kinase RIP
146 produits
Produits
- GSK872CAS: 1346546-69-7 Formule: C19H17N3O2S2 Poids moléculaire: 383.48Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G276439Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-(6-propan-2-ylsulfonylquinolin-4-yl)-1,3-benzothiazol-5-amine
- SMILES
- CC(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=CC4=C(C=C3)SC=N4
- InChIKey
- ZCDBTQNFAPKACC-UHFFFAOYSA-N
- InChI
- 1S/C19H17N3O2S2/c1-12(2)26(23,24)14-4-5-16-15(10-14)17(7-8-20-16)22-13-3-6-19-18(9-13)21-11-25-19/h3-12H,1-2H3,(H,20,22)
- Synonymes
- GSK′872 | N-(6-(Isopropylsulfonyl)quinolin-4-yl)benzo[d]thiazol-5-amine
- GSK 583, Inhibitor of receptor interacting serine/threonine kinase 2CAS: 1346547-00-9 Formule: C20H19FN4O2S Poids moléculaire: 398.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G286537Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-tert-butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine
- SMILES
- CC(C)(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=NNC4=C3C=C(C=C4)F
- InChIKey
- XLOGLWKOHPIJLV-UHFFFAOYSA-N
- InChI
- 1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)
- Synonymes
- GSK 583 | GSK-2616583A
- Necrostatin-1, Inhibitor of indoleamine 2;3-dioxygenase 1;Inhibitor of receptor interacting serine/threonine kinase 1CAS: 4311-88-0 Formule: C13H13N3OS Poids moléculaire: 259.33Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: N125522Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylideneimidazolidin-4-one
- SMILES
- CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
- InChIKey
- TXUWMXQFNYDOEZ-UHFFFAOYSA-N
- InChI
- 1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)
- Synonymes
- 5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanyl-3,5-dihydro-4H-imidazol-4-one | 5-(1H-indol-3-ylmethyl)-3-methyl-2-thioxo...
- Necrostatin-5CAS: 337349-54-9 Formule: C19H17N3O2S2 Poids moléculaire: 383.49● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: N274792Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 2-[[3-(4-methoxyphenyl)-4-oxo-5,6,7,8-tetrahydro-[1]benzothiolo[2,3-d]pyrimidin-2-yl]sulfanyl]acetonitrile
- SMILES
- COC1=CC=C(C=C1)N2C(=O)C3=C(N=C2SCC#N)SC4=C3CCCC4
- InChIKey
- VGONMECBFMCKBS-UHFFFAOYSA-N
- InChI
- 1S/C19H17N3O2S2/c1-24-13-8-6-12(7-9-13)22-18(23)16-14-4-2-3-5-15(14)26-17(16)21-19(22)25-11-10-20/h6-9H,2-5,11H2,1H3
- Synonymes
- STL304760 | SCHEMBL12682848 | Necrostatin-5, >=98% (HPLC), solid | AKOS000510375 | Oprea1_213608 | Oprea1_435788 | HM...
- Primidone, Sodium channel alpha subunit blockerMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P129217Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-ethyl-5-phenyl-1,3-diazinane-4,6-dione
- SMILES
- CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
- InChIKey
- DQMZLTXERSFNPB-UHFFFAOYSA-N
- InChI
- 1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)
- Synonymes
- 5-Phenyl-5-ethyl-hexahydropyrimidine-4,6-dione | Primidone (Mysoline) | PRIMIDONE (USP-RS) | Pyrimidone ''Medi-pets''...
- 7-Cl-O-Nec1, Inhibitor of receptor interacting serine/threonine kinase 1CAS: 852391-15-2 Formule: C13H12ClN3O2 Poids moléculaire: 277.7Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: C275378Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione
- SMILES
- CN1C(=O)C(NC1=O)CC2=CNC3=C2C=CC=C3Cl
- InChIKey
- WIKGAEMMNQTUGL-UHFFFAOYSA-N
- InChI
- 1S/C13H12ClN3O2/c1-17-12(18)10(16-13(17)19)5-7-6-15-11-8(7)3-2-4-9(11)14/h2-4,6,10,15H,5H2,1H3,(H,16,19)
- Synonymes
- 5-((7-Chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione | Necrostatin 2 racemate (Nec-1s) | Necrostatin-1 ...
