10-Formyl Folic Acid - ≥95% , CAS No.134-05-4

CAS: 134-05-4 Cat. No.: F334434 Peso molecular: 469.41 Número EC: 801-529-7

GRADE & PURITY ≥95%

Synonyms

10-Formylpteroylglutamic Acid | 10-Formyldihydropteroylglutamate | L-GLUTAMIC ACID, N-(4-(((2-AMINO-3,4-DIHYDRO-4-OXO-6-PTERIDINYL)METHYL)FORMYLAMINO)BENZOYL)- | UGWUWNVTCLDEOG-ZDUSSCGKSA-N | L-Glutamic acid, N-(4-(((2-amino-1,4,?,?-tetrahydro-4-oxo-6-pte

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

10-Formyl Folic Acid is a Folic Acid derivative (or folate) found in daily dietary intake that is often used in cancer risk correlation studies.

Specifications

Sinónimos

10-Formylpteroylglutamic Acid | 10-Formyldihydropteroylglutamate | L-GLUTAMIC ACID, N-(4-(((2-AMINO-3, 4-DIHYDRO-4-OXO-6-PTERIDINYL)METHYL)FORMYLAMINO)BENZOYL)- | UGWUWNVTCLDEOG-ZDUSSCGKSA-N | L-Glutamic acid, N-(4-(((2-amino-1, 4, ?, ?-tetrahydro-4-oxo-6-pte

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥95%

Nombres e identificadores

• Sonrisas canónicas: C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)N(CC2=CN=C3C(=N2)C(=O)NC(=N3)N)C=O
• IUPAC Name: (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
• InChIKey: UGWUWNVTCLDEOG-ZDUSSCGKSA-N
• INCHI: 1S/C20H19N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,7,9,13H,5-6,8H2,(H,24,31)(H,29,30)(H,33,34)(H3,21,22,25,26,32)/t13-/m0/s1
• Isómeros SMILES: C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)N(CC2=CN=C3C(=N2)C(=O)NC(=N3)N)C=O
• Peso molecular: 469.41
• Reaxy-Rn: 15056230
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=15056230&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Pteridines and derivatives
      • Subclass Pterins and derivatives
        • Level5 Pteroic acids and derivatives
          • Level6 Folic acids and derivatives
            • Level7 Folic acids

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Pteridines and derivatives
• Subclass: Pterins and derivatives
• Intermediate Tree Nodes: Pteroic acids and derivatives - Folic acids and derivatives
• Direct Parent: Folic acids
• Alternative Parents: Glutamic acid and derivatives Acylaminobenzoic acid and derivatives N-acyl-alpha amino acids Hippuric acids Anilides Benzoyl derivatives Aminopyrimidines and derivatives Pyrimidones Pyrazines Dicarboxylic acids and derivatives Vinylogous amides Tertiary carboxylic acid amides Heteroaromatic compounds Secondary carboxylic acid amides Amino acids Carboxylic acids Azacyclic compounds Carbonyl compounds Primary amines Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Folic acid - Glutamic acid or derivatives - Acylaminobenzoic acid or derivatives - Hippuric acid or derivatives - Hippuric acid - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Benzamide - Anilide - Benzoic acid or derivatives - Benzoyl - Aminopyrimidine - Pyrimidone - Pyrimidine - Pyrazine - Monocyclic benzene moiety - Benzenoid - Dicarboxylic acid or derivatives - Vinylogous amide - Heteroaromatic compound - Tertiary carboxylic acid amide - Amino acid - Carboxamide group - Amino acid or derivatives - Secondary carboxylic acid amide - Carboxylic acid derivative - Azacycle - Carboxylic acid - Organic nitrogen compound - Carbonyl group - Organonitrogen compound - Organooxygen compound - Primary amine - Hydrocarbon derivative - Organic oxide - Organic oxygen compound - Amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as folic acids. These are heterocyclic compounds based on the 4-[(pteridin-6-ylmethyl)amino]benzoic acid skeleton conjugated with one or more L-glutamate units.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: DMSO (Slightly, Heated, Sonicated), Methanol (Very Slightly, Heated)
• Sensibilidad: Light sensitive
• Punto de fusión (°C): >196° C (dec.)
• Peso molecular: 469.400 g/mol
• XLogP3: -1.700
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 9
• Exact Mass: 469.135 Da
• Monoisotopic Mass: 469.135 Da
• Topological Polar Surface Area: 217.000 Ų
• Heavy Atom Count: 34
• Formal Charge: 0
• Complexity: 843.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1