protéine kinase 3 activée par un mitogène
47 produits
Produits
- CP 43CAS: 850467-66-2 Formule: C25H24N2O2 Poids moléculaire: 384.4710mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: C426251Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide
- SMILES
- C1CC(C2=CC=CC=C2C1)NC(=O)CNC(=O)C3=CC=C(C=C3)C4=CC=CC=C4
- InChIKey
- WQKXOAJVNFOHNZ-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide
- CP 43CAS: 850467-66-2 Formule: C25H24N2O2 Poids moléculaire: 384.47● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: C287360Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-[2-oxo-2-(1,2,3,4-tetrahydronaphthalen-1-ylamino)ethyl]-4-phenylbenzamide
- SMILES
- C1CC(C2=CC=CC=C2C1)NC(=O)CNC(=O)C3=CC=C(C=C3)C4=CC=CC=C4
- InChIKey
- WQKXOAJVNFOHNZ-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- N-(2-Oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide | TAO Kinase inhibitor 1
- Demethyl-CoclaurineCAS: 5843-65-2 Formule: C16H17NO3 Poids moléculaire: 271.3110mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: D424889Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O
- InChIKey
- WZRCQWQRFZITDX-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
- Synonymes
- 6,7-Dihydroxy-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline | tris-(o-tolyl)phosphine | AC-26394 | FS-81...
- Demethyl-CoclaurineCAS: 5843-65-2 Formule: C16H17NO3 Poids moléculaire: 271.31● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: D412891Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O
- InChIKey
- WZRCQWQRFZITDX-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14/h1-4,8-9,14,17-20H,5-7H2
- Synonymes
- 6,7-Dihydroxy-1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline | tris-(o-tolyl)phosphine | AC-26394 | FS-81...
- GS-444217, Inhibitor of mitogen-activated protein kinase kinase kinase 5CAS: 1262041-49-5 Formule: C23H21N7O Poids moléculaire: 411.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G421098Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-(4-cyclopropylimidazol-1-yl)-N-[3-(4-cyclopropyl-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide
- SMILES
- C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6
- InChIKey
- ZGCMQKWOUIMBEP-UHFFFAOYSA-N
- InChI
- 1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31)
- Synonymes
- GS444217 | GS 444217 | ASK1-IN-1
- GSK 114CAS: 1301761-96-5 Formule: C19H23N5O4S Poids moléculaire: 417.48Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G412389Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 3-[(6,7-dimethoxyquinazolin-4-yl)amino]-4-(dimethylamino)-N-methylbenzenesulfonamide
- SMILES
- CNS(=O)(=O)C1=CC(=C(C=C1)N(C)C)NC2=NC=NC3=CC(=C(C=C32)OC)OC
- InChIKey
- YUSROMRPOFFTMX-UHFFFAOYSA-N
- InChI
- 1S/C19H23N5O4S/c1-20-29(25,26)12-6-7-16(24(2)3)15(8-12)23-19-13-9-17(27-4)18(28-5)10-14(13)21-11-22-19/h6-11,20H,1-5H3,(H,21,22,23)
- Synonymes
- GSK-114 | 3-((6,7-Dimethoxyquinazolin-4-yl)amino)-4-(dimethylamino)-N-methylbenzenesulfonamide
- GS-444217, Inhibitor of mitogen-activated protein kinase kinase kinase 5CAS: 1262041-49-5 Formule: C23H21N7O Poids moléculaire: 411.46Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: G412159Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 4-(4-cyclopropylimidazol-1-yl)-N-[3-(4-cyclopropyl-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide
- SMILES
- C1CC1C2=CN(C=N2)C3=CC(=NC=C3)C(=O)NC4=CC=CC(=C4)C5=NN=CN5C6CC6
- InChIKey
- ZGCMQKWOUIMBEP-UHFFFAOYSA-N
- InChI
- 1S/C23H21N7O/c31-23(20-11-19(8-9-24-20)29-12-21(25-13-29)15-4-5-15)27-17-3-1-2-16(10-17)22-28-26-14-30(22)18-6-7-18/h1-3,8-15,18H,4-7H2,(H,27,31)
- Synonymes
- GS444217 | GS 444217 | ASK1-IN-1
- Higenamine hydrochlorideCAS: 11041-94-4 Formule: C16H17NO3.HCl Poids moléculaire: 307.7710mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: H420598Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O.Cl
- InChIKey
- SWWQQSDRUYSMAR-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H
- Synonymes
- 6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)- | DTXSID10911673 | 6,7-d...
