Iparomlimab (anti-PDCD1) - Primary antibody, specific to PDCD1, Human IgG4SP

CAS: 2417649-33-1 Cat. No.: Ab190143

GRADE & PURITY Animal Free, Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

Human

Reactive species

Human

Isotype

Human IgG4SP

Conjugation

Unconjugated

Visão geral

Iparomlimab (anti-PDCD1) is a human IgG4κ monoclonal antibody targated against PD-1/CD279/PDCD1. Iparomlimab (anti-PDCD1) can be used for oncology research.

Specifications

Product Name

Iparomlimab (anti-PDCD1) - Primary antibody, specific to PDCD1, Human IgG4SP

Sinónimos

CD279 antibody | CD279 antigen antibody | hPD 1 antibody | hPD l antibody | hPD-1 antibody | hSLE1 antibody | PD 1 antibody | PD-1 antibody | PD1 antibody | PDCD 1 antibody | PDCD1 antibody | PDCD1_HUMAN antibody | Programmed cell death 1 antibody | Progr

Especificações e pureza

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Mecanismos bioquímicos e fisiológicos

Possible cell death inducer, in association with other factors.

Espécie hospedeira

Human

Especificidade

PDCD1

Conjugação

Unconjugated

Grau

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

Tipo de ação

INHIBITOR

Isótipo

Human IgG4SP

Tipo de corrente de luz

kappa

SDS-PAGE

145 kDa

Método de purificação

Protein A purified

Concentração

See COA

CAS

2417649-33-1

Product Line

Produtos biológicos

Armazenamento e envio

Condições de armazenamento de armazenamento

Store at -80°C,Avoid repeated freezing and thawing

Enviado em

Dry ice packs + Cold packs

Estabilidade e armazenamento

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Imagens

Flow Cytometry: Iparomlimab (anti-PDCD1) (Ab190143)

Iparomlimab (anti-PDCD1) (Ab190143) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PDCD1 (red) with Iparomlimab (anti-PDCD1) (Ab190143) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Iparomlimab (anti-PDCD1) (Ab190143)

Iparomlimab (anti-PDCD1) (Ab190143) - ELISA
Immobilized Recombinant Human PD-1 protein (rp176241) at 1.0 μg/mL can bind Iparomlimab (anti-PDCD1) (Ab190143) with the EC₅₀ of 61.89 ng/mL.

SEC: Iparomlimab (anti-PDCD1) (Ab190143)

Iparomlimab (anti-PDCD1) (Ab190143) - SEC
The purity of Iparomlimab (anti-PDCD1) (Ab190143) is more than 95% verified by HPLC.

Alvos associados (humanos)

PDCD1 Tclin Programmed cell death protein 1 (0 Activities)

Discover Target: PDCD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDCD1 Tclin Programmed cell death protein 1 (14 Activities)

Discover Target: PDCD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Perguntas frequentes

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2417649-33-1.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Iparomlimab (anti-PDCD1)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.