KF26777 - Moligand™ , Antagonist of A 1 receptor;Antagonist of A 2A receptor;Antagonist of A 2B receptor;Antagonist of A 3 receptor, CAS No.206129-88-6, Antagonist of A 1 receptor;Antagonist of A 2A receptor;Antagonist of A 2B receptor;Antagonist of A 3 receptor

CAS: 206129-88-6 Cat. No.: K611332 PubChem CID: 135409562

GRADE & PURITY Moligand™

Synonyms

KF 26777 | 5H-Imidazo(2,1-i)purin-5-one, 2-(4-bromophenyl)-1,4,7,8-tetrahydro-4-propyl- | N33070GI64 | 2-(4-bromophenyl)-4-propyl-7,8-dihydro-1H-imidazo[2,1-f]purin-5-one | L017723 | Q27894221 | DTXSID101028432 | 5H-Imidazo(2,1-i)purin-5-one, 2-(4-bromoph

Storage

Room temperature

Specifications

Synonymes

KF 26777 | 5H-Imidazo(2,1-i)purin-5-one, 2-(4-bromophenyl)-1,4,7,8-tetrahydro-4-propyl- | N33070GI64 | 2-(4-bromophenyl)-4-propyl-7,8-dihydro-1H-imidazo[2,1-f]purin-5-one | L017723 | Q27894221 | DTXSID101028432 | 5H-Imidazo(2,1-i)purin-5-one, 2-(4-bromoph

Spécifications et pureté

Moligand™

Conditions de stockage de stockage

Room temperature

Grade

Moligand™

Type d'action

ANTAGONIST

Mécanisme d'action

Antagonist of A 1 receptor;Antagonist of A 2A receptor;Antagonist of A 2B receptor;Antagonist of A 3 receptor

Noms et identifiants

• Sourires canoniques: CCCN1C2=NC(=NC2=C3NCCN3C1=O)C4=CC=C(C=C4)Br
• IUPAC Name: 2-(4-bromophenyl)-4-propyl-8,9-dihydro-7H-imidazo[2,1-f]purin-5-one
• InChIKey: OPUXIXJLNLMIKY-UHFFFAOYSA-N
• INCHI: 1S/C16H16BrN5O/c1-2-8-21-15-12(14-18-7-9-22(14)16(21)23)19-13(20-15)10-3-5-11(17)6-4-10/h3-6,18H,2,7-9H2,1H3
• Isomères SMILES: CCCN1C2=NC(=NC2=C3NCCN3C1=O)C4=CC=C(C=C4)Br
• CAS alternatif: 206129-88-6
• PubChem CID: 135409562
• Termes d'entrée MeSH: 2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo(2,1-i)purin-5(4H)-one dihydrochloride;KF 26777;KF26777

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Azoles
      • Subclass Imidazoles
        • Level5 Substituted imidazoles
          • Level6 Phenylimidazoles

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Azoles
• Subclass: Imidazoles
• Intermediate Tree Nodes: Substituted imidazoles
• Direct Parent: Phenylimidazoles
• Alternative Parents: 6-alkylaminopurines Purinones Secondary alkylarylamines Pyrimidones Bromobenzenes Aryl bromides Heteroaromatic compounds Ureas Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organobromides Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-alkylaminopurine - 2-phenylimidazole - Purinone - Purine - Imidazopyrimidine - Secondary aliphatic/aromatic amine - Pyrimidone - Halobenzene - Bromobenzene - Benzenoid - Pyrimidine - Monocyclic benzene moiety - Aryl halide - Aryl bromide - Heteroaromatic compound - Urea - Azacycle - Secondary amine - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organobromide - Organohalogen compound - Amine - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as phenylimidazoles. These are polycyclic aromatic compounds containing a benzene ring linked to an imidazole ring through a CC or CN bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

ADORA2A Tclin Adenosine receptor A2a (1 Activities)

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ADORA2B Tclin Adenosine receptor A2b (1 Activities)

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ADORA1 Tclin Adenosine receptor A1 (1 Activities)

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ADORA3 Tchem Adenosine receptor A3 (2 Activities)

Discover Target: ADORA3

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ADORA1 Tclin Adenosine A1 receptor (17603 Activities)

Discover Target: ADORA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA2A Tclin Adenosine A2a receptor (16305 Activities)

Discover Target: ADORA2A

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

Discover Target: ADORA3

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Mécanismes d'action