Síndrome de Koolen-de Vries (DOID:0050880)

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  1. PNU 282987, Agonist of nicotinic acetylcholine receptor α7 subunit
    CAS: 711085-63-1 PubChem CID: 9795278 Formula: C14H17ClN2O Peso molecular: 264.75
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: P288832
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    Nombre IUPAC
    N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide
    SMILES
    C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl
    InChIKey
    WECKJONDRAUFDD-ZDUSSCGKSA-N
    InChI
    1S/C14H17ClN2O/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,18)/t13-/m0/s1
    Sinónimos
    AKOS016339643 | PNU-282987 (free base) | PNU282987.HCl | EX-A3238 | PNU282987 | PNU-282987 | HMS3677E04 | MFCD0870311...
  2. MG 624
    CAS: 77257-42-2 PubChem CID: 6433339 Formula: C22H30INO Peso molecular: 451.38
    En Stock Articulo #: M275983
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    Nombre IUPAC
    triethyl-[2-[4-[(E)-2-phenylethenyl]phenoxy]ethyl]azanium;iodide
    SMILES
    CC[N+](CC)(CC)CCOC1=CC=C(C=C1)C=CC2=CC=CC=C2.[I-]
    InChIKey
    RDTKUZXIHMTSJO-UEIGIMKUSA-M
    InChI
    1S/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+;
    Sinónimos
    N,N,N-triethyl-2-[4-[(1E)-2-phenylethenyl]phenoxy]-ethanaminium, monoiodide | NSC706725 | UNII-19B3530KQ6 | SCHEMBL27...
  3. Futibatinib, Fibroblast growth factor receptor inhibitor
    CAS: 1448169-71-8 Formula: C22H22N6O3 Peso molecular: 418.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: T302895
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    Nombre IUPAC
    1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
    SMILES
    COC1=CC(=CC(=C1)C#CC2=NN(C3=NC=NC(=C23)N)C4CCN(C4)C(=O)C=C)OC
    InChIKey
    KEIPNCCJPRMIAX-HNNXBMFYSA-N
    InChI
    1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28)6-5-14-9-16(30-2)11-17(10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2,23,show more
    Sinónimos
    GTPL9786 | DB15149 | FUTIBATINIB [INN] | UNII-4B93MGE4AL | D11725 | 1-((3S)-3-(4-Amino-3-((3,5-dimethoxyphenyl)ethyny...
  4. AS 19, Agonist of 5-HT 7 receptor
    CAS: 1000578-26-6 Formula: C18H25N3 Peso molecular: 283.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Fuera de Stock Articulo #: A286601
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    Nombre IUPAC
    (2S)-N,N-dimethyl-5-(1,3,5-trimethylpyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine
    SMILES
    CC1=C(C(=NN1C)C)C2=CC=CC3=C2CCC(C3)N(C)C
    InChIKey
    BTTOYOKCLDAHHO-HNNXBMFYSA-N
    InChI
    1S/C18H25N3/c1-12-18(13(2)21(5)19-12)17-8-6-7-14-11-15(20(3)4)9-10-16(14)17/h6-8,15H,9-11H2,1-5H3/t15-/m0/s1
    Sinónimos
    (2S)-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine | (2S)-(+)-5-(1,3,5-TRIMET...
  5. R-(+)-Nicotine
    CAS: 25162-00-9 Formula: C10H14N2 Peso molecular: 162.23
    En Stock Articulo #: R333277
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    Nombre IUPAC
    3-[(2R)-1-methylpyrrolidin-2-yl]pyridine
    SMILES
    CN1CCCC1C2=CN=CC=C2
    InChIKey
    SNICXCGAKADSCV-SNVBAGLBSA-N
    InChI
    1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3/t10-/m1/s1
    Sinónimos
    D-Nicotine | (+)-Nicotine | (R)-nicotine
  6. Futibatinib, Fibroblast growth factor receptor inhibitor
    CAS: 1448169-71-8 Formula: C22H22N6O3 Peso molecular: 418.45
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: F421651
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    Identificadores técnicos
    Nombre IUPAC
    1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]pyrazolo[3,4-d]pyrimidin-1-yl]pyrrolidin-1-yl]prop-2-en-1-one
    SMILES
    COC1=CC(=CC(=C1)C#CC2=NN(C3=NC=NC(=C23)N)C4CCN(C4)C(=O)C=C)OC
    InChIKey
    KEIPNCCJPRMIAX-HNNXBMFYSA-N
    InChI
    1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28)6-5-14-9-16(30-2)11-17(10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2,23,show more
    Sinónimos
    GTPL9786 | DB15149 | FUTIBATINIB [INN] | UNII-4B93MGE4AL | D11725 | 1-((3S)-3-(4-Amino-3-((3,5-dimethoxyphenyl)ethyny...
  7. PNU 282987, Agonist of nicotinic acetylcholine receptor α7 subunit
    CAS: 711085-63-1 PubChem CID: 9795278 Formula: C14H17ClN2O Peso molecular: 264.75
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: P425629
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    Identificadores técnicos
    Nombre IUPAC
    N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-4-chlorobenzamide
    SMILES
    C1CN2CCC1C(C2)NC(=O)C3=CC=C(C=C3)Cl
    InChIKey
    WECKJONDRAUFDD-ZDUSSCGKSA-N
    InChI
    1S/C14H17ClN2O/c15-12-3-1-11(2-4-12)14(18)16-13-9-17-7-5-10(13)6-8-17/h1-4,10,13H,5-9H2,(H,16,18)/t13-/m0/s1
    Sinónimos
    AKOS016339643 | PNU-282987 (free base) | PNU282987.HCl | EX-A3238 | PNU282987 | PNU-282987 | HMS3677E04 | MFCD0870311...
