protéine kinase 3 activée par un mitogène
47 produits
Produits
- Selonsertib (GS-4997), Mitogen-activated protein kinase kinase kinase 5 inhibitorCAS: 1448428-04-3 Numéro CE: 822-332-2 PubChem CID: 71245288 Formule: C24H24FN7O Poids moléculaire: 445.49Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: S413964Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-(4-cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]benzamide
- SMILES
- CC1=CC(=C(C=C1N2C=C(N=C2)C3CC3)C(=O)NC4=CC=CC(=N4)C5=NN=CN5C(C)C)F
- InChIKey
- YIDDLAAKOYYGJG-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- AMY27913 | HY-18938 | 1448428-04-3 | (2S,SR)-METHIONINE SULFOXIMINE | EX-A1618 | GS 4997 | Selonsertib (GS-4997) | UN...
- Takinib, Inhibitor of CDC like kinase 2;Inhibitor of interleukin 1 receptor associated kinase 1;Inhibitor of interleukin 1 receptor associated kinase 4;Inhibitor of mitogen-activated protein kinase kinase kinase 7CAS: 1111556-37-6 Numéro CE: 841-675-9 PubChem CID: 37750349 Formule: C18H18N4O2 Poids moléculaire: 322.37Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● En stock — Entrepôt aux États-Unis, expédition vers l'EU* Article #: T420617Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 3-N-(1-propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
- SMILES
- CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
- InChIKey
- UOZVVPXKJGOFIG-UHFFFAOYSA-N
- InChI
- 1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
- Synonymes
- N17080 | SCHEMBL20063046 | F0918-1884 | A928060 | Tox21_300612 | Diethyl phthalate, 99% | NSC789624 | NSC-789624 | UN...
- pelubiprofenCAS: 69956-77-0 PubChem CID: 5282203Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Sur commande · 8–12 semaines Article #: P612684Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid
- SMILES
- CC(C1=CC=C(C=C1)C=C2CCCCC2=O)C(=O)O
- InChIKey
- AUZUGWXLBGZUPP-GXDHUFHOSA-N
- InChI
- 1S/C16H18O3/c1-11(16(18)19)13-8-6-12(7-9-13)10-14-4-2-3-5-15(14)17/h6-11H,2-5H2,1H3,(H,18,19)/b14-10+
- Synonymes
- (+-)-p-(((E)-2-Oxocyclohexylidene)methyl)hydratropic acid | CAS-69956-77-0 | DB12150 | Q27251763 | Benzeneacetic acid...
- Cot inhibitor-1◐ .Sur commande · 8–12 semaines Article #: C646885Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- PF-05381941CAS: 1474022-02-0 Formule: C27H26N6O2 Poids moléculaire: 466.53◐ .Sur commande · 8–12 semaines Article #: P647400Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- TAK1/MAP4K2 inhibitor 1◐ .Sur commande · 8–12 semaines Article #: T648184Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]benzamide
- SMILES
- CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=C4C=C(N5)C)C(F)(F)F
- InChIKey
- RWNAOXLCVXJMGM-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- AKOS016012030 | n-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-((6-methyl-7h-pyrrolo[2,3-...
- DLK-IN-1Solid ≥98%◐ .Sur commande · 8–12 semaines Article #: D650308Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 5-[5-[(1R,5S)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethoxy)pyridin-2-amine
- SMILES
- CC(C)N1C(=CC(=N1)C2=CC(=C(N=C2)N)OC(F)(F)F)C3C4C3CN(C4)C5COC5
- InChIKey
- UHEFRVBGJORHNV-UUVAVEHKSA-N
- InChI
- show more
- SM1-71◐ .Sur commande · 8–12 semaines Article #: S646519Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NC(=O)C=C)Cl
- InChIKey
- SCMLGVPMSXTUNC-UHFFFAOYSA-N
- InChI
- show more
- GNE-3511Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Sur commande · 8–12 semaines Article #: G647232Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile
- SMILES
- C1CN(CCC1C2=CC(=NC(=C2)N3CCC(C3)(F)F)NC4=NC=CC(=C4)C#N)C5COC5
- InChIKey
- RHFIAUKMKYHHFA-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- 2-((6-(3,3-Difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile
- ASK1-IN-2◐ .Sur commande · 8–12 semaines Article #: A648376Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 6-fluoro-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]-1H-indole-2-carboxamide
- SMILES
- CC(C)N1C=NN=C1C2=NC(=CC=C2)NC(=O)C3=CC4=C(N3)C=C(C=C4)F
- InChIKey
- LYUQNMNUBOUCBX-UHFFFAOYSA-N
- InChI
- 1S/C19H17FN6O/c1-11(2)26-10-21-25-18(26)14-4-3-5-17(23-14)24-19(27)16-8-12-6-7-13(20)9-15(12)22-16/h3-11,22H,1-2H3,(H,23,24,27)
- TAK1-IN-4CAS: 1570374-32-1 Formule: C18H17N3O3 Poids moléculaire: 323.35◐ .Sur commande · 8–12 semaines Article #: T649901Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- SMILES
- O=C(C1=CC=CC(C(NC2=NC3=C(N2CCC)C=CC=C3)=O)=C1)O
- Cot inhibitor-2◐ .Sur commande · 8–12 semaines Article #: C650545Voir le produitTarifs et tailles des emballages
Identificateurs techniques
- Nom IUPAC
- 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-carbonitrile
- SMILES
- CCN1CCC(CC1)N2C=C(N=N2)CNC3=CC4=C(C(=CN=C4C(=C3)Cl)C#N)NC5=CC(=C(C=C5)F)Cl
- InChIKey
- PHNZIIMWDVXPGG-UHFFFAOYSA-N
- InChI
- show more
- Synonymes
- BDBM29923 | 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-c...
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Foire aux questions
How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.