Activins and inhibins both belong to the TGF-β superfamily and are formed by different combinations of inhibin subunits, but they exert opposing effects on the regulation of pituitary follicle-stimulating hormone (FSH). Activins promote FSH synthesis and secretion, whereas inhibins restrict ...
fibrosis
Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.
Platelet-derived growth factor (PDGF) is a class of disulfide-linked dimeric growth factors. It was originally named because it is present in platelet α-granules and is released after platelet activation. PDGF can promote the proliferation, migration, and chemotaxis of smooth muscle cells, ...
Trichrome staining refers to a group of histochemical methods that use nuclear staining, cytoplasmic/muscle fiber staining, collagen or matrix counterstaining, and differentiation steps to display multiple structural components in the same tissue section. Its core value does not lie simply in ...
Connective tissue staining is mainly used to distinguish collagen fibers, reticular fibers, elastic fibers, matrix mucopolysaccharides, cartilage matrix, mineralized matrix, and related connective tissue cells.
The TGF-β signaling pathway is an important molecular network that regulates cell fate, tissue homeostasis, and pathological remodeling. This pathway is centered on ligand activation, receptor complex assembly, and Smad-dependent transcriptional regulation, while also intersecting with non-Smad ...
Transforming growth factor-β (TGF-β) is a core member of a multifunctional cytokine family and exerts systemic influence in embryonic development, immune homeostasis, tissue repair, extracellular matrix (ECM) remodeling, and regulation of the tumor microenvironment. TGF-β initiates signaling ...
Techniques often explored alongside immunological experiments.
