Receptor de prostaciclina (PTGIR)

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  1. OC000459, Antagonist of DP 2 receptor
    CAS: 851723-84-7 Formula: C21H17FN2O2 Peso molecular: 348.37
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: O127017
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    Nombre IUPAC
    2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid
    SMILES
    CC1=C(C2=C(N1CC(=O)O)C=CC(=C2)F)CC3=NC4=CC=CC=C4C=C3
    InChIKey
    FATGTHLOZSXOBC-UHFFFAOYSA-N
    InChI
    1S/C21H17FN2O2/c1-13-17(11-16-8-6-14-4-2-3-5-19(14)23-16)18-10-15(22)7-9-20(18)24(13)12-21(25)26/h2-10H,11-12H2,1H3,(H,25,26)
    Sinónimos
    TIMAPIPRANT [INN] | 1H-Indole-1-acetic acid, 5-fluoro-2-methyl-3-(2-quinolinylmethyl)- | BCP04237 | [5-Fluoro-2-methy...
  2. Prostaglandin E1, Prostanoid EP2 receptor agonist
    CAS: 745-65-3 Número EC: 212-017-2 Formula: C20H34O5 Peso molecular: 354.48
    Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: P129960
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    7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid
    SMILES
    CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
    InChIKey
    GMVPRGQOIOIIMI-DWKJAMRDSA-N
    InChI
    1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,show more
    Sinónimos
    (-)-Prostaglandin E1 | Prostaglandin E1alpha | AI3-62116 | Prostandin | Prostivas | U 10136 | ALPROSTADIL [VANDF] | H...
  3. DG 041, Antagonist of EP 3 receptor
    CAS: 861238-35-9 Formula: C23H15Cl4FN2O3S2 Peso molecular: 592.32
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: D288137
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    Nombre IUPAC
    (E)-3-[1-[(2,4-dichlorophenyl)methyl]-5-fluoro-3-methylindol-7-yl]-N-(4,5-dichlorothiophen-2-yl)sulfonylprop-2-enamide
    SMILES
    CC1=CN(C2=C(C=C(C=C12)F)C=CC(=O)NS(=O)(=O)C3=CC(=C(S3)Cl)Cl)CC4=C(C=C(C=C4)Cl)Cl
    InChIKey
    BFBTVZNKWXWKNZ-HWKANZROSA-N
    InChI
    1S/C23H15Cl4FN2O3S2/c1-12-10-30(11-14-2-4-15(24)7-18(14)25)22-13(6-16(28)8-17(12)22)3-5-20(31)29-35(32,33)21-9-19(26)23(27)34-21/h2-10H,11H2,1H3,(H,29show more
    Sinónimos
    4,5-dichloro-thiophene-2-sulfonic acid [(E)-3-[1-(2,4-dichlorophenylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]-acryloyl...
  4. Bimatoprost, free acid, Agonist of FP receptor
    CAS: 38344-08-0 Número EC: 806-621-0 Formula: C23H32O5 Peso molecular: 388.5
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: B347977
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    (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-5-phenylpent-1-enyl]cyclopentyl]hept-5-enoic acid
    SMILES
    C1C(C(C(C1O)C=CC(CCC2=CC=CC=C2)O)CC=CCCCC(=O)O)O
    InChIKey
    YFHHIZGZVLHBQZ-KDACTHKWSA-N
    InChI
    1S/C23H32O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,18-22,24-26H,2,7,10-13,16H2,(H,27,28)/bshow more
    Sinónimos
    17-phenyl trinor PGF2a | 5-HEPTENOIC ACID, 7-(3,5-DIHYDROXY-2-(3-HYDROXY-5-PHENYL-1- PENTENYL)CYCLOPENTYL)-, (1R- (1....
  5. Selexipag, Prostanoid IP receptor agonist
    CAS: 475086-01-2 Número EC: 809-991-1 PubChem CID: 9913767 Formula: C26H32N4O4S Peso molecular: 496.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: S288612
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    2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-ylamino]butoxy]-N-methylsulfonylacetamide
    SMILES
    CC(C)N(CCCCOCC(=O)NS(=O)(=O)C)C1=CN=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3
    InChIKey
    QXWZQTURMXZVHJ-UHFFFAOYSA-N
    InChI
    1S/C26H32N4O4S/c1-20(2)30(16-10-11-17-34-19-24(31)29-35(3,32)33)23-18-27-25(21-12-6-4-7-13-21)26(28-23)22-14-8-5-9-15-22/h4-9,12-15,18,20H,10-11,16-17show more
    Sinónimos
    AC-30209 | GTPL7552 | Selexipag | 2-(4-((5,6-diphenyl-2-pyrazinyl)(isopropyl)amino)butoxy)-n-(methylsulfonyl)acetamid...
  6. (R)-Butaprost
    CAS: 69648-38-0 Formula: C24H40O5 Peso molecular: 408.57
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    Fuera de Stock Articulo #: B275459
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    methyl 7-[(1R,2R,3R)-3-hydroxy-2-[(E,4R)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl]heptanoate
    SMILES
    CCCC1(CCC1)C(CC=CC2C(CC(=O)C2CCCCCCC(=O)OC)O)O
    InChIKey
    XRISENIKJUKIHD-LHQZMKCDSA-N
    InChI
    1S/C24H40O5/c1-3-14-24(15-9-16-24)22(27)12-8-11-19-18(20(25)17-21(19)26)10-6-4-5-7-13-23(28)29-2/h8,11,18-19,21-22,26-27H,3-7,9-10,12-17H2,1-2H3/b11-8show more
    Sinónimos
    SCHEMBL17975933 | CAS-69648-38-0 | NCGC00165753-01 | Bay q 4218 | BAY-Q-4218 | Methyl (13E,16R)-11alpha,16-dihydroxy-...
