Ravulizumab (anti-Complement C5) - Anticorps primaire, specific to C5, >95%, Human IgG2, INHIBITOR of Complement C5 inhibitor, INHIBITOR of Complement C5 inhibitor

CAS: 1803171-55-2 Cat. No.: Ab176615

QUALITÉ & PURETÉ Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Humain

Reactive species

Humain, Rhesus monkey, Singe cynomolgus, Souris

Isotype

Human IgG2

Conjugation

Unconjugated

Vue d’ensemble

Ravulizumab (anti-Complement C5) is a humanized monoclonal antibody that specifically binds with high affinity to the human complement protein C5. Ravulizumab (anti-Complement C5) can be used for the research of paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, and myasthenia gravis.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Spécifications

Product Name

Ravulizumab (anti-Complement C5) - Anticorps primaire, specific to C5, >95%, Human IgG2, INHIBITOR of Complement C5 inhibitor

Synonymes

Anaphylatoxin C5a analog antibody | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4 antibody | C5 antibody | C5a anaphylatoxin antibody | C5a antibody | C5b antibody | CO5_HUMAN antibody | Complement C5 alpha'' chain antibody | Complemen

Spécifications et pureté

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Espèce hôte

Humain

Spécificité

C5

Conjugation

Unconjugated

Grade

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Type d'action

INHIBITOR

Mécanisme d'action

INHIBITOR of Complement C5 inhibitor

Isotype

Human IgG2

Type de chaîne lumineuse

kappa

SDS-PAGE

145.80 kDa

Méthode de purification

Protein A purified

La pureté

>95%

Concentration

See COA

CAS

1803171-55-2

Product Line

Produits biologiques

Stockage et expédition

Forme

Liquid

Conditions de stockage de stockage

Store at -80°C,Avoid repeated freezing and thawing

Expédié en

Dry ice packs + Cold packs

Stabilité et stockage

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Images

SEC: Ravulizumab (anti-Complement C5) (Ab176615)

Ravulizumab (anti-Complement C5) (Ab176615) - SEC
The purity of Ravulizumab (anti-Complement C5) (Ab176615) is more than 95% verified by HPLC.

Cibles associées (humaines)

C5 Tclin Complement C5 (0 Activities)

Discover Target: C5

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Mécanismes d'action

Foire aux questions

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1803171-55-2.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Ravulizumab (anti-Complement C5)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.