Sinefungin - Moligand™, 10 mM in Water , CAS No.58944-73-3

CAS: 58944-73-3 Cat. No.: S1493491 Formule: C₁₅H₂₃N₇O₅ Poids moléculaire: 381.39 Numéro CE: 637-385-5 PubChem CID: 65482

GRADE & PURITY Moligand™, 10 mM in Water

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Vue d’ensemble

Sinefungin is a potent inhibitor of virion mRNA (guanine-7-)-methyltransferase, mRNA (nucleoside-2'-)-methyltransferase , and viral multiplication. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation.

Specifications

Spécifications et pureté

Moligand™, 10 mM in Water

Conditions de stockage de stockage

Store at -80°C

Expédié en

Dry ice packs + Cold packs

Ce produit nécessite l'expédition en chaîne froide. Les services terrestres et autres services économiques ne sont pas disponibles.

Grade

Moligand™

Noms et identifiants

• Isomères SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)C[C@H](CC[C@@H](C(=O)O)N)N)O)O)N
• WGK Allemagne: 3
• RTECS: HE3140000
• PubChem CID: 65482
• Poids moléculaire: 381.39

Références

1. Rui-Li Zhu, Ying-Kun Zhi, Lang Yi, Jin-Fang Luo, Jing Li, Sha-Sha Bai, Liang Liu, Pei-Xun Wang, Hua Zhou, Yan Dong.  (2019)  Sinomenine regulates CD14/TLR4, JAK2/STAT3 pathway and calcium signal via α7nAChR to inhibit inflammation in LPS-stimulated macrophages.  IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY,      [PMID:30896303] [10.1080/08923973.2019.1568451]

2. Lang Yi, Yan-jun Lyn, Chong Peng, Rui-li Zhu, Sha-sha Bai, Liang Liu, Pei-xun Wang, Hua Zhou, Yan Dong.  (2018)  Sinomenine inhibits fibroblast-like synoviocyte proliferation by regulating α7nAChR expression via ERK/Egr-1 pathway.  INTERNATIONAL IMMUNOPHARMACOLOGY,      [PMID:29367088] [10.1016/j.intimp.2018.01.015]

3. Biao Zhou, Xiaolong Lu, Zhi Tang, Dan Liu, Youliang Zhou, Peng Zeng, Hui Xiong.  (2017)  Influence of sinomenine upon mesenchymal stem cells in osteoclastogenesis.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:28437887] [10.1016/j.biopha.2017.03.084]

Foire aux questions

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 58944-73-3, the molecular formula is C15H23N7O5, and the molecular weight is 381.39 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.