  7. (+)-Fluprostenol, Agonist of FP receptor
    CAS: 54276-17-4 Número EC: 690-686-3 Formula: C23H29F3O6 Peso molecular: 458.47
    Fuera de Stock Articulo #: F287336
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    Nombre IUPAC
    (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid
    SMILES
    C1C(C(C(C1O)C=CC(COC2=CC=CC(=C2)C(F)(F)F)O)CC=CCCCC(=O)O)O
    InChIKey
    WWSWYXNVCBLWNZ-QIZQQNKQSA-N
    InChI
    1S/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-show more
    Sinónimos
    (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-h...
  8. Alprostadil, Prostanoid EP2 receptor agonist
    CAS: 745-65-3 Número EC: 212-017-2 Formula: C20H34O5 Peso molecular: 354.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: A409017
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    Sinónimos
    Prostaglandin-E1, PGE1, Edex, Muse, Liprostin | 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-prost-13-en-1-oic acid
  9. BI-671800, G protein-coupled receptor 44 antagonist
    CAS: 1093108-50-9 Formula: C25H26F3N5O3 Peso molecular: 501.5
    En Stock Articulo #: B412421
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    Nombre IUPAC
    2-[4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]pyrimidin-5-yl]acetic acid
    SMILES
    CN(C)C1=C(C(=NC(=N1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C(F)(F)F)N(C)C)CC(=O)O
    InChIKey
    XEOSTBFUCNZKGS-UHFFFAOYSA-N
    InChI
    1S/C25H26F3N5O3/c1-32(2)22-19(14-21(34)35)23(33(3)4)31-20(30-22)13-15-5-11-18(12-6-15)29-24(36)16-7-9-17(10-8-16)25(26,27)28/h5-12H,13-14H2,1-4H3,(H,2show more
    Sinónimos
    NCGC00345797-02 | AC-30903 | Actimis | BI671800 | BI-671800 | 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-((4-(...
  10. BI-671800, G protein-coupled receptor 44 antagonist
    CAS: 1093108-50-9 Formula: C25H26F3N5O3 Peso molecular: 501.5
    10mM in DMSO
    En Stock Articulo #: B420563
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    Identificadores técnicos
    Nombre IUPAC
    2-[4,6-bis(dimethylamino)-2-[[4-[[4-(trifluoromethyl)benzoyl]amino]phenyl]methyl]pyrimidin-5-yl]acetic acid
    SMILES
    CN(C)C1=C(C(=NC(=N1)CC2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C(F)(F)F)N(C)C)CC(=O)O
    InChIKey
    XEOSTBFUCNZKGS-UHFFFAOYSA-N
    InChI
    1S/C25H26F3N5O3/c1-32(2)22-19(14-21(34)35)23(33(3)4)31-20(30-22)13-15-5-11-18(12-6-15)29-24(36)16-7-9-17(10-8-16)25(26,27)28/h5-12H,13-14H2,1-4H3,(H,2show more
    Sinónimos
    NCGC00345797-02 | AC-30903 | Actimis | BI671800 | BI-671800 | 5-Pyrimidineacetic acid, 4,6-bis(dimethylamino)-2-((4-(...
  11. Butaprost, free acid, Agonist of DP 1 receptor;Agonist of EP 2 receptor;Agonist of EP 3 receptor;Agonist of EP 4 receptor;Agonist of IP receptor;Agonist of TP receptor
    CAS: 433219-55-7 PubChem CID: 25886893 Formula: C23H38O5 Peso molecular: 394.6
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. A solution in methyl acetate
    Fuera de Stock Articulo #: B347295
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    Nombre IUPAC
    7-[(1R,2R,3R)-3-hydroxy-2-[(E,4S)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl]heptanoic acid
    SMILES
    CCCC1(CCC1)C(CC=CC2C(CC(=O)C2CCCCCCC(=O)O)O)O
    InChIKey
    PAYNQYXOKJDXAV-ZHIWTBQHSA-N
    InChI
    1S/C23H38O5/c1-2-13-23(14-8-15-23)21(26)11-7-10-18-17(19(24)16-20(18)25)9-5-3-4-6-12-22(27)28/h7,10,17-18,20-21,25-26H,2-6,8-9,11-16H2,1H3,(H,27,28)/bshow more
  12. Fluprostenol, Agonist of EP 3 receptor;Agonist of FP receptor;Agonist of TP receptor
    CAS: 40666-16-8 Número EC: 200-578-6 Formula: C23H29F3O6 Peso molecular: 458.47
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Solution in ethanol (10 mg/ml)
    En Stock Articulo #: F336171
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    Nombre IUPAC
    (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid
    SMILES
    C1C(C(C(C1O)C=CC(COC2=CC=CC(=C2)C(F)(F)F)O)CC=CCCCC(=O)O)O
    InChIKey
    WWSWYXNVCBLWNZ-QIZQQNKQSA-N
    InChI
    1S/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-show more
    Sinónimos
    (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-h...
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