EGFR
Browse by type, application, or key specifications such as purity, grade, packaging, and handling requirements.
852 products
Popular Products
- Theliatinib (HMPL-309), Inhibitor of epidermal growth factor receptor;Inhibitor of erb-b2 receptor tyrosine kinase 4;Inhibitor of LCK proto-oncogene; Src family tyrosine kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of tyrosine kinase non receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%● In Stock — US warehouse, ships to EU* Item #: T414072View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (3aR,6aR)-N-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]-1-methyl-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrole-5-carboxamide
- SMILES
- CN1CCC2C1CN(C2)C(=O)NC3=C(C=C4C(=C3)C(=NC=N4)NC5=CC=CC(=C5)C#C)OC
- InChIKey
- FSXCKIBROURMFT-VGSWGCGISA-N
- InChI
- show more
- Synonyms
- SCHEMBL247509 | AC-35865 | s8584 | AKOS032946520 | XILIERTINIB [WHO-DD] | 6ZZ3B7NZ0B | Pyrrolo(3,4-b)pyrrole-5(1H)-ca...
- Trastuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: T411999View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB2
- Short Overview
- Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- IUPAC Name
- 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- SMILES
- C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
- InChIKey
- FNXPTCITVCRFRK-UMMCILCDSA-N
- InChI
- 1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
- Synonyms
- 8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
- Tucatinib (Irbinitinib, ONT-380), Receptor protein-tyrosine kinase erbB-2 inhibitorCAS: 937263-43-9 EC Number: 876-089-2 PubChem CID: 51039094 Formula: C26H24N8O2 Molecular Weight: 480.52Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥96%● In Stock — US warehouse, ships to EU* Item #: T413986View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 6-N-(4,4-dimethyl-5H-1,3-oxazol-2-yl)-4-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazoline-4,6-diamine
- SMILES
- CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
- InChIKey
- SDEAXTCZPQIFQM-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- Irbinitinib | ONT-380 | Q25100690 | 6-N-(4,4-dimethyl-5H-1,3-oxazol-2-yl)-4-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyri...
- Tyrphostin AG 494CAS: 133550-35-3 EC Number: 810-936-9 PubChem CID: 5328771 Formula: C16H12N2O3 Molecular Weight: 280.2810mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T421272View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-phenylprop-2-enamide
- SMILES
- C1=CC=C(C=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
- InChIKey
- HKHOVJYOELRGMV-XYOKQWHBSA-N
- InChI
- 1S/C16H12N2O3/c17-10-12(8-11-6-7-14(19)15(20)9-11)16(21)18-13-4-2-1-3-5-13/h1-9,19-20H,(H,18,21)/b12-8+
- Synonyms
- MKXZASYAUGDDCJ-UHFFFAOYSA-N | DTXSID201018515 | HMS3414I07 | s6509 | AKOS024458583 | HMS2232N04 | NCGC00024687-02 | B...
- Tyrphostin AG 528CAS: 133550-49-9 EC Number: 834-693-3 PubChem CID: 1838043 Formula: C18H14N2O3 Molecular Weight: 306.32◐ .Made to order · 8–12 wks Item #: T394670View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-(2,3-dihydroindole-1-carbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
- SMILES
- C1CN(C2=CC=CC=C21)C(=O)C(=CC3=CC(=C(C=C3)O)O)C#N
- InChIKey
- MYKCTDWWIWGLHW-NTEUORMPSA-N
- InChI
- 1S/C18H14N2O3/c19-11-14(9-12-5-6-16(21)17(22)10-12)18(23)20-8-7-13-3-1-2-4-15(13)20/h1-6,9-10,21-22H,7-8H2/b14-9+
- Synonyms
- AC-35701 | BCP24141 | AG 528 | BDBM4314 | EX-A2364 | SMR001230652 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4...
- Tyrphostin AG 528CAS: 133550-49-9 EC Number: 834-693-3 PubChem CID: 1838043 Formula: C18H14N2O3 Molecular Weight: 306.32● In Stock — US warehouse, ships to EU* Item #: T337635View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-(2,3-dihydroindole-1-carbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
- SMILES
- C1CN(C2=CC=CC=C21)C(=O)C(=CC3=CC(=C(C=C3)O)O)C#N
- InChIKey
- MYKCTDWWIWGLHW-NTEUORMPSA-N
- InChI
- 1S/C18H14N2O3/c19-11-14(9-12-5-6-16(21)17(22)10-12)18(23)20-8-7-13-3-1-2-4-15(13)20/h1-6,9-10,21-22H,7-8H2/b14-9+
- Synonyms
- AC-35701 | BCP24141 | AG 528 | BDBM4314 | EX-A2364 | SMR001230652 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4...
