GSK-3

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  1. GSK3β inhibitor II, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 478482-75-6 Fórmula: C14H10IN3OS Peso molecular: 395.22
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: G338641
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    Nome IUPAC
    2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole
    SMILES
    C1=CC(=CC(=C1)I)CSC2=NN=C(O2)C3=CC=NC=C3
    InChIKey
    ZRHRPGSSSVYBRG-UHFFFAOYSA-N
    InChI
    1S/C14H10IN3OS/c15-12-3-1-2-10(8-12)9-20-14-18-17-13(19-14)11-4-6-16-7-5-11/h1-8H,9H2
    Sinónimos
    2-Thio(3-iodobenzyl)-5-(1-pyridyl)-[1,3,4]-oxadiazole | 2-{[(3-iodophenyl)methyl]sulfanyl}-5-(pyridin-4-yl)-1,3,4-oxa...
  2. Lithium chloride monohydrate
    CAS: 85144-11-2 Fórmula: LiCI·H2O Peso molecular: 60.41
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: L118859
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    Nome IUPAC
    lithium;chloride;hydrate
    SMILES
    [Li+].O.[Cl-]
    InChIKey
    VXJIMUZIBHBWBV-UHFFFAOYSA-M
    InChI
    1S/ClH.Li.H2O/h1H;;1H2/q;+1;/p-1
    Sinónimos
    AKOS015855094 | Lithium chloride hydrate, Puratronic? | lithium;chloride;hydrate | Lithium chloride, monohydrate (8CI...
  3. LY2090314, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 603288-22-8 Número CE: 110-218-9 Fórmula: C28H25FN6O3 Peso molecular: 512.53
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: L126079
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    Nome IUPAC
    3-[6-fluoro-10-(piperidine-1-carbonyl)-1,10-diazatricyclo[6.4.1.04,13]trideca-2,4,6,8(13)-tetraen-3-yl]-4-imidazo[1,2-a]pyridin-3-ylpyrrole-2,5-dione
    SMILES
    C1CCN(CC1)C(=O)N2CCN3C=C(C4=CC(=CC(=C43)C2)F)C5=C(C(=O)NC5=O)C6=CN=C7N6C=CC=C7
    InChIKey
    HRJWTAWVFDCTGO-UHFFFAOYSA-N
    InChI
    1S/C28H25FN6O3/c29-18-12-17-15-34(28(38)32-7-3-1-4-8-32)11-10-33-16-20(19(13-18)25(17)33)23-24(27(37)31-26(23)36)21-14-30-22-6-2-5-9-35(21)22/h2,5-6,9show more
    Sinónimos
    ?-(Trichloromethyl)-4-pyridineethanol | AS-56097 | Kinome_3681 | LY2090314 | LY-2090314 | LY 2090314 | NSC801005 | NS...
  4. TWS 119
    CAS: 1507095-58-0 PubChem CID: 90488884 Fórmula: C22H16F6N4O6 Peso molecular: 546.38
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: T288232
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    Nome IUPAC
    3-[[6-(3-aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenol;2,2,2-trifluoroacetic acid
    SMILES
    C1=CC(=CC(=C1)N)C2=CC3=C(N2)N=CN=C3OC4=CC=CC(=C4)O.C(=O)(C(F)(F)F)O.C(=O)(C(F)(F)F)O
    InChIKey
    XJEFPMFFWJTJSL-UHFFFAOYSA-N
    InChI
    1S/C18H14N4O2.2C2HF3O2/c19-12-4-1-3-11(7-12)16-9-15-17(22-16)20-10-21-18(15)24-14-6-2-5-13(23)8-14;2*3-2(4,5)1(6)7/h1-10,23H,19H2,(H,20,21,22);2*(H,6,show more
    Sinónimos
    3-[[6-(3-Aminophenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxyphenol ditrifluoroacetate
  5. 2B-(SP) (TFA)
    CAS: 186901-17-7 PubChem CID: 90488714 Fórmula: C71H123N26O29P Peso molecular: 1835.88 (free base basis)
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: B287641
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    Nome IUPAC
    (2S)-2-[[(2S)-5-amino-2-[[(2S)-1-[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-show more
    SMILES
    CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NCC(=O)NC(COP(=O)(O)O)C(=O)N1CCCC1C(=O)NC(CCC(=O)N)C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(show more
    InChIKey
    LBVCQYQHTKHZRY-APZQELAWSA-N
    InChI
    1S/C71H123N26O29P/c1-32(2)26-43(93-61(114)42(18-21-52(103)104)91-60(113)41(17-20-51(101)102)88-56(109)36(7)84-55(108)35(6)86-58(111)38(13-9-23-81-70(7show more
  6. R547, Cyclin-dependent kinase 4 inhibitor
    CAS: 741713-40-6 PubChem CID: 6918852 Fórmula: C18H21F2N5O4S Peso molecular: 441.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: R127351
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    Nome IUPAC
    [4-amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl]-(2,3-difluoro-6-methoxyphenyl)methanone
    SMILES
    COC1=C(C(=C(C=C1)F)F)C(=O)C2=CN=C(N=C2N)NC3CCN(CC3)S(=O)(=O)C
    InChIKey
    JRNJNYBQQYBCLE-UHFFFAOYSA-N
    InChI
    1S/C18H21F2N5O4S/c1-29-13-4-3-12(19)15(20)14(13)16(26)11-9-22-18(24-17(11)21)23-10-5-7-25(8-6-10)30(2,27)28/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24)
    Sinónimos
    (4-amino-2-(1-(methylsulfonyl)piperidin-4-ylamino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone | (4-Amino-2...
