Síndrome EAST (DOID:0060484)

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  1. Nimodipine, Gating inhibitor of Ca v1.1;Gating inhibitor of Ca v1.2;Gating inhibitor of Ca v1.3;Gating inhibitor of Ca v1.4;Activator of CFTR;Antagonist of Mineralocorticoid receptor;Allosteric modulator of P2X4
    CAS: 66085-59-4 Número EC: 266-127-0 Formula: C21H26N2O7 Peso molecular: 418.44
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: N129506
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    Nombre IUPAC
    3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    SMILES
    CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC
    InChIKey
    UIAGMCDKSXEBJQ-UHFFFAOYSA-N
    InChI
    1S/C21H26N2O7/c1-12(2)30-21(25)18-14(4)22-13(3)17(20(24)29-10-9-28-5)19(18)15-7-6-8-16(11-15)23(26)27/h6-8,11-12,19,22H,9-10H2,1-5H3
    Sinónimos
    Nimodipine ap | SPECTRUM1503600 | 2-methoxyethyl propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-d...
  2. Gabapentin, Voltage-gated calcium channel modulator
    CAS: 60142-96-3 Número EC: 262-076-3 Formula: C9H17NO2 Peso molecular: 171.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: G122413
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    Nombre IUPAC
    2-[1-(aminomethyl)cyclohexyl]acetic acid
    SMILES
    C1CCC(CC1)(CC(=O)O)CN
    InChIKey
    UGJMXCAKCUNAIE-UHFFFAOYSA-N
    InChI
    1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)
    Sinónimos
    1-(Aminomethyl)cyclohexaneacetate | 1-(Aminomethyl)cyclohexaneaceticAcid | GABAPENTIN [INN] | GABAPENTIN [JAN] | GABA...
  3. Cytisine
    CAS: 485-35-8 Número EC: 207-616-0 Formula: C11H14N2O Peso molecular: 190.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: C107705
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    Nombre IUPAC
    (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
    SMILES
    C1C2CNCC1C3=CC=CC(=O)N3C2
    InChIKey
    ANJTVLIZGCUXLD-DTWKUNHWSA-N
    InChI
    1S/C11H14N2O/c14-11-3-1-2-10-9-4-8(5-12-6-9)7-13(10)11/h1-3,8-9,12H,4-7H2/t8-,9+/m0/s1
    Sinónimos
    (1R,9S)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one | HB2033 | s2287 | Cytisine ((+)-) | HMS2096N10 | HMS3...
  4. Ro 15-4513, Allosteric modulator of GABA A receptor α1 subunit;Allosteric modulator of GABA A receptor α2 subunit;Allosteric modulator of GABA A receptor α3 subunit;Allosteric modulator of GABA A receptor α4 subunit;Allosteric modulator of GABA A receptor α5 subunit;
    CAS: 91917-65-6 PubChem CID: 5081 Formula: C15H14N6O3 Peso molecular: 326.31
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Fuera de Stock Articulo #: R287802
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    ethyl 8-azido-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
    SMILES
    CCOC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CC(=C3)N=[N+]=[N-])C
    InChIKey
    CFSOJZTUTOQNIA-UHFFFAOYSA-N
    InChI
    1S/C15H14N6O3/c1-3-24-15(23)13-12-7-20(2)14(22)10-6-9(18-19-16)4-5-11(10)21(12)8-17-13/h4-6,8H,3,7H2,1-2H3
    Sinónimos
    BRD-K82823076-001-01-8 | UNII-S5XGL82O5Y | [3H]Ro154513 | [3H]Ro15-4513 | Ro 154513 | Ro 15-4513 | 4H-Imidazo(1,5-a)(...
  5. Hydrocortisone, Agonist of Glucocorticoid receptor;Agonist of Mineralocorticoid receptor
    CAS: 50-23-7 Número EC: 200-020-1 Formula: C21H30O5 Peso molecular: 362.46
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: H110523
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    Nombre IUPAC
    (8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
    SMILES
    CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)CO)O)C)O
    InChIKey
    JYGXADMDTFJGBT-VWUMJDOOSA-N
    InChI
    1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+show more
    Sinónimos
    Cortisporin Otico | Evacort | Barseb HC | Cortenema | Penecort | Permicort | Synacort | Epiderm H | Polcort H | Timoc...
  6. JT010, Activator of TRPA1
    CAS: 917562-33-5 Formula: C16H19ClN2O3S Peso molecular: 354.85
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: J288931
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    Nombre IUPAC
    2-chloro-N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-N-(3-methoxypropyl)acetamide
    SMILES
    COCCCN(C1=NC(=CS1)C2=CC=C(C=C2)OC)C(=O)CCl
    InChIKey
    KZMAWJRXKGLWGS-UHFFFAOYSA-N
    InChI
    1S/C16H19ClN2O3S/c1-21-9-3-8-19(15(20)10-17)16-18-14(11-23-16)12-4-6-13(22-2)7-5-12/h4-7,11H,3,8-10H2,1-2H3
    Sinónimos
    E87822 | EX-A6706 | GTPL10275 | AKOS000745864 | DTXSID401336571 | MS-25543 | JT010 | JT-010 | CID 18524489 | 2-Chloro...
