Épigénétique

Découvrez des composés axés sur les voies métaboliques destinés à la recherche en épigénétique, notamment des outils liés à la régulation de la chromatine et au contrôle transcriptionnel. Utilisez cette page pour comparer les molécules employées dans les processus de validation des cibles, d'étude des mécanismes et de modulation de l'état cellulaire.

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  1. NSC 636819
    CAS: 1618672-71-1 Formule: C22H12Cl4N2O4 Poids moléculaire: 510.15
    ◐ .Sur commande · 8–12 semaines Article #: N288934
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    Nom IUPAC
    1,5-bis[(E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene
    SMILES
    C1=CC(=C(C=C1C=CC2=CC(=C(C=C2[N+](=O)[O-])[N+](=O)[O-])C=CC3=CC(=C(C=C3)Cl)Cl)Cl)Cl
    InChIKey
    YYZPXBXVBQSBDG-IJIVKGSJSA-N
    InChI
    1S/C22H12Cl4N2O4/c23-17-7-3-13(9-19(17)25)1-5-15-11-16(22(28(31)32)12-21(15)27(29)30)6-2-14-4-8-18(24)20(26)10-14/h1-12H/b5-1+,6-2+
    Synonymes
    1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene
  2. RSVA 405
    CAS: 140405-36-3 Numéro CE: 167-403-2 PubChem CID: 135400298 Formule: C17H20N4O2 Poids moléculaire: 312.37
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: R286690
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    Nom IUPAC
    N-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylideneamino]pyridine-4-carboxamide
    SMILES
    CCN(CC)C1=CC(=C(C=C1)C=NNC(=O)C2=CC=NC=C2)O
    InChIKey
    GWQPCBPAOAFXSJ-XDHOZWIPSA-N
    InChI
    1S/C17H20N4O2/c1-3-21(4-2)15-6-5-14(16(22)11-15)12-19-20-17(23)13-7-9-18-10-8-13/h5-12,22H,3-4H2,1-2H3,(H,20,23)/b19-12+
    Synonymes
    2-[[4-(Diethylamino)-2-hydroxyphenyl]methylene]hydrazide-4-pyridinecarboxylic acid
  3. Nicotinamide
    CAS: 98-92-0 Numéro CE: 202-713-4 Formule: C6H6N2O Poids moléculaire: 122.12
    Solid for Cell culture ? Cell-culture grade — low endotoxin and contaminants to support viable cell growth. Use in mammalian/other cell culture media and supplements. Suitable for insect cell culture ? Insect cell-culture grade — suited to insect cell systems (e.g. Sf9, baculovirus). Use for protein expression and culture in insect cell lines. ≥99.5%(HPLC)
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: N108087
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    Nom IUPAC
    pyridine-3-carboxamide
    SMILES
    C1=CC(=CN=C1)C(=O)N
    InChIKey
    DFPAKSUCGFBDDF-UHFFFAOYSA-N
    InChI
    1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
    Synonymes
    3-Pyridinecarboxylic acid amide | Delonin amide | niacinamide | Nicofort | vitamin PP | .beta.-Pyridinecarboxamide | ...
  4. Santacruzamate A, Inhibitor of histone deacetylase 2;Inhibitor of histone deacetylase 4;Inhibitor of histone deacetylase 6
    CAS: 1477949-42-0 PubChem CID: 72946782 Formule: C15H22N2O3 Poids moléculaire: 278.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S288868
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    Nom IUPAC
    ethyl N-[4-oxo-4-(2-phenylethylamino)butyl]carbamate
    SMILES
    CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1
    InChIKey
    HTOYBIILVCHURC-UHFFFAOYSA-N
    InChI
    1S/C15H22N2O3/c1-2-20-15(19)17-11-6-9-14(18)16-12-10-13-7-4-3-5-8-13/h3-5,7-8H,2,6,9-12H2,1H3,(H,16,18)(H,17,19)
    Synonymes
    ethyl N-{3-[(2-phenylethyl)carbamoyl]propyl}carbamate | HY-N0931 | santacruzamate A | GTPL7916 | NCGC00386359-03 | AK...
