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224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items

PROTAC Linkers

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1,109 products
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  11. Fmoc-VAP-MMAE
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    Fmoc-VAP-MMAE
    CAS: 1912408-91-3 Formula: C70H98N8O13 Molecular Weight: 1259.57
    Solid ≥98%
    ◐ .Made to order · 8–12 wks Item #: F777708
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    [4-[[(2S)-2-[[(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-methylbutanoyl]amino]propanoyl]amino]phenyl]methyl N-[(2S)-1-[[(2S)-1-[[(3R,4S,5S)-1-[(2Sshow more
    SMILES
    CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)N(C)C(=O)OCC3=show more
    InChIKey
    DNBKSBZOHVIOEB-QKUOFYSQSA-N
    InChI
    1S/C70H98N8O13/c1-16-43(8)61(56(88-14)37-57(79)78-36-24-31-55(78)63(89-15)44(9)64(81)71-45(10)62(80)48-25-18-17-19-26-48)76(12)68(85)59(41(4)5)74-67(8show more
  12. Glucocorticoid receptor agonist-3 Ala-Ala-Mal
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    Glucocorticoid receptor agonist-3 Ala-Ala-Mal
    CAS: 3014393-35-9 Formula: C49H55FN4O12 Molecular Weight: 910.98
    ≥99%
    ◐ .Made to order · 8–12 wks Item #: G777713
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    Pricing & Pack Sizes
    Technical Identifiers
    IUPAC Name
    (2S)-2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]-N-[(2S)-1-[3-[[2-fluoro-3-[(1S,2S,4R,6S,8S,9S,11S,12S,13R)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyshow more
    SMILES
    CC1=C(C(=C(C=C1)OCC2=CC(=CC=C2)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCN3C(=O)C=CC3=O)F)[C@H]4O[C@@H]5C[C@H]6[C@@H]7CCC8=CC(=O)C=C[C@@]8([C@H]7[C@H](C[C@@show more
    InChIKey
    BISHTACTVXELTJ-VFAPTOKSSA-N
    InChI
    1S/C49H55FN4O12/c1-25-9-12-35(64-24-28-7-6-8-30(19-28)53-45(63)27(3)52-44(62)26(2)51-38(59)16-18-54-39(60)13-14-40(54)61)43(50)41(25)46-65-37-21-33-32show more
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Frequently Asked Questions

What should I consider when selecting PROTAC Linkers?
When selecting PROTAC Linkers, consider the coupling chemistry available on both partners, whether the linker needs to be cleavable, and how length and hydrophilicity will affect solubility of the final conjugate. Test a short series rather than committing to one geometry.
What does PROTAC Linkers cover?
PROTAC Linkers is a top-level listing in our catalogue. Use the filters and search on the listing page to narrow by the attributes that matter for your work, or browse the neighbouring categories from the main navigation.
Which quality data should I check for PROTAC Linkers?
Review HPLC purity and MS identity for the PROTAC Linkers lot and, where relevant, the polydispersity index, plus residual solvent and water content. For reactive esters and similar handles, the retest date matters as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I find PROTAC Linkers by reactive group or linker length?
Yes — filter PROTAC Linkers by reactive handle, linker length or PEG units, and cleavability, and search by CAS number or SMILES for exact structures. Custom linkers and bulk quantities: [email protected].
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