Plasmin from Human Plasma, CAS No.9001-90-5

CAS: 9001-90-5 Cat. No.: np001029 Molecular Weight: 81000

GRADE & PURITY Native, EnzymoPure™, ≥90%(SDS-PAGE), ≥15 U/mg protein; Protein concentration: See COA

Accession #

P00747

Bioactivity

≥15 U/mg protein

Overview

Plasmin functions in fibrinolysis, fibrinogenolysis, as well as in the complement cascade. This protease has been prepared by using streptokinase to activate human plasma plasminogen.

Extinction Coefficient: 1.71  
Prepared from plasma shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.

Specifications

Product Name

Plasmin from Human Plasma, CAS No.9001-90-5

Synonyms

Fibrinolysin | fibrinase | PLG | HAE4

Grade

Native, EnzymoPure™

Specifications & Purity

Native, EnzymoPure™, ≥90%(SDS-PAGE), ≥15 U/mg protein; Protein concentration: See COA

Biochemical and Physiological Mechanisms

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It

Bioactivity

≥15 U/mg protein

Accession #

P00747

Predicted molecular weight

81 kDa

CAS

9001-90-5

Enzyme Commission Number

EC 3.4.21.7

Molecule Type

Enzyme

Storage and Shipping

Shape

Frozen in 100 mM Na phosphate, pH 7.3, with 1 mM 6-aminohexanoic acid and 25% glycerol

Concentration

≥15 U/mg protein; Protein concentration: See COA

Storage

Store at -80°C,Avoid repeated freezing and thawing

Shipped In

Dry ice packs + Cold packs

Stability And Storage

Store at -80℃ long term (>1 year).   Upon reconstitution, it is recommended to aliquot. Avoid freeze/thaw cycle.

Unit definition

One unit is defined as the amount of enzyme that hydrolyzes one umole of tosyl-Gly-Pro-Lys-pNA per minute at 25°C, pH 7.8.  Note: One unit=1.25 CU.