LG 100754 - Moligand™, ≥98% , Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ, CAS No.180713-37-5, Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ
LG 100754 - Moligand™, ≥98% , Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ, CAS No.180713-37-5, Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ
QUALITÉ & PURETÉMoligand™?Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.≥98%
Moligand™, ≥98% Moligand™ pour les flux de travail chromatographiques et analytiques sensibles nécessitant une interférence de ligne de base minimale.
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Stockage & expédition
Store at -20°C Expédition Ice chest + Ice pads. Consultez le COA spécifique au lot pour les spécifications exactes.
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Documents qualité
SDS, COA, fiche technique et fiche de spécifications disponibles au téléchargement. COA spécifique au lot accessible via la recherche par numéro de lot.
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Preuve documentaire
Cité dans 0 publications à comité de lecture couvrant la chromatographie, la synthèse organique et les réactions de couplage croisé.
Vue d’ensemble
Application:
LG100754 (UVI 2112) is a modulator of RXR dimers. LG100754 acts as an antagonist of the homodimeric RXR:RXR, but as an agonist of the heterodimeric RXR:PPARα and RXR:PPARγ. LG100754 is an insulin sensitizer acting through RXR.
LG100754 is a unique RXR ligand that acts as an antagonist against RXR homodimers, but is a strong agonist for RXR:PPARα and RXR:PPARγ heterodimers. The compound does not have agonist activities for other RXR heterodimers containing LXR or GAR/FXR recepto
Conditions de stockage de stockage
Store at -20°C
Expédié en
Ice chest + Ice pads
Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.
Grade
Moligand™
Type d'action
AGONIST, ANTAGONIST
Mécanisme d'action
Agonist of Peroxisome proliferator-activated receptor-γ;Antagonist of Retinoid X receptor-α;Antagonist of Retinoid X receptor-β;Antagonist of Retinoid X receptor-γ
This compound belongs to the class of organic compounds known as retinoids. These are oxygenated derivatives of 3,7-dimethyl-1-(2,6,6-trimethylcyclohex-1-enyl)nona-1,3,5,7-tetraene and derivatives thereof.
External Descriptors
Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Certificats (CoA, COO, BSE/TSE et tableau d'analyse)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriétés chimiques et physiques
Solubilité
Solvent:DMSO, Max Conc. mg/mL: 39.66, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 19.83, Max Conc. mM: 50
Poids moléculaire
396.600 g/mol
XLogP3
8.400
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Rotatable Bond Count
7
Exact Mass
396.266 Da
Monoisotopic Mass
396.266 Da
Topological Polar Surface Area
46.500 Ų
Heavy Atom Count
29
Formal Charge
0
Complexity
665.000
Isotope Atom Count
0
Defined Atom Stereocenter Count
0
Undefined Atom Stereocenter Count
0
Defined Bond Stereocenter Count
3
Undefined Bond Stereocenter Count
0
The total count of all stereochemical bonds
3
Covalently-Bonded Unit Count
1
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Avis
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Foire aux questions
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 180713-37-5, the molecular formula is C26H36O3, and the molecular weight is 396.56 g/mol. InChIKey HNODNXQAYXJFMQ-LQUSFLDPSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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Notre guide de sélection des qualités couvre la pureté, le statut du stabilisant et l'adéquation à l'application pour toutes les variantes de notre catalogue.
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