Topic

OxidizingAgents

Techniques for detecting, quantifying and localizing antigens and antibodies — ELISA, Western blotting, immunohistochemistry and flow cytometry. Below are the protocols, FAQs and technical articles in our knowledge base tagged with this topic.

38 resources · protocols, FAQs & articles
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3,3',5,5'-tetra-tert-butyldiphenoquinone (DPQ)

The commercially available organic oxidant 3,3',5,5'-tetra-tert-butyldiphenoquinone (DPQ) can be readily synthesized through the oxidation of the affordable o,o'-di-tert-butylphenol.

Updated Mar 202512 min read✓ Reviewed
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1,3-Diiodo-5,5-Dimethylhydantoin, DIH

1,3-Diiodo-5,5-dimethylhydantoin(DIH) exhibits a reactivity similar to molecular iodine but is easier to manage since it does not sublime as a solid reagent. Additionally, DIH serves as a viable substitute for NIS (N-iodosuccinimide) in the iodination of arenes or enols.

Updated Jan 202512 min read✓ Reviewed
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Dess-Martin periodinane (DMP)

Dess-Martin periodinane (DMP) is a commercially available chemical that decomposes slowly. However, it is sensitive to heat and shock, and exhibits an exothermic reaction when heated above 130 °C.

Updated Feb 202512 min read✓ Reviewed
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2,3-Dichloro-5,6-Dicyanobenzoquinone, DDQ

DDQ (2,3-dichloro-5,6-dicyanobenzoquinone), which exhibits stronger oxidizing properties than 1,4-benzoquinone, serves as a reagent in oxidative coupling and cyclization reactions, as well as in the dehydrogenation of hydroaromatic compounds.

Updated Dec 202412 min read✓ Reviewed
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Dicumyl Peroxide (DCP)

A cascade reaction, catalyzed by copper, results in the formation of quinazolinone through a radical methylation, sp3 C-H amination, and oxidation process.

Updated Nov 202412 min read✓ Reviewed
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Cumene Hydroperoxide (CMHP, CHP)

Cumene hydroperoxide is a stable organic peroxide that can be found commercially with a purity of approximately 80%. When dissolved in benzene at a concentration of 0.2 M, it has a half-life of 29 hours at 145°C.

Updated Oct 202412 min read✓ Reviewed
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Aladdin®Oxidation Reagents

Oxidation reaction, as one of the cornerstones of organic chemistry, its core lies in promoting the release of electrons from target substances, thereby triggering profound changes in chemical properties.

Updated Oct 202412 min read✓ Reviewed
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3-Chloroperoxybenzoic acid, m-CPBA

m-CPBA, a potent oxidizing agent, rivals other peracids in its strength. One notable advantage of 3-chloroperbenzoic acid lies in its handling convenience, being available in powdered form that can be safely stored in refrigerated conditions.

Updated Sep 202412 min read✓ Reviewed
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Chromium Trioxide (CrO3)

Chromium trioxide serves as a potent oxidizing agent, exhibiting insolubility in a majority of organic solvents and a propensity to detonate when in contact with organic compounds and solvents. When dissolved in water, it undergoes transformation into chromic acid and anhydrides, which ...

Updated Sep 202412 min read✓ Reviewed
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Chromium Compounds

Chromium (VI) compounds pose a significant health risk due to their high toxicity, both acutely and chronically, with the potential to cause cancer. In contrast, chromium (III) is vital for human health and exhibits moderate toxicity. When handling chromium (VI) reagents, such as PDC, in their ...

Updated Sep 202412 min read✓ Reviewed
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Tetrabromomethane, CBr4

A facile synthesis of aryl carboxylic acids from aryl ketones by aerobic photooxidation using the inexpensive and easily handled CBr4 as catalyst is applicable to inert compounds under usual photo-irradiation conditions, and appears very attractive for the expansion of the Norrish Type I reaction.

Updated Jul 202412 min read✓ Reviewed
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Cerium Ammonium Nitrate, CAN

Cerium (IV) ammonium nitrate ((NH4)2Ce(NO3)6) is a one-electron oxidizing agent that is used for oxidative addition reactions of electrophilic radicals to alkenes, enabling intermolecular and intramolecular carbon-carbon and carbon-heteroatom bond formation. CAN also oxidizes secondary alcohols ...