- Tyrphostin AG 528CAS: 133550-49-9 EC Number: 834-693-3 PubChem CID: 1838043 Formula: C18H14N2O3 Molecular Weight: 306.3210mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T421273View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-2-(2,3-dihydroindole-1-carbonyl)-3-(3,4-dihydroxyphenyl)prop-2-enenitrile
- SMILES
- C1CN(C2=CC=CC=C21)C(=O)C(=CC3=CC(=C(C=C3)O)O)C#N
- InChIKey
- MYKCTDWWIWGLHW-NTEUORMPSA-N
- InChI
- 1S/C18H14N2O3/c19-11-14(9-12-5-6-16(21)17(22)10-12)18(23)20-8-7-13-3-1-2-4-15(13)20/h1-6,9-10,21-22H,7-8H2/b14-9+
- Synonyms
- AC-35701 | BCP24141 | AG 528 | BDBM4314 | EX-A2364 | SMR001230652 | (2E)-2-(2,3-dihydro-1H-indol-1-ylcarbonyl)-3-(3,4...
- Tyrphostin RG 1462010mM in DMSO● In Stock — US warehouse, ships to EU* Item #: T421398View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylprop-2-enenitrile
- SMILES
- C1=CC(=CN=C1)C(=CC2=CC(=CC(=C2)Cl)Cl)C#N
- InChIKey
- TYXIVBJQPBWBHO-QCDXTXTGSA-N
- InChI
- 1S/C14H8Cl2N2/c15-13-5-10(6-14(16)7-13)4-12(8-17)11-2-1-3-18-9-11/h1-7,9H/b12-4-
- Synonyms
- (E)-3-(3,5-dichlorophenyl)-2-(pyridin-3-yl)acrylonitrile | MFCD00236445 | (E)-3-(3,5-dichlorophenyl)-2-pyridin-3-ylpr...
- VEGFR Tyrosine Kinase Inhibitor II, Inhibitor of kinase insert domain receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: V338291View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-(4-chlorophenyl)-2-(pyridin-4-ylmethylamino)benzamide
- SMILES
- C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)Cl)NCC3=CC=NC=C3
- InChIKey
- GGPZCOONYBPZEW-UHFFFAOYSA-N
- InChI
- 1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)
- Synonyms
- GTPL6056 | AKOS030580576 | N-(4-Chlorophenyl)-2-[(pyridin-4-ylmethyl)amino]benzamide, VEGF Receptor Tyrosine Kinase I...
- WAY-311753-A● In Stock — US warehouse, ships to EU* Item #: W418505View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylamino)phenol
- SMILES
- C1CCC2=C(C1)C3=C(N=CN=C3S2)NC4=CC=C(C=C4)O
- InChIKey
- BTIBWAOCLJARHL-UHFFFAOYSA-N
- InChI
- 1S/C16H15N3OS/c20-11-7-5-10(6-8-11)19-15-14-12-3-1-2-4-13(12)21-16(14)18-9-17-15/h5-9,20H,1-4H2,(H,17,18,19)
- WAY-311753-A10mM in DMSO● In Stock — US warehouse, ships to EU* Item #: W423521View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 4-(5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-4-ylamino)phenol
- SMILES
- C1CCC2=C(C1)C3=C(N=CN=C3S2)NC4=CC=C(C=C4)O
- InChIKey
- BTIBWAOCLJARHL-UHFFFAOYSA-N
- InChI
- 1S/C16H15N3OS/c20-11-7-5-10(6-8-11)19-15-14-12-3-1-2-4-13(12)21-16(14)18-9-17-15/h5-9,20H,1-4H2,(H,17,18,19)
- WAY-339696CAS: 333419-97-9 Formula: C16H11BrN2O3 Molecular Weight: 359.1741410mM in DMSO◐ .Made to order · 8–12 wks Item #: W423431View ProductPricing & Pack Sizes
Technical Identifiers
- SMILES
- OC1=C(C(=O)NC2=CC=CC(=C2)Br)C(=O)NC3=C1C=CC=C3
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.