  5. Nicotinamide
    CAS: 98-92-0 Numéro CE: 202-713-4 Formule: C6H6N2O Poids moléculaire: 122.12
    Solid ≥99%
    ● En stock — Allemagne Article #: N105042
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    Identificateurs techniques
    Nom IUPAC
    pyridine-3-carboxamide
    SMILES
    C1=CC(=CN=C1)C(=O)N
    InChIKey
    DFPAKSUCGFBDDF-UHFFFAOYSA-N
    InChI
    1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
    Synonymes
    3-Pyridinecarboxylic acid amide | Delonin amide | niacinamide | Nicofort | vitamin PP | .beta.-Pyridinecarboxamide | ...
  6. Rocilinostat (ACY-1215), Histone deacetylase 6 inhibitor
    CAS: 1316214-52-4 Formule: C24H27N5O3 Poids moléculaire: 433.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: A124886
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    Nom IUPAC
    N-[7-(hydroxyamino)-7-oxoheptyl]-2-(N-phenylanilino)pyrimidine-5-carboxamide
    SMILES
    C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO
    InChIKey
    QGZYDVAGYRLSKP-UHFFFAOYSA-N
    InChI
    1S/C24H27N5O3/c30-22(28-32)15-9-1-2-10-16-25-23(31)19-17-26-24(27-18-19)29(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18,32H,1-2,9-10,15-16H2,(show more
    Synonymes
    HY-16026 | NCGC00345802-05 | AKOS024259260 | Ricolinostat [USAN] | BDBM50439674 | Ricolinostat (USAN/INN) | Rocilinos...
  7. Romidepsin (FK228, Depsipeptide), Histone deacetylase inhibitor
    CAS: 128517-07-7 PubChem CID: 5352062 Formule: C24H36N4O6S2 Poids moléculaire: 540.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: R125265
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    Nom IUPAC
    (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
    SMILES
    CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C
    InChIKey
    OHRURASPPZQGQM-GCCNXGTGSA-N
    InChI
    1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-show more
    Synonymes
    Methoxiphenadrinum | Depsipeptide | DEPSIPEPTIDE [WHO-DD] | Romidepsin (FK228) | Chromadax | L-Valine,3-didehydro-2- ...
  8. S 2101
    CAS: 1239262-36-2 PubChem CID: 121513887 Formule: C16H15F2NO.HCl Poids moléculaire: 311.75
    ◐ .Sur commande · 8–12 semaines Article #: S287634
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    Nom IUPAC
    (1R,2S)-2-(3,5-difluoro-2-phenylmethoxyphenyl)cyclopropan-1-amine;hydrochloride
    SMILES
    C1C(C1N)C2=C(C(=CC(=C2)F)F)OCC3=CC=CC=C3.Cl
    InChIKey
    CTSUZAFTJVLOIX-SBKWZQTDSA-N
    InChI
    1S/C16H15F2NO.ClH/c17-11-6-13(12-8-15(12)19)16(14(18)7-11)20-9-10-4-2-1-3-5-10;/h1-7,12,15H,8-9,19H2;1H/t12-,15+;/m0./s1
    Synonymes
    (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
  9. SAMS peptide
    CAS: 125911-68-4 PubChem CID: 71773161 Formule: C74H131N29O18S2 Poids moléculaire: 1779.15
    ◐ .Sur commande · 8–12 semaines Article #: S274821
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    Nom IUPAC
    (2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-(1H-imshow more
    SMILES
    CC(C)CC(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)CNC(=O)C(CO)NC(=O)C(CCSC)NC(=show more
    InChIKey
    YJAHUEAICBOBTC-CSVPVIMBSA-N
    InChI
    1S/C74H131N29O18S2/c1-38(2)27-51(66(115)100-53(30-43-32-84-37-90-43)67(116)99-52(28-39(3)4)68(117)103-57(40(5)6)70(119)97-45(15-10-11-21-75)61(110)95-show more
  10. PBIT, Inhibitor of lysine demethylase 5A;Inhibitor of lysine demethylase 5B;Inhibitor of lysine demethylase 5C
    CAS: 2514-30-9 Numéro CE: 841-911-0 PubChem CID: 935415 Formule: C14H11NOS Poids moléculaire: 241.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: P287387
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    Nom IUPAC
    2-(4-methylphenyl)-1,2-benzothiazol-3-one
    SMILES
    CC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3S2
    InChIKey
    KRXMYBAZKJBJAB-UHFFFAOYSA-N
    InChI
    1S/C14H11NOS/c1-10-6-8-11(9-7-10)15-14(16)12-4-2-3-5-13(12)17-15/h2-9H,1H3
    Synonymes
    Z275617084 | 2-(4-methylphenyl)-2,3-dihydro-1,2-benzothiazol-3-one | A14366 | ChemDiv3_007090 | BRD-K31634845-001-01-...