- OD36, Inhibitor of receptor interacting serine/threonine kinase 2CAS: 1638644-62-8 Formule: C16H15ClN4O2 Poids moléculaire: 330.77Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%◐ .Sur commande · 8–12 semaines Article #: O287326Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-chloro-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene
- SMILES
- C1COCCOC2=CC(=CC(=C2)C3=C4N=C(N1)C=CN4N=C3)Cl
- InChIKey
- KTSDBMVHAKWDRK-UHFFFAOYSA-N
- InChI
- 1S/C16H15ClN4O2/c17-12-7-11-8-13(9-12)23-6-5-22-4-2-18-15-1-3-21-16(20-15)14(11)10-19-21/h1,3,7-10H,2,4-6H2,(H,18,20)
- Synonymes
- 6-Chloro-10,11,14,17-tetrahydro-13H-1,16-etheno-4,8-metheno-1H-pyrazolo[3,4-g][1,14,4,6]dioxadiazacyclohexadecine hyd...
- Primidone-d5CAS: 73738-06-4 Formule: C12H9D5N2O2 Poids moléculaire: 223.28● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P334356Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-(1,1,2,2,2-pentadeuterioethyl)-5-phenyl-1,3-diazinane-4,6-dione
- SMILES
- CCC1(C(=O)NCNC1=O)C2=CC=CC=C2
- InChIKey
- DQMZLTXERSFNPB-ZBJDZAJPSA-N
- InChI
- 1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)/i1D3,2D2
- Synonymes
- 5-(Ethyl-d5)dihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione | AKOS030242911 | HY-B0339S | 5-(1,1,2,2,2-pentadeuterioethyl...
- GSK 583, Inhibitor of receptor interacting serine/threonine kinase 2CAS: 1346547-00-9 Formule: C20H19FN4O2S Poids moléculaire: 398.45Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G421308Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-tert-butylsulfonyl-N-(5-fluoro-1H-indazol-3-yl)quinolin-4-amine
- SMILES
- CC(C)(C)S(=O)(=O)C1=CC2=C(C=CN=C2C=C1)NC3=NNC4=C3C=C(C=C4)F
- InChIKey
- XLOGLWKOHPIJLV-UHFFFAOYSA-N
- InChI
- 1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)
- Synonymes
- 6-[(1,1-Dimethylethyl)sulfonyl]-N-(5-fluoro-1H-indazol-3-yl)-4-quinolinamine
- GSK'547, Inhibitor of receptor interacting serine/threonine kinase 1CAS: 2226735-55-1 Formule: C20H18F2N6O Poids moléculaire: 396.39Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G422673Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile
- SMILES
- C1CN(CCC1C(=O)N2C(CC=N2)C3=CC(=CC(=C3)F)F)C4=NC=NC(=C4)C#N
- InChIKey
- SJVGFKBLUYAEOK-SFHVURJKSA-N
- InChI
- 1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5-27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0/s1
- Synonymes
- 4-Pyrimidinecarbonitrile,6-[4-[[(5S)-5-(3,5-difluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]carbonyl]-�...
- GSK547, Inhibitor of receptor interacting serine/threonine kinase 1CAS: 2226735-55-1 Formule: C20H18F2N6O Poids moléculaire: 396.39Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G414181Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile
- SMILES
- C1CN(CCC1C(=O)N2C(CC=N2)C3=CC(=CC(=C3)F)F)C4=NC=NC(=C4)C#N
- InChIKey
- SJVGFKBLUYAEOK-SFHVURJKSA-N
- InChI
- 1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5-27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0/s1
- Synonymes
- 4-Pyrimidinecarbonitrile,6-[4-[[(5S)-5-(3,5-difluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl]carbonyl]-�...
- GSK'963, Inhibitor of receptor interacting serine/threonine kinase 1CAS: 2049868-46-2 Formule: C14H18N2O Poids moléculaire: 230.31Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G422489Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 2,2-dimethyl-1-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one
- SMILES
- CC(C)(C)C(=O)N1C(CC=N1)C2=CC=CC=C2
- InChIKey
- NJQVSLWJBLPTMD-LBPRGKRZSA-N
- InChI
- 1S/C14H18N2O/c1-14(2,3)13(17)16-12(9-10-15-16)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3/t12-/m0/s1
- Synonymes
- 1-Propanone,1-[(5S)-4,5-dihydro-5-phenyl-1H-pyrazol-1-yl]-2,2-dimethyl-
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Foire aux questions
Which compounds are listed for RIP kinase?
Compounds associated with RIP kinase are grouped here under the Apoptosis classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does RIP kinase sit within Apoptosis?
RIP kinase is one target listing within the Apoptosis classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from RIP kinase?
For compounds listed under RIP kinase, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for RIP kinase?
Browse the parent Apoptosis listing to reach targets neighbouring RIP kinase, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.