Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Crovalimab (anti-Complement C5) is a novel humanized antibody against C5 in a pH-dependent manner with KDs of 15.2 nM and 16.8 μM at pH 7.4 and 5.8, respectively. Crovalimab (anti-Complement C5) binds human FcRn with great affinity (KD: 17 μM at pH 6.0). Crovalimab (anti-Complement C5) can block cleavage of C5 by the C5 convertase and inhibite the activity of a C5 variant (p.Arg885His). Crovalimab (anti-Complement C5) inhibits C5b-9 formation significantly in all three complement pathways, the classical pathway (CP), lectin pathway (LP), and alternative pathway (AP). Crovalimab (anti-Complement C5) has the potential for paroxysmal nocturnal hemoglobinuria (PNH) and complement-mediated diseases research.
Purity
>95% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg
Crovalimab (anti-Complement C5) (Ab182862) - ELISA
Immobilized Human Complement C5 Protein at 2.0 μg/mL can bind Crovalimab (anti-Complement C5) (Ab182862) with the EC50 of 9.58 ng/mL.
Crovalimab (anti-Complement C5) (Ab182862) - SEC
The purity of Crovalimab (anti-Complement C5) (Ab182862) is more than 95% verified by HPLC.
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0606987 | Certificate of Analysis | Apr 16, 2026 | Ab182862 |
| ZJ24F0606988 | Certificate of Analysis | Apr 16, 2026 | Ab182862 |
| ZJ24F0606989 | Certificate of Analysis | Apr 16, 2026 | Ab182862 |
| ZJ26F0433780 | Certificate of Analysis | Apr 03, 2026 | Ab182862 |
| ZJ26F0433779 | Certificate of Analysis | Apr 03, 2026 | Ab182862 |
| ZJ26F0433778 | Certificate of Analysis | Apr 03, 2026 | Ab182862 |
| ZJ25F0927252 | Certificate of Analysis | Sep 16, 2025 | Ab182862 |
| ZJ25F0927251 | Certificate of Analysis | Sep 16, 2025 | Ab182862 |
| ZJ25F0927250 | Certificate of Analysis | Sep 16, 2025 | Ab182862 |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Animal Free grade guide → View Carrier Free grade guide → View Recombinant grade guide → View Validated grade guide → View ExactAb™ grade guide → View Low Endotoxin grade guide → View Azide Free grade guide →
