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| 2. Yongbing Xu, Yawen Li, Guilin Chen, Minxia Fan, Guangwan Hu, Mingquan Guo. (2023) Screening and identification of potential hypoglycemic and hypolipidemic compounds from aqueous extract of Scutellaria baicalensis Georgi root combing affinity ultrafiltration with multiple drug targets and in silico analysis. PHYTOCHEMICAL ANALYSIS, [PMID:37779216] [10.1002/pca.3285] |
| 3. Chuanyi Gu, Chunru Wang, Wenjie Ma, Yunli Gao, Junyao Li, Qing Jin, Xiaochen Wu. (2023) Drug-Loaded Konjac Glucomannan/Metal–Organic Framework Composite Hydrogels as Antibacterial and Anti-Inflammatory Cell Scaffolds. ACS Applied Materials & Interfaces, [PMID:37632730] [10.1021/acsami.3c06996] |
| 4. Shuting Shi, Yanping Wei, Jinxia Feng, Chuanqin Zhou, Jinsong Zuo, Liangyuan Yao, Jianhua Ding, Kanghua Li, Quanguo He. (2023) Facile and ultrasensitive electrochemical detection of baicalein on bismuth oxide-carboxylated multi-walled carbon nanotube/glassy carbon electrode. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2023.105557] |
| 5. Yufeng Chen, Guobin Xia, Chunfeng Wang, Huawei Wu, Xiaogang Xu, Genxiang Mao, Jiong Wu, Zhenlei Zhao. (2023) Impact of dietary plant flavonoids on 7,8-dihydroxyflavone transepithelial transport in human intestinal Caco-2 cells. Food Science & Nutrition, [PMID:37970375] [10.1002/fsn3.3581] |
| 6. Xin Liu, Wei Niu, Jiamin Liu, Zhao Cui, Jiazheng Li, Zhenhai Zhang, Jianming Ju. (2023) Preparation of β-cyclodextrin and hydroxypropyl-β-cyclodextrin inclusion complexes of baicalein and evaluation of their effects on dextran sulfate sodium-induced acute ulcerative colitis in mice. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.jddst.2023.104714] |
| 7. Liao Zhenkun, Liu Xiaojuan, Zheng Juan, Zhao Chenning, Wang Dengliang, Xu Yang, Sun Chongde. (2023) A multifunctional true caffeoyl coenzyme A O-methyltransferase enzyme participates in the biosynthesis of polymethoxylated flavones in citrus. PLANT PHYSIOLOGY, [PMID:37086474] [10.1093/plphys/kiad249] |
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| 9. Shuoshuo Yang, Guoqi Ni, Mengyang Xia, Hailing Li, Zhonghong Gao. (2022) Mussel inspired multifunctional bovine serum albumin (BSA) coatings loaded with Baicalein (BAI) to enhance osteogenesis and resist oxidative stress for potential application on implant. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:36586655] [10.1016/j.ijbiomac.2022.12.285] |
| 10. Mang-Mang Li, Yi-Ting Chen, Jin-Cang Ruan, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang. (2022) Structure-activity relationship of dietary flavonoids on pancreatic lipase. Current Research in Food Science, [PMID:36618100] [10.1016/j.crfs.2022.100424] |
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| 12. Jingyi Hu, Yiheng Tong, Zhaofeng Shen, Yanan Li, Cheng Cheng, Ryan Au, Feng Xu, Yajun Liu, Lei Zhu, Hong Shen. (2022) Gegen Qinlian decoction ameliorates murine colitis by inhibiting the expansion of Enterobacteriaceae through activating PPAR-γ signaling. BIOMEDICINE & PHARMACOTHERAPY, [PMID:36007273] [10.1016/j.biopha.2022.113571] |
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| 14. Zou Linghui, Zhang Zhongbin, Chen Jinqing, Yang Xu, Li Yuyang, Tang Jing, Du Xiaolu, Tang Ling, Liang Dan, Zhu Xiaoyong, Feng Jianfang, Ding Wenya. (2022) β-Cyclodextrin-Grafted Chitosan Enhances Intestinal Drug Absorption and Its Preliminary Mechanism Exploration. AAPS PHARMSCITECH, 23 (6): (1-11). [PMID:35948815] [10.1208/s12249-022-02380-z] |
