EGFR
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852 products
Popular Products
- ruserontinib, Tyrosine-protein kinase ABL inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: R613335View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 2-N-[4-(4-methylpiperazin-1-yl)phenyl]-9-propan-2-yl-8-N-pyridin-3-ylpurine-2,8-diamine
- SMILES
- CN1CCN(CC1)c1ccc(cc1)Nc1ncc2nc(n(c2n1)C(C)C)Nc1cnccc1
- InChIKey
- WSOHOUHPUOAXIN-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- 9-(1-Methylethyl)-N2-[4-(4-methyl-1-piperazinyl)phenyl]-N8-3-pyridinyl-9H-purine-2,8-diamine | 9H-Purine-2,8-diamine,...
- sunvozertinib, Inhibitor of Bruton tyrosine kinase;Inhibitor of epidermal growth factor receptorCAS: 2370013-12-8 PubChem CID: 139377809Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Made to order · 8–12 wks Item #: S613757View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- Clc1c(cc(c(Nc2nc(ncc2)Nc2c(cc(c(c2)NC(=O)C=C)N2C[C@@H](CC2)N(C)C)OC)c1)C(C)(C)O)F
- InChIKey
- BTMKEDDEMKKSEF-QGZVFWFLSA-N
- InChI
- show more
- Synonyms
- EX-A6612 | ASYM-122507 | HY-132842 | sunvozertinib | GLXC-25829 | DZ00000586 | GTPL11672 | Example 52 [WO2019149164A1...
- Amivantamab (anti-c-Met), Antibody of epidermal growth factor receptor;Antibody of MET proto-oncogene; receptor tyrosine kinaseCAS: 2171511-58-1Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab175451View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR MET
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Mouse
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- AUTS9 antibody | c met antibody | D249 antibody | Hepatocyte growth factor receptor antibody | HGF antibody | HGF rec...
- Trastuzumab emtansine (anti-ERBB2), INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitorCAS: 1018448-65-1 PubChem CID: 163341910Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥90%(SDS-PAGE&SEC-HPLC) See COA◐ .US Made to order · 2–4 wks Item #: Ab175686View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB2
- Short Overview
- Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (SMCC-DM1)
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- SMCC-DM1
- SMILES
- show more
- Synonyms
- Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
- BLU945, Inhibitor of epidermal growth factor receptorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: B608108View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- BLU 945 | BLU945 | BLU-945 | AKOS040759965 | UNII-PA4PTH5HL9 | 2660250-10-0 | 3-Isoquinolinamine, N-(2-((3S,4R)-3-flu...
- mavelertinib, Epidermal growth factor receptor erbB1 inhibitorCAS: 1776112-90-3 EC Number: 815-270-2 PubChem CID: 91668194 Formula: C18H22FN9O2 Molecular Weight: 415.42Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● In Stock — US warehouse, ships to EU* Item #: M611747View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-methylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide
- SMILES
- CN1C=C(C(=N1)OC)NC2=C3C(=NC(=N2)N4CC(C(C4)F)NC(=O)C=C)N(C=N3)C
- InChIKey
- JYIUNVOCEFIUIU-GHMZBOCLSA-N
- InChI
- show more
- Synonyms
- GTPL9765 | PF6747775 | AC-33593 | (2S,3S)-2,3-bis(4-methylbenzoyloxy)succinic acid | MAVELERTINIB [INN] | YXX2180047 ...
- tesevatinib, Receptor protein-tyrosine kinase erbB-2 inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: T614389View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- 7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6-methoxyquinazolin-4-amine
- SMILES
- CN1CC2CC(CC2C1)COC3=C(C=C4C(=C3)N=CN=C4NC5=C(C(=C(C=C5)Cl)Cl)F)OC
- InChIKey
- HVXKQKFEHMGHSL-GOOCMWNKSA-N
- InChI
- show more
- Synonyms
- 7-[[(3aS,6aR)-2-methyl-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]methoxy]-N-(3,4-dichloro-2-fluorophenyl)-6...
- Depatuxizumab mafodotin (anti-EGFR), BINDING AGENT of Epidermal growth factor receptor erbB1 binding agentCAS: 1585973-65-4Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab175508View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Short Overview
- Purity>95% ( SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (Mc-MMAF)
- Reactive species
- Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Mc-MMAF
- Synonyms
- Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody ...
- Nimotuzumab (anti-EGFR), INHIBITOR of Epidermal growth factor receptor erbB1 inhibitorCAS: 780758-10-3Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab175612View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- EGFR
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Cynomolgus monkey, Human
- Isotype
- Human IgG1
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody ...
- Seribantumab (anti-ERBB3), Antibody of erb-b2 receptor tyrosine kinase 3CAS: 1334296-12-6Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA● In Stock — US warehouse, ships to EU* Item #: Ab175653View ProductPricing & Pack Sizes
Technical Identifiers
- Associated targets
- ERBB3
- Short Overview
- Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
- Reactive species
- Human, Mouse
- Isotype
- Human IgG2
- Host species
- Human
- Conjugation
- Unconjugated
- Synonyms
- c erbB 3 antibody | c erbB3 antibody | Erb b2 receptor tyrosine kinase 3 antibody | ErbB 3 antibody | ERBB3 antibody ...
- (11R)-16-bromo-5,11,26-trimethyl-7-oxa-4,5,13,20,22,27-hexaazapentacyclo[22.3.1.0²,⁶.0¹³,²¹.0¹⁴,¹⁹]octacosa-1(28),2(6),3,14,16,18,21,24,26-nonaen-23-one◐ .Made to order · 8–12 wks Item #: B638046View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- show more
- SMILES
- CC1CCCOC2=C(C=NN2C)C3=NC(=CC(=C3)C(=O)NC4=NC5=C(N4C1)C=C(C=C5)Br)C
- InChIKey
- UPMBIKXABDDVHH-CQSZACIVSA-N
- InChI
- show more
- Synonyms
- EGFR-IN-15 | 2573869-16-4 | AKOS040757870 | HY-138746 | F89541
- TX1-85-1CAS: 1603845-32-4 Formula: C32H36N8O3 Molecular Weight: 580.68Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: T646130View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[5-[1-[4-(4-acetylpiperazin-1-yl)cyclohexyl]-4-aminopyrazolo[3,4-d]pyrimidin-3-yl]-2-phenoxyphenyl]prop-2-enamide
- SMILES
- CC(=O)N1CCN(CC1)C2CCC(CC2)N3C4=NC=NC(=C4C(=N3)C5=CC(=C(C=C5)OC6=CC=CC=C6)NC(=O)C=C)N
- InChIKey
- FYICDSWKKFSYOM-UHFFFAOYSA-N
- InChI
- show more
- Synonyms
- N-(5-(1-(4-(4-Acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-phenoxyphenyl)acrylamide
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.