8U8O3C | AT24534 | Selatinib | 4-Quinazolinamine, N-(3-chloro-4-((3-flu...
- simotinib, Epidermal growth factor receptor erbB1 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: S613586View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(3-chloro-4-fluorophenyl)-6-[2-(5,8-dioxa-10-azadispiro[2.0.44.33]undecan-10-yl)ethoxy]-7-methoxyquinazolin-4-amine
- SMILES
- COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCN4CC5(CC5)C6(C4)OCCO6
- InChIKey
- OXWUWXCJDBRCCG-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- SIM-6802 | 4-QUINAZOLINAMINE, N-(3-CHLORO-4-FLUOROPHENYL)-6-(2-(5,8-DIOXA-10-AZADISPIRO(2.0.4.3)UNDEC-10-YL)ETHOXY)-7...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.