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  1. Izalontamab (anti-EGFR&HER3)
    CAS: 2559704-24-2
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab182999
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    Technical Identifiers
    Short Overview
    Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1-REM; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
    Reactive species
    Human
    Isotype
    Human IgG1-REM
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    [Izalontamab]
    Synonyms
    Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody ...
  2. Jaceidin
    CAS: 10173-01-0 PubChem CID: 5464461 Formula: C18H16O8 Molecular Weight: 360.3
    ◐ .Made to order · 8–12 wks Item #: J709761
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    Technical Identifiers
    IUPAC Name
    5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-dimethoxychromen-4-one
    SMILES
    COC1=C(C=CC(=C1)C2=C(C(=O)C3=C(O2)C=C(C(=C3O)OC)O)OC)O
    InChIKey
    XUWTZJRCCPNNJR-UHFFFAOYSA-N
    InChI
    1S/C18H16O8/c1-23-11-6-8(4-5-9(11)19)16-18(25-3)15(22)13-12(26-16)7-10(20)17(24-2)14(13)21/h4-7,19-21H,1-3H3
  3. Disitamab (anti-ERBB2)
    CAS: 2185868-98-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab190126
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ERBB2
    Short Overview
    Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human, Mouse, Rat
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    [Disitamab]
    Synonyms
    Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
  4. Losatuxizumab (anti-EGFR)
    CAS: 1801544-27-3
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab190145
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    EGFR
    Short Overview
    Purity≥95% (SDS-PAGE&SEC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody ...
  5. Timigutuzumab (anti-ERBB2)
    CAS: 1665274-14-5
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab190134
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ERBB2
    Short Overview
    Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
  6. Coprelotamab (anti-ERBB2)
    CAS: 2348469-84-9
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    ● In Stock — US warehouse, ships to EU* Item #: Ab191934
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ERBB2
    Short Overview
    Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level≤1.0EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
    Reactive species
    Cynomolgus monkey, Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
  7. Lavendustin C
    CAS: 125697-93-0 EC Number: 635-029-3 PubChem CID: 3896 Formula: C14H13NO5 Molecular Weight: 275.26
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: L769919
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    Technical Identifiers
    IUPAC Name
    5-[(2,5-dihydroxyphenyl)methylamino]-2-hydroxybenzoic acid
    SMILES
    C1=CC(=C(C=C1NCC2=C(C=CC(=C2)O)O)C(=O)O)O
    InChIKey
    LULATDWLDJOKCX-UHFFFAOYSA-N
    InChI
    1S/C14H13NO5/c16-10-2-4-12(17)8(5-10)7-15-9-1-3-13(18)11(6-9)14(19)20/h1-6,15-18H,7H2,(H,19,20)
  8. Neratinib Maleate
    CAS: 915942-22-2 EC Number: 620-527-5 PubChem CID: 67307512 Formula: C34H33ClN6O7 Molecular Weight: 673.1
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: N768253
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    Technical Identifiers
    IUPAC Name
    (Z)-but-2-enedioic acid;(E)-N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
    SMILES
    CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C=CCN(C)C.C(=CC(=O)O)C(=O)O
    InChIKey
    VXZCUHNJXSIJIM-MEBGWEOYSA-N
    InChI
    1S/C30H29ClN6O3.C4H4O4/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22;5-3show more
  9. (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide hydrate
    CAS: 1042385-75-0 PubChem CID: 70693519 Formula: C24H27ClFN5O3 Molecular Weight: 488
    ◐ .Made to order · 8–12 wks Item #: N769834
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    Technical Identifiers
    IUPAC Name
    (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide;hydrate
    SMILES
    COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4.O
    InChIKey
    BSPLGGCPNTZPIH-IPZCTEOASA-N
    InChI
    1S/C24H25ClFN5O2.H2O/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31;/h5-8,12-15H,2-4,9-11H2,1Hshow more
  10. (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide hydrate
    CAS: 1042385-75-0 PubChem CID: 70693519 Formula: C24H27ClFN5O3 Molecular Weight: 488
    ◐ .Made to order · 8–12 wks Item #: N769839
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide;hydrate
    SMILES
    COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4.O
    InChIKey
    BSPLGGCPNTZPIH-IPZCTEOASA-N
    InChI
    1S/C24H25ClFN5O2.H2O/c1-33-22-14-20-17(24(28-15-27-20)29-16-7-8-19(26)18(25)12-16)13-21(22)30-23(32)6-5-11-31-9-3-2-4-10-31;/h5-8,12-15H,2-4,9-11H2,1Hshow more
  11. AZ7550 
    CAS: 1421373-99-0 PubChem CID: 71496459 Formula: C27H31N7O2 Molecular Weight: 485.58
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: A768931
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    Technical Identifiers
    IUPAC Name
    N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide
    SMILES
    CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC
    InChIKey
    ZROCWKZRGJYPTG-UHFFFAOYSA-N
    InChI
    1S/C27H31N7O2/c1-6-26(35)30-21-15-22(25(36-5)16-24(21)33(3)14-13-28-2)32-27-29-12-11-20(31-27)19-17-34(4)23-10-8-7-9-18(19)23/h6-12,15-17,28H,1,13-14Hshow more
    Synonyms
    N-(4-Methoxy-2-(methyl(2-(methylamino)ethyl)amino)-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino)phenyl)acrylamide
  12. Delphinidin chloride
    CAS: 528-53-0 EC Number: 208-437-0 Formula: C15H11ClO7 Molecular Weight: 338.70
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Made to order · 8–12 wks Item #: D769909
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    Technical Identifiers
    IUPAC Name
    2-(3,4,5-trihydroxyphenyl)chromenylium-3,5,7-triol;chloride
    SMILES
    C1=C(C=C(C(=C1O)O)O)C2=[O+]C3=CC(=CC(=C3C=C2O)O)O.[Cl-]
    InChIKey
    FFNDMZIBVDSQFI-UHFFFAOYSA-N
    InChI
    1S/C15H10O7.ClH/c16-7-3-9(17)8-5-12(20)15(22-13(8)4-7)6-1-10(18)14(21)11(19)2-6;/h1-5H,(H5-,16,17,18,19,20,21);1H
    Synonyms
    3,5,7-Trihydroxy-2-(3,4,5-trihydroxyphenyl)chromenylium chloride
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Frequently Asked Questions

How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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