L-Lysine - Moligand™, 10mM in Water , Agonist of GPRC6 receptor, CAS No.56-87-1, Agonist of GPRC6 receptor

CAS: 56-87-1 Cat. No.: L424803 Formule: C₆H₁₄N₂O₂ Poids moléculaire: 146.19 Beilstein Registry Number: 1722531 Numéro CE: 200-294-2

QUALITÉ & PURETÉ Moligand™, 10mM in Water

Synonyms

H-Lys-OH | (-)-lysine | BDBM217367 | s5630 | (S)-a,e-Diaminocaproate | 3H-Lysine | alpha-Lysine | B05XB03 | L-?Lysine | lysine | (S)-2,6-Diaminocaproic acid | Aminutrin | L-2,6-Diainohexanoic acid | 2,6-Diaminohexanoic acid, (S)- | EINECS 200-294-2 | GTPL

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

A moderate serotonin antagonist and essential amino acid.

Spécifications

Synonymes

H-Lys-OH | (-)-lysine | BDBM217367 | s5630 | (S)-a,e-Diaminocaproate | 3H-Lysine | alpha-Lysine | B05XB03 | L-?Lysine | lysine | (S)-2,6-Diaminocaproic acid | Aminutrin | L-2,6-Diainohexanoic acid | 2,6-Diaminohexanoic acid, (S)- | EINECS 200-294-2 | GTPL

Spécifications et pureté

Moligand™, 10mM in Water

Mécanismes biochimiques et physiologiques

L-Lysine is an essential α-amino acid, which is encoded by the codons AAA and AAG. Studies suggest that L-Lysine is a key building block in protein synthesis in which it acts as a base. The poly L-Lysine form can be used to suppress prion propagation in m

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Type d'action

AGONIST

Mécanisme d'action

Agonist of GPRC6 receptor

Noms et identifiants

Pubchem Sid

528765244

Sourires canoniques

C(CCN)CC(C(=O)O)N

IUPAC Name

(2S)-2,6-diaminohexanoic acid

InChIKey

KDXKERNSBIXSRK-YFKPBYRVSA-N

INCHI

1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)/t5-/m0/s1

Isomères SMILES

C(CCN)C[C@@H](C(=O)O)N

WGK Allemagne

1

RTECS

OL5540000

Poids moléculaire

146.19

Beilstein

1722531

Reaxy-Rn

1616991

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1616991&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Medium-chain fatty acids Amino fatty acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Medium-chain fatty acid - Amino fatty acid - Fatty acid - Fatty acyl - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Organic nitrogen compound - Amine - Hydrocarbon derivative - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Common amino acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Cibles associées (humaines)

GPRC6A Tchem G-protein coupled receptor family C group 6 member A (1 Activities)

Discover Target: GPRC6A

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

GSR Tclin Glutathione reductase (335 Activities)

Discover Target: GSR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC7A5 Tchem L-type amino acid transporter 1 (388 Activities)

Discover Target: SLC7A5

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Skin (286 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC16A10 SLC16A10 protein (28 Activities)

Discover Target: SLC16A10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Cibles associées (non humaines)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

dapA Dihydrodipicolinate synthase (65 Activities)

Discover Target: dapA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Escherichia coli (133304 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Bacillus subtilis (32866 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Internal ribosome entry site (IRES) (199 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc22a4 Solute carrier family 22 member 4 (11 Activities)

Discover Target: Slc22a4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Slc16a10 Monocarboxylate transporter 10 (73 Activities)

Discover Target: Slc16a10

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Vicia faba (57 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GAP1 General amino-acid permease GAP1 (481 Activities)

Discover Target: GAP1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SARS-CoV-2 (38078 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mécanismes d'action

Propriétés chimiques et physiques

• Sensibilité: Hygroscopic
• Rotation spécifique [α]: 26 ° (C=2, 5mol/L HCl)
• Point de fusion (°C): 215 °C (dec.) (lit.)
• Poids moléculaire: 146.190 g/mol
• XLogP3: -3.000
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 146.106 Da
• Monoisotopic Mass: 146.106 Da
• Topological Polar Surface Area: 89.300 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 106.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1