EGFR
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- AST5902 mesylateCAS: 2412155-75-8 Formula: C28H33F3N8O5S Molecular Weight: 650.67◐ .Made to order · 8–12 wks Item #: A1435046View ProductPricing & Pack Sizes
Technical Identifiers
- AZ14133346Formula: C29H27N5O2 Molecular Weight: 477.56◐ .Made to order · 8–12 wks Item #: A1435048View ProductPricing & Pack Sizes
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- Afatinib-dFormula: C24H21D4ClFN5O3 Molecular Weight: 489.96◐ .Made to order · 8–12 wks Item #: A1421395View ProductPricing & Pack Sizes
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- Anticancer agent 158CAS: 2978685-72-0 Formula: C27H27N9OS2 Molecular Weight: 557.69◐ .Made to order · 8–12 wks Item #: A1435345View ProductPricing & Pack Sizes
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- Anticancer agent 133CAS: 2758905-51-8 Formula: C24H19Cl3N5ORh Molecular Weight: 602.71◐ .Made to order · 8–12 wks Item #: A1416989View ProductPricing & Pack Sizes
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- AsandeutertinibCAS: 1638281-46-5 Formula: C28H30D3N7O2 Molecular Weight: 502.63◐ .Made to order · 8–12 wks Item #: A1435003View ProductPricing & Pack Sizes
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- BI-4732CAS: 2769715-68-4 Formula: C32H36N10O2 Molecular Weight: 592.69◐ .Made to order · 8–12 wks Item #: B1435494View ProductPricing & Pack Sizes
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- BIHC◐ .Made to order · 8–12 wks Item #: B1433551View ProductPricing & Pack Sizes
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- IUPAC Name
- 3-[(2-butyl-4-chloro-1H-imidazol-5-yl)-(4-hydroxy-2-oxochromen-3-yl)methyl]-4-hydroxychromen-2-one
- SMILES
- CCCCC1=NC(=C(N1)C(C2=C(C3=CC=CC=C3OC2=O)O)C4=C(C5=CC=CC=C5OC4=O)O)Cl
- InChIKey
- YDLKVAMYKVCOFK-UHFFFAOYSA-N
- InChI
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- (R)-DZD1516CAS: 2387570-03-6 Formula: C28H27F2N7O3 Molecular Weight: 547.56◐ .Made to order · 8–12 wks Item #: R1434328View ProductPricing & Pack Sizes
Technical Identifiers
- (E/Z)-AG490CAS: 134036-52-5 Formula: C17H14N2O3 Molecular Weight: 294.30Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Made to order · 8–12 wks Item #: E1428924View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide
- SMILES
- C1=CC=C(C=C1)CNC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
- InChIKey
- TUCIOBMMDDOEMM-RIYZIHGNSA-N
- InChI
- 1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
- Synonyms
- N-Benzyl-2-cyano-3-(3,4-dihydroxyphenyl)acrylamide | (E/Z)-Tyrphostin AG490 | (E/Z)-Tyrphostin B42
- AFM24◐ .Made to order · 8–12 wks Item #: A1435522View ProductPricing & Pack Sizes
Technical Identifiers
- Anticancer agent 69Formula: C19H26N8S Molecular Weight: 398.53◐ .Made to order · 8–12 wks Item #: A1417448View ProductPricing & Pack Sizes
Technical Identifiers
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.