| 15. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
| 16. Feng-wei Zhang, Li-yang Peng, Chuan-Jian Shi, Jian-chi Li, Feng-xiang Pang, Wei-ming Fu, Xiao-hua Pan, Jin-fang Zhang. (2022) Baicalein mediates the anti-tumor activity in Osteosarcoma through lncRNA-NEF driven Wnt/β-catenin signaling regulatory axis. Journal of Orthopaedic Translation, [PMID:35330943] [10.1016/j.jot.2021.12.001] |
| 17. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Multispectroscopic and computational evaluation of the binding of flavonoids with bovine serum albumin in the presence of Cu2+. FOOD CHEMISTRY, [PMID:35279499] [10.1016/j.foodchem.2022.132656] |
| 18. Zhao Yan, Hu Jin-Jie, Bai Xiao-Lin, Liu Hao-Peng, Qi Xu-Wei, Liao Xun. (2022) Fast screening of tyrosinase inhibitors from traditional Chinese medicinal plants by ligand fishing in combination with in situ fluorescent assay. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (6): (2265-2273). [PMID:34982177] [10.1007/s00216-021-03864-w] |
| 19. Qingxin Song, Shanxin Peng, Xiaosong Zhu. (2021) Baicalein protects against MPP+/MPTP-induced neurotoxicity by ameliorating oxidative stress in SH-SY5Y cells and mouse model of Parkinson’s disease. NEUROTOXICOLOGY, [PMID:34666128] [10.1016/j.neuro.2021.10.003] |
| 20. Jing Liang, Ke Min, Piao Long, Xuqian Weng, Qun Huang, Bo Chen, Ming Ma. (2021) Selective adsorption of flavonoids on cerium-doped ferroferric oxide magnetic particles. JOURNAL OF CHROMATOGRAPHY A, [PMID:33975082] [10.1016/j.chroma.2021.462189] |
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| 22. Xiaolong Zhang, Qinli Ruan, Yiqian Zhai, Dandan Lu, Chen Li, Yahan Fu, Zihui Zheng, Ying Song, Jun Guo. (2020) Baicalein inhibits non-small-cell lung cancer invasion and metastasis by reducing ezrin tension in inflammation microenvironment. CANCER SCIENCE, 111 (10): (3802-3812). [PMID:32691974] [10.1111/cas.14577] |
| 23. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:32480277] [10.1016/j.saa.2020.118519] |
| 24. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
| 25. Liu Xiaojuan, Zhao Chenning, Gong Qin, Wang Yue, Cao Jinping, Li Xian, Grierson Donald, Sun Chongde. (2020) Characterization of a caffeoyl-CoA O-methyltransferase-like enzyme involved in biosynthesis of polymethoxylated flavones in Citrus reticulata. JOURNAL OF EXPERIMENTAL BOTANY, 71 (10): (3066-3079). [PMID:32182355] [10.1093/jxb/eraa083] |
| 26. Yue Yang, Mingchang Liu, Kai Wang, Yange Yang, Ning Su, Wensheng Huang, Yajun Wu. (2020) Chemical and cytological evaluation of honeybee pollen antioxidant ability. JOURNAL OF FOOD SCIENCE, 85 (3): (824-833). [PMID:32078757] [10.1111/1750-3841.15047] |
| 27. Xiaojuan Liu, Yue Wang, Yezhi Chen, Shuting Xu, Qin Gong, Chenning Zhao, Jinping Cao, Chongde Sun. (2020) Characterization of a Flavonoid 3’/5’/7-O-Methyltransferase from Citrus reticulata and Evaluation of the In Vitro Cytotoxicity of Its Methylated Products. MOLECULES, 25 (4): (858). [PMID:32075249] [10.3390/molecules25040858] |
| 28. Zheng-Hong Liu, Cheng-Xi Yang, Lei Zhang, Cong-Ying Yang, Xiu-Quan Xu. (2019) Baicalein, as a Prooxidant, Triggers Mitochondrial Apoptosis in MCF-7 Human Breast Cancer Cells Through Mobilization of Intracellular Copper and Reactive Oxygen Species Generation. OncoTargets and Therapy, [PMID:31849483] [10.2147/OTT.S222819] |
