≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
NL-1 is an inhibitor of mitoNEET with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50 of 47.35 µM and 56.26 µM, respectively.
| Pubchem Sid | 528766289 |
|---|---|
| Sourires canoniques | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC2C(=O)NC(=O)S2 |
| IUPAC Name | 5-[(3,5-ditert-butyl-4-hydroxyphenyl)methyl]-1,3-thiazolidine-2,4-dione |
| InChIKey | QDYYSPGKYXWGSL-UHFFFAOYSA-N |
| INCHI | 1S/C18H25NO3S/c1-17(2,3)11-7-10(8-12(14(11)20)18(4,5)6)9-13-15(21)19-16(22)23-13/h7-8,13,20H,9H2,1-6H3,(H,19,21,22) |
| Isomères SMILES | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC2C(=O)NC(=O)S2 |
| Poids moléculaire | 335.46 |
| Reaxy-Rn | 8570390 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8570390&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Classe | Benzene and substituted derivatives |
| Subclass | Phenylpropanes |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpropanes |
| Alternative Parents | Thiazolidinediones Phenols Dicarboximides Thiocarbamic acid derivatives Azacyclic compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Phenylpropane - Phenol - Thiazolidinedione - Dicarboximide - Thiazolidine - Thiocarbamic acid derivative - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic oxide - Organic oxygen compound - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Carbonyl group - Aromatic heteromonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as phenylpropanes. These are organic compounds containing a phenylpropane moiety. |
| External Descriptors | Not available |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Article |
|---|---|---|---|
 B24231006 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423866 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423869 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423870 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423871 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423878 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423879 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423880 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423881 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| B2423885 | Certificate of Analysis | Jan 12, 2024 | N412534 |
| Solubilité | DMSO: 250 mg/mL (745.25 mM), Need ultrasonic( < 1 mg/mL refers to the product slightly soluble or insoluble ) |
|---|---|
| Poids moléculaire | 335.500 g/mol |
| XLogP3 | 5.000 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 4 |
| Exact Mass | 335.156 Da |
| Monoisotopic Mass | 335.156 Da |
| Topological Polar Surface Area | 91.700 Ų |
| Heavy Atom Count | 23 |
| Formal Charge | 0 |
| Complexity | 454.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
