Abelacimab (anti-Factor XI) - Anticorpo primario, specific to F11, >95%, Human IgG1, Antibody of integrin αIIbβ3, Antibody of integrin αIIbβ3

CAS: 2098724-83-3 Cat. No.: Ab175444
Disponibile su ordine
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ≥95%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Umano
Reactive species
Umano
Isotype
Human IgG1
Conjugation
Unconjugated
★
Size
Germania (EU)
USA*
Price
Qty
100μg
Ab175444-100μg
—
Disponibile ≥10
104,04€
1mg
Ab175444-1mg
—
4 Disponibile
520,56€
5mg
Ab175444-5mg
—
1 Disponibile
950,96€
10mg
Ab175444-10mg
Su ordinazione · 8–12 settimane
1.514,99€
Enter a quantity for the sizes you want to add.
🧪
Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Panoramica

Abelacimab (anti-Factor XI) is a fully human IgG1 monoclonal antibody that binds with high affinity to the catalytic structural domain of FXI and locks it in the zymogen conformation, thereby preventing its activation by FXIIa or thrombin. Abelacimab (anti-Factor XI) can be used in thromboembolic disease studies.

Specifications

Product Name
Abelacimab (anti-Factor XI) - Anticorpo primario, specific to F11, >95%, Human IgG1, Antibody of integrin αIIbβ3
Sinonimi
coagulation factor XI antibody | Coagulation factor XIa light chain antibody | F11 antibody | FA11_HUMAN antibody | FXI antibody | MGC141891 antibody | Plasma thromboplastin antecedent antibody | Platelet coagulation factor XI antibody | PTA antibody | Co
Specifiche e purezza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA
Meccanismi biochimici e fisiologici
Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX.
Specie ospite
Umano
Specificità
F11
Coniugazione
Unconjugated
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo di azione
INHIBITOR
Meccanismo d'azione
Antibody of integrin αIIbβ3
Isotipo
Human IgG1
Tipo di catena leggera
lambda
SDS-PAGE
27.4 kDa (Light Chain) & 50.4 kDa (Heavy Chain), under reducing conditions; 197.4kDa, under non-reducing conditions.
Metodo di purificazione
Protein A purified
La purezza
>95%
Concentrazione
See COA
CAS
2098724-83-3
Product Line
Prodotti biologici
Stoccaggio e spedizione
Forma
Liquid
Condizioni di conservazione di stoccaggio
Store at -80°C,Avoid repeated freezing and thawing
Spedito in
Dry ice packs + Cold packs
Stabilità e conservazione
Store at -80℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Immagini

Abelacimab (anti-Factor XI) (Ab175444) - SEC
The purity of Abelacimab (anti-Factor XI) (Ab175444) is more than 95% verified by HPLC.

Abelacimab (anti-Factor XI) (Ab175444) - ELISA
Immobilized Human F11-his at 2.0 μg/mL can bind Abelacimab (anti-Factor XI) (Ab175444) with the EC₅₀ of 31.79 ng/mL.

Documentazione

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Obiettivi associati (umani)
F11 Tchem Coagulation factor XI (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGA2B Tclin Integrin alpha-IIb (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGB3 Tclin Integrin beta-3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ITGA2B Tclin Integrin alpha-IIb (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
F11 Tchem Coagulation factor XI (1733 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 (2708 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-IIb/beta-3 (3481 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Fibronectin receptor (Integrin alpha-5/beta-1 and alpha-V/beta-3) (39 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-V/beta-3 and alpha-IIb/beta 3 (49 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-2/beta-3 (21 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ITGB3 Tclin Integrin alpha-3/beta-3 (47 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Meccanismi d'azione
Certificati (CoA, COO, BSE/TSE e tabella di analisi)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDataOggetto
ZJ24F0607383Certificate of AnalysisJun 26, 2024 Ab175444
ZJ24F0202895Certificate of AnalysisMar 01, 2024 Ab175444
ZJ24F0202894Certificate of AnalysisMar 01, 2024 Ab175444
ZJ24F0202893Certificate of AnalysisMar 01, 2024 Ab175444
Calcolatori di soluzioni
Recensioni

Recensioni dei clienti

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →

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