- Higenamine hydrochlorideSolid ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: H413084Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol;hydrochloride
- SMILES
- C1CNC(C2=CC(=C(C=C21)O)O)CC3=CC=C(C=C3)O.Cl
- InChIKey
- SWWQQSDRUYSMAR-UHFFFAOYSA-N
- InChI
- 1S/C16H17NO3.ClH/c18-12-3-1-10(2-4-12)7-14-13-9-16(20)15(19)8-11(13)5-6-17-14;/h1-4,8-9,14,17-20H,5-7H2;1H
- Synonymes
- 6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-1-((4-HYDROXYPHENYL)METHYL)-, HYDROCHLORIDE, (+/-)- | DTXSID10911673 | 6,7-d...
- N-Des(aminocarbonyl) AZ-TAK1 inhibitorCAS: 494772-87-1 Formule: C16H19N3O2S Poids moléculaire: 317.41◐ .Sur commande · 8–12 semaines Article #: D275539Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 3-amino-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide
- SMILES
- C1COCCN1CC2=CC=C(C=C2)C3=CC(=C(S3)C(=O)N)N
- InChIKey
- UNTPTSFVGRSTDC-UHFFFAOYSA-N
- InChI
- 1S/C16H19N3O2S/c17-13-9-14(22-15(13)16(18)20)12-3-1-11(2-4-12)10-19-5-7-21-8-6-19/h1-4,9H,5-8,10,17H2,(H2,18,20)
- Synonymes
- 3-Amino-5-[4-(morpholin-4-ylmethyl)phenyl]thiophene-2-carboxamide | N-Des(aminocarbonyl) AZ-TAK1 Inhibitor | starbld0...
- NG25, Inhibitor of C-terminal Src kinase;Inhibitor of LYN proto-oncogene; Src family tyrosine kinase;Inhibitor of mitogen-activated protein kinase kinase kinase 7;Inhibitor of mitogen-activated protein kinase kinase kinase kinase 2;Inhibitor of SRC proto-oncogeMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: N421221Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide
- SMILES
- CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=C5C=CNC5=NC=C4)C(F)(F)F
- InChIKey
- SMPGEBOIKULBCT-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- AC-35824 | Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]py...
- NQDI 1CAS: 175026-96-7 Formule: C19H13NO4 Poids moléculaire: 319.3110mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: N422144Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- ethyl 8,15-dioxo-14-azatetracyclo[7.7.1.02,7.013,17]heptadeca-1(16),2,4,6,9(17),10,12-heptaene-16-carboxylate
- SMILES
- CCOC(=O)C1=C2C3=CC=CC=C3C(=O)C4=C2C(=CC=C4)NC1=O
- InChIKey
- UFJGFNHRMPMALC-UHFFFAOYSA-N
- InChI
- 1S/C19H13NO4/c1-2-24-19(23)16-15-10-6-3-4-7-11(10)17(21)12-8-5-9-13(14(12)15)20-18(16)22/h3-9H,2H2,1H3,(H,20,22)
- Synonymes
- 2,7-Dihydro-2,7-dioxo-3H-naphtho[1,2,3-de]quinoline-1-carboxylic acid ethyl ester; ethyl 2,7-dioxo-3,7-dihydro-2H-nap...
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Foire aux questions
How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.