Découvrez des composés axés sur les voies métaboliques destinés à la recherche en épigénétique, notamment des outils liés à la régulation de la chromatine et au contrôle transcriptionnel. Utilisez cette page pour comparer les molécules employées dans les processus de validation des cibles, d'étude des mécanismes et de modulation de l'état cellulaire.
Épigénétique
Produits
- 5-Aza-2′-deoxycytidine, DNA (cytosine-5)-methyltransferase 1 inhibitorSolid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: A119533Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one
- SMILES
- C1C(C(OC1N2C=NC(=NC2=O)N)CO)O
- InChIKey
- XAUDJQYHKZQPEU-KVQBGUIXSA-N
- InChI
- 1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15)/t4-,5+,6+/m0/s1
- Synonymes
- 2-deoxyazacytidine | 5-Aza-2'-deoxycytidine, >=97% | 4-Amino-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-s-triazin-2(1H...
- S-Ruxolitinib (INCB018424), Inhibitor of Janus kinase 1;Inhibitor of Janus kinase 2;Inhibitor of Janus kinase 3;Inhibitor of tyrosine kinase 2Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S129613Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (3S)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile
- SMILES
- C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
- InChIKey
- HFNKQEVNSGCOJV-HNNXBMFYSA-N
- InChI
- 1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m0/s1
- Synonymes
- AC-30902 | F85017 | HY-50856A | Ruxolitinib S enantiomer | EX-A4005 | 1H-Pyrazole-1-propanenitrile, beta-cyclopentyl-...
- CrotonosideSolid ≥95%(HPLC)● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: C168062Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-2-one
- SMILES
- C1=NC2=C(NC(=O)N=C2N1C3C(C(C(O3)CO)O)O)N
- InChIKey
- MIKUYHXYGGJMLM-UUOKFMHZSA-N
- InChI
- 1S/C10H13N5O5/c11-7-4-8(14-10(19)13-7)15(2-12-4)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
- Synonymes
- 9H-Purin-2-ol, 6-amino-9-beta-D-ribofuranosyl- | Adenosine, 1,2-dihydro-2-oxo- | C08432 | 2-Oxo-3-hydroadenosine | 6-...
- SB1317, Tyrosine-protein kinase JAK2 inhibitorMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S127924Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (16E)-14-methyl-20-oxa-5,7,14,27-tetrazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2(27),3,5,8,10,12(26),16,21,23-decaene
- SMILES
- CN1CC=CCCOC2=CC=CC(=C2)C3=NC(=NC=C3)NC4=CC=CC(=C4)C1
- InChIKey
- VXBAJLGYBMTJCY-NSCUHMNNSA-N
- InChI
- show more
- Synonymes
- NSC762673 | NSC-762673 | EX-A7310 | 20-Oxa-5,7,14,27-tetraazatetracyclo[19.3.1.12,6.18,12]heptacosa-1(25),2,4,6(27),8...
- Tripolin A◐ .Sur commande · 8–12 semaines Article #: T275364Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- (3Z)-3-[(2,5-dihydroxyphenyl)methylidene]-1H-indol-2-one
- SMILES
- C1=CC=C2C(=C1)C(=CC3=C(C=CC(=C3)O)O)C(=O)N2
- InChIKey
- OMKSBDLWMROKNU-WQLSENKSSA-N
- InChI
- 1S/C15H11NO3/c17-10-5-6-14(18)9(7-10)8-12-11-3-1-2-4-13(11)16-15(12)19/h1-8,17-18H,(H,16,19)/b12-8-
- Synonymes
- (3Z)-3-[(2,5-Dihydroxyphenyl)methylidene]-1H-indol-2-one
- MS 436, Inhibitor of bromodomain containing 4CAS: 1395084-25-9 Formule: C18H17N5O3S Poids moléculaire: 383.42Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: M288001Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-[(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-pyridin-2-ylbenzenesulfonamide
- SMILES
- CC1=CC(=C(C=C1O)N)N=NC2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=N3
- InChIKey
- DZTGIRNXWSZBIM-UHFFFAOYSA-N
- InChI
- 1S/C18H17N5O3S/c1-12-10-16(15(19)11-17(12)24)22-21-13-5-7-14(8-6-13)27(25,26)23-18-4-2-3-9-20-18/h2-11,24H,19H2,1H3,(H,20,23)
- Synonymes
- (E)-4-[2-(2-Amino-4-hydroxy-5-methylphenyl)diazenyl]-N-2-pyridinylbenzenesulfonamide | MS436 | 4-[(2Z)-2-(2-amino-5-m...
