EGFR
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- Antiproliferative agent-54CAS: 1240322-54-6 Formula: C29H25F3N6O3 Molecular Weight: 562.54◐ .Made to order · 8–12 wks Item #: A1434332View ProductPricing & Pack Sizes
Technical Identifiers
- Antiproliferative agent-49Formula: C22H18N2O2S Molecular Weight: 374.46◐ .Made to order · 8–12 wks Item #: A1418629View ProductPricing & Pack Sizes
Technical Identifiers
- Antiproliferative agent-34CAS: 2910858-34-1 Formula: C27H27N7O5 Molecular Weight: 529.55◐ .Made to order · 8–12 wks Item #: A1434339View ProductPricing & Pack Sizes
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- Apoptosis inducer 35Formula: C23H21ClN8O2S2 Molecular Weight: 541.05◐ .Made to order · 8–12 wks Item #: A1417684View ProductPricing & Pack Sizes
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- BEBT-109CAS: 2050906-40-4 Formula: C27H32N8O3 Molecular Weight: 516.59◐ .Made to order · 8–12 wks Item #: B1434985View ProductPricing & Pack Sizes
Technical Identifiers
- BDTX-1535CAS: 2607829-38-7 Formula: C30H30ClFN6O2 Molecular Weight: 561.05Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Made to order · 8–12 wks Item #: B1435767View ProductPricing & Pack Sizes
Technical Identifiers
- Synonyms
- (E)-N-(4-((3-Chloro-2-fluorophenyl)amino)-7-(((1R,5S)-3-methyl-3-azabicyclo[3.1.0]hexan-1-yl)ethynyl)quinazolin-6-yl)...
- (R)-AfatinibCAS: 439081-17-1 PubChem CID: 10163178◐ .Made to order · 8–12 wks Item #: R1434984View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3R)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
- SMILES
- CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
- InChIKey
- ULXXDDBFHOBEHA-QDLOVBKTSA-N
- InChI
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- (Rac)-JBJ-04-125-02 acetateFormula: C29H26FN5O3S.1/3C2H4O2 Molecular Weight: 563.63◐ .Made to order · 8–12 wks Item #: R1435652View ProductPricing & Pack Sizes
Technical Identifiers
- 2-2(t) aptamer sodium◐ .Made to order · 8–12 wks Item #: T1434697View ProductPricing & Pack Sizes
Technical Identifiers
- AZ7550 hydrochlorideCAS: 2309762-40-9 PubChem CID: 132274051◐ .Made to order · 8–12 wks Item #: A1435468View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- N-[4-methoxy-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]-2-[methyl-[2-(methylamino)ethyl]amino]phenyl]prop-2-enamide;hydrochloride
- SMILES
- CNCCN(C)C1=CC(=C(C=C1NC(=O)C=C)NC2=NC=CC(=N2)C3=CN(C4=CC=CC=C43)C)OC.Cl
- InChIKey
- BHYPVGSNUFXTCM-UHFFFAOYSA-N
- InChI
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- AZ7550-dCAS: 2719690-99-8 Formula: C27H26D5N7O2 Molecular Weight: 490.61◐ .Made to order · 8–12 wks Item #: A1435185View ProductPricing & Pack Sizes
Technical Identifiers
- AZ5385CAS: 848439-89-4 Formula: C22H22ClFN4O4 Molecular Weight: 460.89◐ .Made to order · 8–12 wks Item #: A1421869View ProductPricing & Pack Sizes
Technical Identifiers
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.