  11. SC-10
    CAS: 102649-79-6 PubChem CID: 5175 Formule: C17H22ClNO2S Poids moléculaire: 339.88
    ◐ .Sur commande · 8–12 semaines Article #: S275016
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    Nom IUPAC
    5-chloro-N-heptylnaphthalene-1-sulfonamide
    SMILES
    CCCCCCCNS(=O)(=O)C1=CC=CC2=C1C=CC=C2Cl
    InChIKey
    MJMJERJFCHYXEM-UHFFFAOYSA-N
    InChI
    1S/C17H22ClNO2S/c1-2-3-4-5-6-13-19-22(20,21)17-12-8-9-14-15(17)10-7-11-16(14)18/h7-12,19H,2-6,13H2,1H3
    Synonymes
    1-Naphthalenesulfonamide, 5-chloro-N-heptyl- | N-(m-Heptyl)-5-chloro-1-naphthalenesulfonamide | 5-chloro-N-heptylnaph...
  12. SGC-CBP30, Inhibitor of CREB binding protein;Inhibitor of E1A binding protein p300
    CAS: 1613695-14-9 Numéro CE: 106-820-6 PubChem CID: 72201027 Formule: C28H33ClN4O3 Poids moléculaire: 509.04
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S357869
    Voir le produit
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    Identificateurs techniques
    Nom IUPAC
    4-[(2S)-1-[2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]propan-2-yl]morpholine
    SMILES
    CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC(=C(C=C4)OC)Cl)CC(C)N5CCOCC5
    InChIKey
    GEPYBHCJBORHCE-SFHVURJKSA-N
    InChI
    1S/C28H33ClN4O3/c1-18(32-11-13-35-14-12-32)17-33-25-8-7-22(28-19(2)31-36-20(28)3)16-24(25)30-27(33)10-6-21-5-9-26(34-4)23(29)15-21/h5,7-9,15-16,18H,6,show more
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Foire aux questions

What should I consider when selecting an Epigenetics product?
Define the transformation first, then narrow the Epigenetics listing by reactivity, compatibility with your solvent and temperature window, and scale. Where several grades exist, the higher-purity option is usually worth it for downstream steps that are hard to purify.
Which Epigenetics subcategory should I start with?
Epigenetics is organised into AMPK, Aurora Kinase, DNA Methyltransferase, Epigenetic Reader Domain and Glycosyltransferase, and 17 further subcategories. Pick the subcategory that matches the structural motif or reaction class you need; compounds that fit more than one are cross-listed.
Which quality data should I check before ordering Epigenetics?
Review the lot-specific Certificate of Analysis for the Epigenetics product you have chosen: assay or HPLC purity, identity confirmation by NMR and MS, residual solvents where relevant, and appearance. For reactive or hygroscopic material the storage and handling notes matter as much as the purity figure. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
Can I search Epigenetics by structure or CAS number?
Yes. Within Epigenetics you can search by CAS number, molecular formula, or SMILES to reach exact structures and close analogs, and filter by functional group, purity grade, and pack size. For pricing, bulk quantities, or account eligibility, contact [email protected].

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