| 29. Chengyun He, Xiaoling Liu, Zhaojing Jiang, Sheng Geng, Hanjun Ma, Benguo Liu. (2019) Interaction Mechanism of Flavonoids and α-Glucosidase: Experimental and Molecular Modelling Studies. Foods, 8 (9): (355). [PMID:31438605] [10.3390/foods8090355] |
| 30. Chengyun He, Xiaoling Liu, Junliang Sun. (2019) Inhibitory Mechanism of Baicalein Against α-Glucosidase. Natural Product Communications, [PMID:] [10.1177/1934578X19855825] |
| 31. Ni Zeng, Guowen Zhang, Xing Hu, Junhui Pan, Zhisheng Zhou, Deming Gong. (2018) Inhibition mechanism of baicalein and baicalin on xanthine oxidase and their synergistic effect with allopurinol. Journal of Functional Foods, [PMID:] [10.1016/j.jff.2018.10.005] |
| 32. Hui Wang, Wenxi Zhang, Yatao Cheng, Xinyu Zhang, Nannan Xue, Gaorong Wu, Meng Chen, Kang Fang, Wenbo Guo, Fei Zhou, Herong Cui, Tao Ma, Penglong Wang, Haimin Lei. (2018) Design, Synthesis and Biological Evaluation of Ligustrazine-Flavonoid Derivatives as Potential Anti-Tumor Agents. MOLECULES, 23 (9): (2187). [PMID:30200208] [10.3390/molecules23092187] |
| 33. Qing-Hui Wen, Lang-Hong Wang, Xin-An Zeng, De-Bao Niu, Man-Sheng Wang. (2018) Hydroxyl-related differences for three dietary flavonoids as inhibitors of human purine nucleoside phosphorylase. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:29894785] [10.1016/j.ijbiomac.2018.06.045] |
| 34. Dai Chongshan, Tang Shusheng, Wang Yang, Velkov Tony, Xiao Xilong. (2017) Baicalein acts as a nephroprotectant that ameliorates colistin-induced nephrotoxicity by activating the antioxidant defence mechanism of the kidneys and down-regulating the inflammatory response. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 72 (9): (2562-2569). [PMID:28859441] [10.1093/jac/dkx185] |
| 35. Zhengkun Xie, Wang Lu, Lingxi Yang, Gaiping Li, Baoxian Ye. (2017) A voltammetry sensor platform for baicalein and baicalin simultaneous detection in vivo based on Ta2O5-Nb2O5@CTS composite. TALANTA, [PMID:28501181] [10.1016/j.talanta.2017.04.022] |
| 36. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang. (2017) Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:28347593] [10.1016/j.jpba.2017.03.012] |
| 37. Zhengkun Xie, Gaiping Li, Yamin Fu, Mengjiao Sun, Baoxian Ye. (2017) Sensitive, simultaneous determination of chrysin and baicalein based on Ta2O5-chitosan composite modified carbon paste electrode. TALANTA, [PMID:28153298] [10.1016/j.talanta.2017.01.021] |
| 38. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan. (2016) The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum. FOOD CHEMISTRY, [PMID:28159264] [10.1016/j.foodchem.2016.12.001] |
| 39. Hongyan He, Ying Huang, Qi Zhang, Jian-Rong Wang, Xuefeng Mei. (2016) Zwitterionic Cocrystals of Flavonoids and Proline: Solid-State Characterization, Pharmaceutical Properties, and Pharmacokinetic Performance. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.6b00142] |
| 40. Tingxuan Yan, Yue Cheng, Zhixiang Wang, Dechun Huang, Honggang Miao, Yi Zhang. (2015) Preparation and characterization of baicalein powder micronized by the SEDS process. JOURNAL OF SUPERCRITICAL FLUIDS, [PMID:] [10.1016/j.supflu.2015.06.005] |
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| 42. Ting Wu, Xixi Zang, Mengying He, Siyi Pan, Xiaoyun Xu. (2013) Structure–Activity Relationship of Flavonoids on Their Anti-Escherichia coli Activity and Inhibition of DNA Gyrase. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:23926942] [10.1021/jf402222v] |