Updated Jul 202412 min read✓ Reviewed
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Chloramine-T, N-chloro tosylamide sodium salt

Chloramine-T is a source of electrophilic chlorine. In water, chloramine-T is decomposed to yield hypochlorite, which acts as a disinfectant, and the sulfonamide moiety, which inhibits bacterial grow due to the similarity with para-aminobenzoic acid (a bacterial metabolite). Chloramine-T can ...

Updated Aug 202412 min read✓ Reviewed
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Chloramine-B, N-chlorobenzenesulfonamide sodium salt

The use of chloramine-B as the oxidant and KI or NaBr as the halogen source enables a direct oxidative halogenation of terminal alkynes to provide synthetically valuable 1-iodoalkynes and 1-bromoalkynes in very good yields under mild reaction conditions.

Updated Jul 202412 min read✓ Reviewed
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Tert-Butyl Nitrite (TBN)

The use of tert-butyl nitrite as the co-catalyst in a 2-azaadamantane-N-oxyl(AZADO)- and 9-azanoradamantane-N-oxyl(nor-AZADO)-catalyzed efficient aerobic oxidation of primary alcohols in MeCN instead of the previously reported AcOH provides the corresponding aldehydes selectively. The addition ...

Updated Jun 202412 min read✓ Reviewed
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Sodium Hypochlorite (NaOCl)

Sodium hypochlorite is an inexpensive, strong oxidizing agent, that is used as disinfectant and bleaching agent. It is unstable as a solid, but solutions of up to 40% are commercially available that contain NaOH and NaCl as byproducts of the preparation:

Updated May 202412 min read✓ Reviewed
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N-tert-butylbenzenesulfinimidoyl chloride

A range of unsymmetrical ketones has been prepared in good yields from aldehydes in one simple synthetic operation by addition of organolithium compounds followed by an oxidation using N-tert-butylphenylsulfinimidoyl chloride.

Updated Jun 202412 min read✓ Reviewed
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N-Bromosuccinimide (NBS)

N-Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. The NBS bromination of substrates such as alcohols and amines, followed by elimination of HBr in the ...

Updated May 202412 min read✓ Reviewed
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Burgess reagent

The Burgess reagent, (Methoxycarbonylsulfamoyl)triethylammonium hydroxide is a commercially available compound that has historically found utility as a dehydrating agent. The reagent may also be used to oxidize primary and secondary alcohols to their corresponding aldehydes and ketones in ...

Updated May 202412 min read✓ Reviewed
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Tert-Butyl peroxybenzoate, TBPB

The reaction of tert-butyl peroxybenzoate (TBPB) and ammonia/amines provides the corresponding primary, secondary, and tertiary amides under catalyst- and solvent-free conditions in excellent yields. TBPB is an efficient and highly chemoselective benzoylating reagent for aliphatic amines in the ...

Updated Jun 202412 min read✓ Reviewed
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tert-Butyl hydroperoxide, TBHP

Various aromatic, aliphatic and conjugated alcohols were transformed into the corresponding carboxylic acids and ketones in good yields with aq 70% t-BuOOH in the presence of catalytic amounts of bismuth(III) oxide. This method possesses does not involve cumbersome work-up, exhibits ...

Updated Jun 202412 min read✓ Reviewed
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Benzoyl Peroxide (BPO)

Benzoyl peroxide is a chemical compound with structural formula (C6H5−C(=O)O−)2, often abbreviated as (BzO)2. In terms of its structure, the molecule can be described as two benzoyl (C6H5−C(=O)−, Bz) groups connected by a peroxide (−O−O−). It is a white granular solid with a faint ...

Updated May 202412 min read✓ Reviewed
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Oxidizing Agent-Benzaldehyde

Benzaldehyde(C6H5CHO) is an organic compound consisting of a benzene ring with a formyl substituent. It is among the simplest aromatic aldehydes and one of the most industrially useful.

Updated Apr 202412 min read✓ Reviewed
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Benzophenone

Benzophenone is the organic compound with the formula (C6H5)2CO, generally abbreviated Ph2CO. It is a white solid that is soluble in organic solvents. Benzophenone is a widely used building block in organic chemistry, being the parent diarylketone.

Updated Apr 202412 min read✓ Reviewed

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Techniques often explored alongside immunological experiments.

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