MARCKS

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  1. TPPB
    CAS: 497259-23-1 PubChem CID: 9935767 Formule: C27H30F3N3O3 Poids moléculaire: 501.54
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: T303812
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    Nom IUPAC
    (2E,4E)-N-[(2S,5S)-5-(hydroxymethyl)-1-methyl-3-oxo-2-propan-2-yl-2,4,5,6-tetrahydro-1,4-benzodiazocin-8-yl]-5-[4-(trifluoromethyl)phenyl]penta-2,4-dishow more
    SMILES
    CC(C)C1C(=O)NC(CC2=C(N1C)C=CC(=C2)NC(=O)C=CC=CC3=CC=C(C=C3)C(F)(F)F)CO
    InChIKey
    WOLVEMPZUIFSII-IHHOKICGSA-N
    InChI
    1S/C27H30F3N3O3/c1-17(2)25-26(36)32-22(16-34)15-19-14-21(12-13-23(19)33(25)3)31-24(35)7-5-4-6-18-8-10-20(11-9-18)27(28,29)30/h4-14,17,22,25,34H,15-16Hshow more
    Synonymes
    AS-82981 | WOLVEMPZUIFSII-IHHOKICGSA-N | PKC Activator V | 5-(4-Trifluoromethyl-phenyl)-penta-2,4-dienoic acid (5-hyd...
  2. Sotrastaurin, Protein kinase C (PKC) inhibitor
    CAS: 425637-18-9 PubChem CID: 10296883 Formule: C25H22N6O2 Poids moléculaire: 438.49
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S125985
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    Nom IUPAC
    3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione
    SMILES
    CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=C(C(=O)NC4=O)C5=CNC6=CC=CC=C65
    InChIKey
    OAVGBZOFDPFGPJ-UHFFFAOYSA-N
    InChI
    1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,show more
    Synonymes
    AKOS027422723 | 3-(1H-Indol-3-yl)-4-(2-(4-methylpiperazin-1-yl)quinazolin-4-yl)-1H-pyrrole-2,5-dione | EX-A2802 | 105...
  3. balanol, Inhibitor of beta adrenergic receptor kinase 1;Inhibitor of beta adrenergic receptor kinase 2;Inhibitor of G protein-coupled receptor kinase 1;Inhibitor of G protein-coupled receptor kinase 4;Inhibitor of G protein-coupled receptor kinase 6;Inhibitor of G
    CAS: 63590-19-2 PubChem CID: 5287736 Formule: C28H26N2O10 Poids moléculaire: 550.51
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    ◐ .Sur commande · 8–12 semaines Article #: B607920
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    Nom IUPAC
    2-[2,6-dihydroxy-4-[(3R,4R)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]oxycarbonylbenzoyl]-3-hydroxybenzoic acid
    SMILES
    C1CC(C(CNC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O
    InChIKey
    XYUFCXJZFZPEJD-XMSQKQJNSA-N
    InChI
    1S/C28H26N2O10/c31-16-8-6-14(7-9-16)26(36)30-18-13-29-10-2-5-22(18)40-28(39)15-11-20(33)24(21(34)12-15)25(35)23-17(27(37)38)3-1-4-19(23)32/h1,3-4,6-9,show more
    Synonymes
    Azepinostatin | Balanol, 1 | Q4850048 | BDBM3149 | BENZOIC ACID, 4-(2-CARBOXY-6-HYDROXYBENZOYL)-3,5-DIHYDROXY-, 1-(HE...
  4. VU0364572 TFA
    CAS: 1240514-89-9 PubChem CID: 91885398
    ◐ .Sur commande · 8–12 semaines Article #: V1428420
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    Nom IUPAC
    ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate;2,2,2-trifluoroacetic acid
    SMILES
    CCOC(=O)N1CCC(CC1)N2CCCC(C2)NC(=O)C3=CC=CC=C3C.C(=O)(C(F)(F)F)O
    InChIKey
    QEFQJTFXOBPBLZ-UNTBIKODSA-N
    InChI
    1S/C21H31N3O3.C2HF3O2/c1-3-27-21(26)23-13-10-18(11-14-23)24-12-6-8-17(15-24)22-20(25)19-9-5-4-7-16(19)2;3-2(4,5)1(6)7/h4-5,7,9,17-18H,3,6,8,10-15H2,1-show more
  5. BIO-11006 acetate
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in Water
    ◐ .Sur commande · 8–12 semaines Article #: B1493853
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Foire aux questions

How is the MARCKS listing put together?
It draws on reported MARCKS annotations within Cytoskeleton and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MARCKS modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MARCKS entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MARCKS compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MARCKS work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MARCKS compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MARCKS compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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