EGFR
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- AZ-5104-dCAS: 2719691-01-5 Formula: C27H29D2N7O2 Molecular Weight: 487.59◐ .Made to order · 8–12 wks Item #: A1435022View ProductPricing & Pack Sizes
Technical Identifiers
- Afatinib oxalateCAS: 1398312-64-5 Formula: C26H27ClFN5O7 Molecular Weight: 575.97◐ .Made to order · 8–12 wks Item #: A1419748View ProductPricing & Pack Sizes
Technical Identifiers
- Afatinib impurity 11CAS: 1402086-20-7 Formula: C21H18ClFN4O3 Molecular Weight: 428.84◐ .Made to order · 8–12 wks Item #: A1423605View ProductPricing & Pack Sizes
Technical Identifiers
- Afatinib-d◐ .Made to order · 8–12 wks Item #: A1423581View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (E)-4-[bis(trideuteriomethyl)amino]-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]but-2-enamide
- SMILES
- CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4
- InChIKey
- ULXXDDBFHOBEHA-VCXSEIMGSA-N
- InChI
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- Afatinib-ddimaleateFormula: C32H27D6ClFN5O11 Molecular Weight: 724.12◐ .Made to order · 8–12 wks Item #: A1422584View ProductPricing & Pack Sizes
Technical Identifiers
- Anvatabart◐ .Made to order · 8–12 wks Item #: A1434253View ProductPricing & Pack Sizes
Technical Identifiers
- Avitinib maleate dihydrate◐ .Made to order · 8–12 wks Item #: A1417093View ProductPricing & Pack Sizes
Technical Identifiers
- IUPAC Name
- (Z)-but-2-enedioic acid;N-[3-[[2-[3-fluoro-4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide;dihydrate
- SMILES
- CN1CCN(CC1)C2=C(C=C(C=C2)NC3=NC4=C(C=CN4)C(=N3)OC5=CC=CC(=C5)NC(=O)C=C)F.C(=CC(=O)O)C(=O)O.O.O
- InChIKey
- QITOONQVTOGMOJ-IUJXYRIYSA-N
- InChI
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- Azerutamig◐ .Made to order · 8–12 wks Item #: A1435413View ProductPricing & Pack Sizes
Technical Identifiers
- BML-265CAS: 183321-62-2 Formula: C18H15N3O2 Molecular Weight: 305.33◐ .Made to order · 8–12 wks Item #: B1434203View ProductPricing & Pack Sizes
Technical Identifiers
- BL-B01D1◐ .Made to order · 8–12 wks Item #: B1423826View ProductPricing & Pack Sizes
Technical Identifiers
- BPI-15086CAS: 1644502-33-9 Formula: C29H33ClN8O4 Molecular Weight: 593.08◐ .Made to order · 8–12 wks Item #: B1434246View ProductPricing & Pack Sizes
Technical Identifiers
- Biotin HER-2 substrate peptideFormula: C93H140N22O25S3 Molecular Weight: 2062.43◐ .Made to order · 8–12 wks Item #: B1434744View ProductPricing & Pack Sizes
Technical Identifiers
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How is the EGFR listing put together?
It draws on reported EGFR annotations within JAK/STAT Signaling and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an EGFR modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the EGFR entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for EGFR compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For EGFR work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the EGFR compound I need is not listed?
Search by CAS number or SMILES first, since analogs of EGFR compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.