| 43. Mengmin Liang, Qingwen Hu, Junhao Yu, Heng Zhang, Sijie Liu, Jiangrong Huang, Yi Sun. (2025) Baicalein combined with azoles against fungi in vitro. Frontiers in Microbiology, [PMID:40182279] [10.3389/fmicb.2025.1537229] |
| 44. Zhang Jiaming, Chu Jiangnan, Wu Zhengwei. (2025) Cold atmospheric plasma pretreatment on the extraction of bioactive compounds from Scutellaria baicalensis Georgi. INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1093/ijfood/vvaf041] |
| 45. Li-Feng Li, Meng-Di Wang, Chen-Yang Zhang, Meng-Yao Jin, Hua-Lei Chen, Huan Luo, Tian-Yu Hou, Zhi-Jun Zhang, He Li. (2025) Influence of hydroxyl substitution on the inhibition of flavonoids in advanced glycation end-products formation in glucose-lysine-arginine Maillard reaction models. FOOD RESEARCH INTERNATIONAL, [PMID:40086959] [10.1016/j.foodres.2025.116068] |
| 46. Yuan-yuan Zhai, Qiang Wang, Qi-yao Nong, Mei-yu Gao, Ying Zhang, Qin-wen Xiao, Yuan Tian, Zun-jian Zhang, Feng-guo Xu, Pei Zhang. (2025) Pitavastatin overcomes multi-drug resistance in CRC and NSCLC by targeting the NRP1-ZFX axis. BIOCHEMICAL PHARMACOLOGY, [PMID:40684995] [10.1016/j.bcp.2025.117183] |
| 47. Reng Qiu, Jun Li, Changjun Jiang, Yang Yu, Dandan Li, Xuehan Xie, Yang Lei, Lunguang Yao. (2025) Antibacterial activity of baicalein against Aeromonas hydrophila: in vitro and in vivo evaluation. Frontiers in Microbiology, [PMID:40727559] [10.3389/fmicb.2025.1615029] |
| 48. Simeng Wan, Weiwei Wu, Chunlei Ou, Ying Cao, Xinyun Guo, Hua Liu, Lihua Yao, Hu Su. (2025) Effects of copper treatment on the redox state and secondary metabolism of Scutellaria baicalensis Georgi roots. FUNCTIONAL PLANT BIOLOGY, 52 (10): [PMID:41134099] [10.1071/FP25128] |
| 49. Xin-Mei Xie, Jiao-Jiao Hao, Jun-Zhuo Shi, Yun-Feng Zhou, Peng-Fei Liu, Feng Wang, Xiao-Ming Zheng, Xiu-Ying Yu, Chen-Chen Wang, Yi Yan, Guan-Hua Du, Jun-Ke Song, Yang-Yang He, Xiao-Bin Pang. (2023) Baicalein ameliorates Alzheimer's disease via orchestration of CX3CR1/NF-κB pathway in a triple transgenic mouse model. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:37098656] [10.1016/j.intimp.2023.109994] |
| 50. Meifang Wang, Yinping Dong, Jing Wu, Hongyan Li, Yuanyang Zhang, Saijun Fan, Deguan Li. (2020) Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis. LIFE SCIENCES, [PMID:32950576] [10.1016/j.lfs.2020.118463] |
| 51. Hongjin Chen, Yali Zhang, Wenxin Zhang, Hui Liu, Chuchu Sun, Bing Zhang, Bin Bai, Di Wu, Zhongxiang Xiao, Hazel Lum, Jianmin Zhou, Ruijie Chen, Guang Liang. (2019) Inhibition of myeloid differentiation factor 2 by baicalein protects against acute lung injury. PHYTOMEDICINE, [PMID:31254764] [10.1016/j.phymed.2019.152997] |
| 52. Xinggui Tian, Huaji Jiang, Yuhui Chen, Xiang Ao, Chuan Chen, Wentao Zhang, Feilin He, Xiaoqing Liao, Xiaocheng Jiang, Tao Li, Zhongmin Zhang, Xintao Zhang. (2018) Baicalein Accelerates Tendon-Bone Healing via Activation of Wnt/β-Catenin Signaling Pathway in Rats. Biomed Research International, [PMID:29693006] [10.1155/2018/3849760] |
| 53. Yucheng Zhu, Ruiqi Yang, Zhangchao Deng, Bohua Deng, Kun Zhao, Chen Dai, Gang Wei, YanJiang Wang, Jinshui Zheng, Zhuqing Ren, Wentao Lv, Yingping Xiao, Zhinan Mei, Tongxing Song. (2024) Adipose Tissue-Resident Sphingomonas Paucimobilis Suppresses Adaptive Thermogenesis by Reducing 15-HETE Production and Inhibiting AMPK Pathway. Advanced Science, [PMID:39476363] [10.1002/advs.202310236] |