  8. AQW051, Agonist of nicotinic acetylcholine receptor α7 subunit
    CAS: 669770-29-0 Formula: C19H22N2O Peso molecular: 294.39
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: A607700
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    Nombre IUPAC
    (3R)-3-[6-(4-methylphenyl)pyridin-3-yl]oxy-1-azabicyclo[2.2.2]octane
    SMILES
    CC1=CC=C(C=C1)C2=NC=C(C=C2)OC3CN4CCC3CC4
    InChIKey
    NPDLTEZXGWRMLQ-IBGZPJMESA-N
    InChI
    1S/C19H22N2O/c1-14-2-4-15(5-3-14)18-7-6-17(12-20-18)22-19-13-21-10-8-16(19)9-11-21/h2-7,12,16,19H,8-11,13H2,1H3/t19-/m0/s1
    Sinónimos
    UNII-JQH481R778 | AQW 051 | (3R)-3-{[6-(4-methylphenyl)pyridin-3-yl]oxy}-1-azabicyclo[2.2.2]octane | SCHEMBL1459285 |...
  9. CP 154,526, Antagonist of CRF 1 receptor
    CAS: 157286-86-7 PubChem CID: 5311055
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: C609564
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    Nombre IUPAC
    N-butyl-N-ethyl-2,5-dimethyl-7-(2,4,6-trimethylphenyl)pyrrolo[3,2-e]pyrimidin-4-amine
    SMILES
    CCCCN(c1nc(C)nc2c1c(C)cn2c1c(C)cc(cc1C)C)CC
    InChIKey
    FHQYJZCJRZHINA-UHFFFAOYSA-N
    InChI
    1S/C23H32N4/c1-8-10-11-26(9-2)22-20-18(6)14-27(23(20)25-19(7)24-22)21-16(4)12-15(3)13-17(21)5/h12-14H,8-11H2,1-7H3
    Sinónimos
    AKOS032946677 | BDBM50058163 | PDSP2_001283 | CP154526 | CP-154526 | N-butyl-N-ethyl-7-mesityl-2,5-dimethyl-7H-pyrrol...
  10. E55888, Agonist of 5-HT 7 receptor
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: E610043
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    Identificadores técnicos
    Nombre IUPAC
    N,N-dimethyl-3-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenethylamine
    SMILES
    CN(CCc1cccc(c1)c1c(C)nn(c1C)C)C
    InChIKey
    MFUWRMRKXKCSPL-UHFFFAOYSA-N
    InChI
    1S/C16H23N3/c1-12-16(13(2)19(5)17-12)15-8-6-7-14(11-15)9-10-18(3)4/h6-8,11H,9-10H2,1-5H3
    Sinónimos
    E55888 | E-55888 | N,N-dimethyl-2-(3-(1,3,5-trimethyl-1H-pyrazol-4-yl)phenyl)ethanamine | N,N-Dimethyl[2-[3-(1,3,5-tr...
  11. PHA-709829, Agonist of nicotinic acetylcholine receptor α7 subunit
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: P612781
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    Identificadores técnicos
    Nombre IUPAC
    N-[(3R,5R)-1-azabicyclo[3.2.1]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide
    SMILES
    O=C(c1ncc2c(c1)cco2)N[C@@H]1C[C@H]2CCN(C1)C2
    InChIKey
    PTGWFYYEAUFEAS-ZYHUDNBSSA-N
    InChI
    1S/C15H17N3O2/c19-15(13-6-11-2-4-20-14(11)7-16-13)17-12-5-10-1-3-18(8-10)9-12/h2,4,6-7,10,12H,1,3,5,8-9H2,(H,17,19)/t10-,12-/m1/s1
    Sinónimos
    PHA-709829|UNII-U4Y54D5P9L|U4Y54D5P9L|PH-709829|CHEMBL403858|FURO(2,3-C)pyridine-5-carboxamide, N-(1R,3R,5R)-1-azabic...
  12. SB656104, Antagonist of 5-HT 7 receptor
    CAS: 446020-51-5 PubChem CID: 10028436
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: S613468
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    Identificadores técnicos
    Nombre IUPAC
    6-[(2R)-2-[2-[4-(4-chlorophenoxy)piperidin-1-yl]ethyl]pyrrolidin-1-yl]sulfonyl-1H-indole
    SMILES
    Clc1ccc(cc1)OC1CCN(CC1)CC[C@H]1CCCN1S(=O)(=O)c1ccc2c(c1)[nH]cc2
    InChIKey
    QEGMGDYIJDZJCI-OAQYLSRUSA-N
    InChI
    1S/C25H30ClN3O3S/c26-20-4-6-22(7-5-20)32-23-11-16-28(17-12-23)15-10-21-2-1-14-29(21)33(30,31)24-8-3-19-9-13-27-25(19)18-24/h3-9,13,18,21,23,27H,1-2,10show more
    Sinónimos
    SB-656104;SB-656104-A
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