  7. AR-A014418, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 487021-52-3 Número CE: 637-170-6 Fórmula: C12H12N4O4S Peso molecular: 308.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: A126821
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    Nome IUPAC
    1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea
    SMILES
    COC1=CC=C(C=C1)CNC(=O)NC2=NC=C(S2)[N+](=O)[O-]
    InChIKey
    YAEMHJKFIIIULI-UHFFFAOYSA-N
    InChI
    1S/C12H12N4O4S/c1-20-9-4-2-8(3-5-9)6-13-11(17)15-12-14-7-10(21-12)16(18)19/h2-5,7H,6H2,1H3,(H2,13,14,15,17)
    Sinónimos
    AM803946 | GSK 3b inhibitor VIII | Q27077900 | BDBM50229962 | 1276635-87-0 | AR-A014418, >=98% (HPLC), solid | GSK-3b...
  8. AZD2858, Inhibitor of glycogen synthase kinase 3 beta
    CAS: 486424-20-8 Número CE: 690-692-6 Fórmula: C21H23N7O3S Peso molecular: 453.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: A126819
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    Nome IUPAC
    3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide
    SMILES
    CN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N
    InChIKey
    FHCSBLWRGCOVPT-UHFFFAOYSA-N
    InChI
    1S/C21H23N7O3S/c1-27-9-11-28(12-10-27)32(30,31)17-6-4-15(5-7-17)18-14-24-20(22)19(26-18)21(29)25-16-3-2-8-23-13-16/h2-8,13-14H,9-12H2,1H3,(H2,22,24)(Hshow more
    Sinónimos
    A871895 | 3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-N-3-pyridinyl-2-pyrazinecarboxamide | AC-30277 | 3-a...
  9. AZD1080, Inhibitor of glycogen synthase kinase 3 alpha;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 612487-72-6 Fórmula: C19H18N4O2 Peso molecular: 334.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: A126905
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    Nome IUPAC
    2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]-1H-indole-5-carbonitrile
    SMILES
    C1COCCN1CC2=CN=C(C=C2)C3=C(NC4=C3C=C(C=C4)C#N)O
    InChIKey
    BLTVBQXJFVRPFK-UHFFFAOYSA-N
    InChI
    1S/C19H18N4O2/c20-10-13-1-3-16-15(9-13)18(19(24)22-16)17-4-2-14(11-21-17)12-23-5-7-25-8-6-23/h1-4,9,11,22,24H,5-8,12H2
    Sinónimos
    1,3-DICHLOROPROPENE, (1E)- | 2-hydroxy-3-(5-(morpholinomethyl)pyridin-2-yl)-1H-indole-5-carbonitrile | AKOS026674123 ...
  10. Alsterpaullone, Inhibitor of cyclin dependent kinase 1;Inhibitor of glycogen synthase kinase 3 beta
    CAS: 237430-03-4 Número CE: 636-614-6 Fórmula: C16H11N3O3 Peso molecular: 293.28
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: A274619
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    Nome IUPAC
    9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one
    SMILES
    C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-]
    InChIKey
    OLUKILHGKRVDCT-UHFFFAOYSA-N
    InChI
    1S/C16H11N3O3/c20-15-8-12-11-7-9(19(21)22)5-6-14(11)18-16(12)10-3-1-2-4-13(10)17-15/h1-7,18H,8H2,(H,17,20)
    Sinónimos
    BDBM7262 | EX-A4771 | HMS2043P15 | 9-nitro-7,12-dihydro-5H-indolo[3,2-d][1]benzazepin-6-one | J-015199 | BRD-K1751638...
  11. Indazole
    CAS: 271-44-3 Número CE: 205-978-4 Fórmula: C7H6N2 Peso molecular: 118.14
    ● Em estoque — Armazém nos EUA, envio para a EU* Item #: I157585
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    Nome IUPAC
    1H-indazole
    SMILES
    C1=CC=C2C(=C1)C=NN2
    InChIKey
    BAXOFTOLAUCFNW-UHFFFAOYSA-N
    InChI
    1S/C7H6N2/c1-2-4-7-6(3-1)5-8-9-7/h1-5H,(H,8,9)
    Sinónimos
    1,2-Benzopyrazole | F0918-7060 | F1918-0009 | Indazole, 6 | UNII-7C4VQE5C03 | 1H-indazol | EINECS 205-978-4 | FT-0627...
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Perguntas frequentes

Which compounds are listed for GSK-3?
Compounds associated with GSK-3 are grouped here under the Stem Cell/Wnt classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.
How does GSK-3 sit within Stem Cell/Wnt?
GSK-3 is one target listing within the Stem Cell/Wnt classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.
What data should I check before ordering a compound from GSK-3?
For compounds listed under GSK-3, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
How do I find related targets or backup compounds for GSK-3?
Browse the parent Stem Cell/Wnt listing to reach targets neighbouring GSK-3, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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