The interferon (IFN) pathway is one of the central signaling systems in host antiviral defense, innate immune activation, and immune homeostasis. Its biological essence is not a single ligand triggering a single receptor, but a multilayered network composed of “pathogen sensing - IFN induction ...
Interleukin-29 (IL-29) is a key member of the type III interferon family and is also commonly referred to as interferon lambda 1 (IFN-λ1). IL-29 carries both an “IL-series” designation and a clear interferon-like functional identity.
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