Cáncer de ovario Receptor acoplado a proteína G 1 (GPR68)

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  1. Ogerin, Allosteric modulator of GPR68
    CAS: 1309198-71-7 Formula: C17H17N5O Peso molecular: 307.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    Fuera de Stock Articulo #: O288325
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    Nombre IUPAC
    [2-[4-amino-6-(benzylamino)-1,3,5-triazin-2-yl]phenyl]methanol
    SMILES
    C1=CC=C(C=C1)CNC2=NC(=NC(=N2)N)C3=CC=CC=C3CO
    InChIKey
    MDGIEDNDSFMSLP-UHFFFAOYSA-N
    InChI
    1S/C17H17N5O/c18-16-20-15(14-9-5-4-8-13(14)11-23)21-17(22-16)19-10-12-6-2-1-3-7-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
    Sinónimos
    2-[4-Amino-6-[(phenylmethyl)amino]-1,3,5-triazin-2-yl]benzenemethanol
  2. NE 52-QQ57, Antagonist of GPR4
    CAS: 1401728-56-0 Formula: C24H28N6O Peso molecular: 416.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: N421502
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    Nombre IUPAC
    2-[4-[(2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl]phenyl]-5-piperidin-4-yl-1,3,4-oxadiazole
    SMILES
    CCC1=NN2C(=CC(=NC2=C1CC3=CC=C(C=C3)C4=NN=C(O4)C5CCNCC5)C)C
    InChIKey
    HXPQWNPLNIEJOW-UHFFFAOYSA-N
    InChI
    1S/C24H28N6O/c1-4-21-20(22-26-15(2)13-16(3)30(22)29-21)14-17-5-7-18(8-6-17)23-27-28-24(31-23)19-9-11-25-12-10-19/h5-8,13,19,25H,4,9-12,14H2,1-3H3
    Sinónimos
    Pyrazolo[1,​5-​a]​pyrimidine,2-​ethyl-​5,​7-​dimethyl-​3-​[[4-​[5-​(4-​piperidinyl)​-​1,​3,​4-​oxadiazol-​2-​yl]​phen...
  3. NE 52-QQ57, Antagonist of GPR4
    CAS: 1401728-56-0 Formula: C24H28N6O Peso molecular: 416.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: N413659
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    Nombre IUPAC
    2-[4-[(2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl]phenyl]-5-piperidin-4-yl-1,3,4-oxadiazole
    SMILES
    CCC1=NN2C(=CC(=NC2=C1CC3=CC=C(C=C3)C4=NN=C(O4)C5CCNCC5)C)C
    InChIKey
    HXPQWNPLNIEJOW-UHFFFAOYSA-N
    InChI
    1S/C24H28N6O/c1-4-21-20(22-26-15(2)13-16(3)30(22)29-21)14-17-5-7-18(8-6-17)23-27-28-24(31-23)19-9-11-25-12-10-19/h5-8,13,19,25H,4,9-12,14H2,1-3H3
    Sinónimos
    2-(4-((2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl)phenyl)-5-(piperidin-4-yl)-1,3,4-oxadiazole
  4. GPR4 antagonist 3b, Antagonist of GPR4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: G610633
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    Nombre IUPAC
    3-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-8-(piperidin-1-ylmethyl)-6,11-dihydro-5~{H}-benzo[b][1]benzazepine
    SMILES
    CCc1nc2c(n1Cc1ccc3c(c1)CCc1c(N3)ccc(c1)CN1CCCCC1)nc(cc2C)C
    InChIKey
    YFBWGDXTUXTMEM-UHFFFAOYSA-N
    InChI
    1S/C31H37N5/c1-4-29-34-30-21(2)16-22(3)32-31(30)36(29)20-24-9-13-28-26(18-24)11-10-25-17-23(8-12-27(25)33-28)19-35-14-6-5-7-15-35/h8-9,12-13,16-18,33Hshow more
    Sinónimos
    compound 3b
  5. ogerin, Allosteric modulator of GPR68
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: O612468
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    Nombre IUPAC
    [2-[4-amino-6-(benzylamino)-1,3,5-triazin-2-yl]phenyl]methanol
    SMILES
    OCc1ccccc1c1nc(NCc2ccccc2)nc(n1)N
    InChIKey
    MDGIEDNDSFMSLP-UHFFFAOYSA-N
    InChI
    1S/C17H17N5O/c18-16-20-15(14-9-5-4-8-13(14)11-23)21-17(22-16)19-10-12-6-2-1-3-7-12/h1-9,23H,10-11H2,(H3,18,19,20,21,22)
    Sinónimos
    ZINC67740571
  6. NE 52-QQ57, Antagonist of GPR4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: N612205
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    Nombre IUPAC
    2-[4-[(2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl]phenyl]-5-piperidin-4-yl-1,3,4-oxadiazole
    SMILES
    CCc1nn2c(c1Cc1ccc(cc1)c1nnc(o1)C1CCNCC1)nc(cc2C)C
    InChIKey
    HXPQWNPLNIEJOW-UHFFFAOYSA-N
    InChI
    1S/C24H28N6O/c1-4-21-20(22-26-15(2)13-16(3)30(22)29-21)14-17-5-7-18(8-6-17)23-27-28-24(31-23)19-9-11-25-12-10-19/h5-8,13,19,25H,4,9-12,14H2,1-3H3
    Sinónimos
    example 35 [WO2012131633A1] | GPR4 antagonist 13 | NE52-QQ57
  7. Ogerin
    CAS: 1309198-71-7 Formula: C17H17N5O Peso molecular: 307.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
    Fuera de Stock Articulo #: O1494417
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