| 54. Shanshan Guo, Lang Zhou, Xueqi Liu, Li Gao, Yuanyuan Li, Yonggui Wu. (2024) Baicalein alleviates cisplatin-induced acute kidney injury by inhibiting ALOX12-dependent ferroptosis. PHYTOMEDICINE, [PMID:38805781] [10.1016/j.phymed.2024.155757] |
| 55. Wanpeng Zhou, Ruyao Feng, Miaolian Ma, Zhixuan Hu, Tao Yao, Maofeng Zhang. (2025) Natural flavonoids as highly efficient catalyst for rapid H2 generation from NaBH4 methanolysis in cold climates. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2025.115904] |
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| 57. Beibei Zhang, Mengnan Zeng, Ru Wang, Qimei Tie, Ruyi Fan, Xuyuan Zhang, Xiaoke Zheng, Weisheng Feng. (2025) Plantaginis Herba attenuates adriamycin-induced nephropathy: Molecular mechanism insights by integrated transcriptomic and experimental validation. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:39778781] [10.1016/j.jep.2025.119331] |
| 58. Jianting Gao, Yingsai Fan, Chenyue Lu, Xinghua Zhao, Xin He. (2024) The baicalein amorphous solid dispersion to enhance the dissolution and bioavailability and effects on growth performance, meat quality, antioxidant capacity and intestinal flora in Taihang chickens. POULTRY SCIENCE, [PMID:38703758] [10.1016/j.psj.2024.103768] |
| 59. Minyi Huang, Wentao Huang, Renyan Duan, Yingfeng Huang, Yongqiang Xia. (2025) The repairing effect of baicalein on lead induced damage to the gut-liver axis in tadpoles. ENVIRONMENTAL POLLUTION, [PMID:40221113] [10.1016/j.envpol.2025.126232] |
| 60. Kunshan Wang, Yingao Zhai, Zenghui Yu, Xuan Zhang, Suzhen Zhou, Jinbo Fan. (2025) Inhibitory mechanisms of baicalein, genistein, and isoliquiritigenin on α-amylase: Multispectral characterization and molecular simulations reveal binding interactions and conformational changes. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:40555311] [10.1016/j.ijbiomac.2025.145468] |
| 61. Feiran Li, Guangyao Hu, Mengsha Zhou, Liqun Lu. (2025) Baicalein exhibits favorable pharmacokinetics and potent antiviral efficacy against SVCV in carp via NF-κB activation and apoptosis inhibition. AQUACULTURE, [PMID:] [10.1016/j.aquaculture.2025.743408] |
| 62. Yang Shu-Xian, Liu Shu-Sen, Zhi Chen-Xiao, Wei Biao, Cheng Jin-Jun, Zhao Zhi-Gang, Bai Ming-Hua, Wang Bin, Zhu Bin. (2026) Network Pharmacology and Experimental Validation-based Approach to Explore the Effect and Mechanism of Scutellaria baicalensis-Rhodiola rosea Herbal Pair against Ischemic Stroke. World Journal of Traditional Chinese Medicine, [PMID:] [10.4103/wjtcm.wjtcm_55_25] |
| 63. Zengfeng Guo, Ningfeng Zhang, Junshen Huang, Wang Zhang, Yawei Hu, Shaochu Chen, Ming Gong, Jianhua Zhou, Jiancheng Yang, Jiawen Wu. (2026) Baicalein Alleviates Iron Overload-Induced Ferroptosis and Osteogenic Blockade in Osteoblasts by Activating the Nrf2/GPX4 Pathway. BME Frontiers, [PMID:41659821] [10.34133/bmef.0230] |
| 64. Yating Zhang, Jiayi Chen, Shaoying He, Qiuping Tan, Weihong Chi, Leqian Wang, Lexin Ling, Lingyang Fan, Hui Fan. (2026) Bupleurum chinense DC. Ameliorates Depression through Hepatic Lipopolysaccharide-Binding Protein-Associated Inflammation and Monoamine Biosynthesis. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:] [10.1016/j.jep.2026.121484] |
| 65. Changhai Sun, Mengxin Xiao, Biyue Cui, Shiyuan Sun, Shushuang Shen, Shuting Zhang, Xinran Zhang, Liting Mu. (2026) Study on the Correlation Between Anthoxanthins Compounds' Reverse-Phase Chromatographic Behavior and Their Solubility. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2026.145944] |