  7. URB597, Inhibitor of Fatty acid amide hydrolase;Inhibitor of Fatty acid amide hydrolase-2;Activator of TRPA1
    CAS: 546141-08-6 Número EC: 637-274-1 PubChem CID: 1383884 Formula: C20H22N2O3 Peso molecular: 338.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: U126873
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    Nombre IUPAC
    [3-(3-carbamoylphenyl)phenyl] N-cyclohexylcarbamate
    SMILES
    C1CCC(CC1)NC(=O)OC2=CC=CC(=C2)C3=CC(=CC=C3)C(=O)N
    InChIKey
    ROFVXGGUISEHAM-UHFFFAOYSA-N
    InChI
    1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24)
    Sinónimos
    CARBAMIC ACID, N-CYCLOHEXYL-, 3'-(AMINOCARBONYL)(1,1'-BIPHENYL)-3-YL ESTER | NCGC00165915-01 | 3'-(3-aminocarbonyl)[1...
  8. MPEP, Allosteric modulator of mGlu 4 receptor;Allosteric modulator of mGlu 5 receptor
    CAS: 96206-92-7 Formula: C14H11N Peso molecular: 193.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: M127959
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    Nombre IUPAC
    2-methyl-6-(2-phenylethynyl)pyridine
    SMILES
    CC1=NC(=CC=C1)C#CC2=CC=CC=C2
    InChIKey
    NEWKHUASLBMWRE-UHFFFAOYSA-N
    InChI
    1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3
    Sinónimos
    NCGC00025044-01 | NCGC00025044-02 | Pyridine, 6-methyl-2-(phenylethynyl)- | 2-Picoline, 6-phenylethynyl- | NCGC000156...
  9. Polygodial, Activator of TRPA1
    CAS: 6754-20-7 Formula: C15H22O2 Peso molecular: 234.33
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    Fuera de Stock Articulo #: P274659
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    Nombre IUPAC
    (1R,4aS,8aS)-5,5,8a-trimethyl-1,4,4a,6,7,8-hexahydronaphthalene-1,2-dicarbaldehyde
    SMILES
    CC1(CCCC2(C1CC=C(C2C=O)C=O)C)C
    InChIKey
    AZJUJOFIHHNCSV-KCQAQPDRSA-N
    InChI
    1S/C15H22O2/c1-14(2)7-4-8-15(3)12(10-17)11(9-16)5-6-13(14)15/h5,9-10,12-13H,4,6-8H2,1-3H3/t12-,13-,15+/m0/s1
    Sinónimos
    1,2-Naphthalenedicarboxaldehyde,1,4,4a,5,6,7,8,8a-octahydro-5,5,8a-trimethyl-, (1R,4aS,8aS)- | A00RAV0W57 | Tadeonal ...
  10. AM 0902, Channel blocker of TRPA1;Inhibitor of TRPA1
    CAS: 1883711-97-4 Formula: C17H15ClN6O2 Peso molecular: 370.79
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: A287071
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    Nombre IUPAC
    1-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-7-methylpurin-6-one
    SMILES
    CN1C=NC2=C1C(=O)N(C=N2)CC3=NC(=NO3)CCC4=CC=C(C=C4)Cl
    InChIKey
    AWJBWNUUODWOKQ-UHFFFAOYSA-N
    InChI
    1S/C17H15ClN6O2/c1-23-9-19-16-15(23)17(25)24(10-20-16)8-14-21-13(22-26-14)7-4-11-2-5-12(18)6-3-11/h2-3,5-6,9-10H,4,7-8H2,1H3
    Sinónimos
    3E4SQ96PCJ | compound 27 [PMID: 26942860] | 1-((3-(4-chlorophenethyl)-1,2,4-oxadiazol-5-yl)methyl)-7-methyl-1H-purin-...
  11. ICA 121431
    CAS: 313254-51-2 Número EC: 809-095-0 Formula: C23H19N3O3S2 Peso molecular: 449.55
    Fuera de Stock Articulo #: I287555
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    Nombre IUPAC
    2,2-diphenyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide
    SMILES
    C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4
    InChIKey
    URSQNPPONHUJDL-UHFFFAOYSA-N
    InChI
    1S/C23H19N3O3S2/c27-22(21(17-7-3-1-4-8-17)18-9-5-2-6-10-18)25-19-11-13-20(14-12-19)31(28,29)26-23-24-15-16-30-23/h1-16,21H,(H,24,26)(H,25,27)
    Sinónimos
    F0012-0842 | Oprea1_750763 | 2,2-DIPHENYL-N-{4-[(1,3-THIAZOL-2-YL)SULFAMOYL]PHENYL}ACETAMIDE | BDBM50118516 | BCP2861...
  12. TB 21007
    CAS: 207306-50-1 PubChem CID: 6918633 Formula: C15H17NO2S3 Peso molecular: 339.5
    Fuera de Stock Articulo #: T288798
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    Nombre IUPAC
    3-(2-hydroxyethylsulfanyl)-6,6-dimethyl-1-(1,3-thiazol-2-yl)-5,7-dihydro-2-benzothiophen-4-one
    SMILES
    CC1(CC2=C(SC(=C2C(=O)C1)SCCO)C3=NC=CS3)C
    InChIKey
    QILRYFCEXLFIDS-UHFFFAOYSA-N
    InChI
    1S/C15H17NO2S3/c1-15(2)7-9-11(10(18)8-15)14(20-6-4-17)21-12(9)13-16-3-5-19-13/h3,5,17H,4,6-8H2,1-2H3
    Sinónimos
    UNII-VL2NQQ83RN | 6,7-Dihydro-3-((2-hydroxyethyl)thio)-6,6-dimethyl-1-(2-thiazolyl)benzo(C)thiophen-4(5H)-one | Benzo...
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