1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
The core value of classical histological special staining is to further distinguish structures such as muscle fibers, collagen fibers, elastic fibers, reticular fibers, fibrin, and neuroglial fibers on the basis of HE staining. PTAH, Masson, VG, elastic fiber staining, and reticular fiber ...
Urinary protein biomarker detection is used to determine the source of proteinuria, the degree of filtration barrier injury, and whether tubular injury is also present. Albumin, transferrin, IgG, and α2-macroglobulin differ in molecular size and in the conditions under which they enter urine. ...
The cytoskeleton is a dynamic fibrous network composed of microfilaments, microtubules, and intermediate filaments, mainly consisting of actin, tubulin, and different types of intermediate filament proteins. The cytoskeleton not only maintains cell morphology, cell polarity, and intracellular ...
The endocrine system maintains body homeostasis through hormone secretion, target organ responses, and feedback regulation. Hormones regulate glucose and lipid metabolism, growth and development, reproductive function, stress responses, water and electrolyte balance, bone metabolism, and energy ...
RNA-DNA hybrids are nucleic acid structures formed by pairing between an RNA strand and a DNA template strand. Typical forms include transcription-associated R-loops and hybrid regions formed after ribonucleotides are incorporated into DNA. RNase H1, RNase H2, helicases, topoisomerases, and ...
RNA structure analysis often requires distinguishing single-stranded regions, double-stranded regions, stacked regions, and differences in structural accessibility. RNase T1, RNase A, RNase V1, and S1 nuclease can be used as structural probes. By selectively cleaving different conformational or ...
In Alzheimer’s disease models, cholinergic detection should not focus only on measuring acetylcholine or acetylcholinesterase separately. The key is to assess the relationship among neurotransmitter levels, enzyme activity changes, cholinergic neuronal injury, and inflammatory responses. When ...
Apolipoproteins (Apos) are important protein components of lipoprotein particles. They participate in the transport of triglycerides, cholesterol, phospholipids, and lipid-soluble molecules, and determine the interactions between lipoproteins and receptors, enzymes, and transport proteins.
Autophagy is a cellular quality control system that delivers cytoplasmic components, damaged organelles, protein aggregates, or intracellular pathogens to lysosomes for degradation. Its core significance is not simply “increased degradation,” but rather the maintenance of cellular ...