- OAC1CAS: 300586-90-7 Formule: C14H11N3O Poids moléculaire: 237.26● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: O129631Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-(1H-pyrrolo[2,3-c]pyridin-5-yl)benzamide
- SMILES
- C1=CC=C(C=C1)C(=O)NC2=NC=C3C(=C2)C=CN3
- InChIKey
- HWJRIFZDXJKJJN-UHFFFAOYSA-N
- InChI
- 1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
- Synonymes
- OAC-1 | Oct4-activating Compound 1 | N-1H-Pyrrolo[2,3-c]pyridin-5-ylbenzamide
- SD 1008◐ .Sur commande · 8–12 semaines Article #: S288784Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- dimethyl (1R,5R,6R,7S)-8-benzyl-4-oxo-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylate
- SMILES
- COC(=O)C1C2C=CC(=O)C(C1C(=O)OC)N2CC3=CC=CC=C3
- InChIKey
- PYZQFEIRZQYUJQ-MIGQKNRLSA-N
- InChI
- 1S/C18H19NO5/c1-23-17(21)14-12-8-9-13(20)16(15(14)18(22)24-2)19(12)10-11-6-4-3-5-7-11/h3-9,12,14-16H,10H2,1-2H3/t12-,14-,15-,16+/m1/s1
- Synonymes
- rel-6,7-Dimethyl (1R,5R,6R,7S)-4-oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylate | HY-107595 | (1...
- GSK-J1, Inhibitor of lysine demethylase 5A;Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C;Inhibitor of lysine demethylase 6A;Inhibitor of lysine demethylase 6BMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G275049Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid
- SMILES
- C1CN(CCC2=CC=CC=C21)C3=NC(=NC(=C3)NCCC(=O)O)C4=CC=CC=N4
- InChIKey
- AVZCPICCWKMZDT-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- EX-A1744 | 3-((2-(Pyridin-2-yl)-6-(1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)pyrimidin-4-yl)amino)propanoic acid | 3-...
- PCI-34051Solid ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P126351Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
- SMILES
- COC1=CC=C(C=C1)CN2C=CC3=C2C=C(C=C3)C(=O)NO
- InChIKey
- AJRGHIGYPXNABY-UHFFFAOYSA-N
- InChI
- 1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)
- Synonymes
- N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide | BP-12358 | GKW | BDBM50397360 | CCG-267430 | HMS3604D11 |...
- MS023, Inhibitor of coactivator associated arginine methyltransferase 1;Inhibitor of protein arginine methyltransferase 1;Inhibitor of protein arginine methyltransferase 3;Inhibitor of protein arginine methyltransferase 6;Inhibitor of protein arginine methyltranCAS: 1831110-54-3 Formule: C17H25N3O Poids moléculaire: 287.4Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: M275329Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N'-methyl-N'-[[4-(4-propan-2-yloxyphenyl)-1H-pyrrol-3-yl]methyl]ethane-1,2-diamine
- SMILES
- CC(C)OC1=CC=C(C=C1)C2=CNC=C2CN(C)CCN
- InChIKey
- FMTVWAGUJRUAKE-UHFFFAOYSA-N
- InChI
- 1S/C17H25N3O/c1-13(2)21-16-6-4-14(5-7-16)17-11-19-10-15(17)12-20(3)9-8-18/h4-7,10-11,13,19H,8-9,12,18H2,1-3H3
- Synonymes
- N1-Methyl-N1-[[4-[4-(1-methylethoxy)phenyl]-1H-pyrrol-3-yl]methyl]-1,2-ethanediamine | N1-((4-(4-isopropoxyphenyl)-1H...
- BMS 911543, Tyrosine-protein kinase JAK2 inhibitorCAS: 1271022-90-2 Formule: C23H28N8O Poids moléculaire: 432.53Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: B345013Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,4,6,8,11-pentaene-11-carboxamide
- SMILES
- CCN1C(=CC2=C3C(=C(N=C21)NC4=NN(C(=C4)C)C)N=CN3C)C(=O)N(C5CC5)C6CC6
- InChIKey
- JCINBYQJBYJGDM-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- N,N-dicyclopropyl-7-[(1,5-dimethylpyrazol-3-yl)amino]-10-ethyl-3-methyl-3,5,8,10-tetrazatricyclo[7.3.0.02,6]dodeca-1,...
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Foire aux questions
What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which Epigenetics subcategory should I start with?
Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
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Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
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