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Receptor 1 activado por proteasas (F2R)

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  1. ML 354, Antagonist of PAR4
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    ML 354, Antagonist of PAR4
    CAS: 89159-60-4 Número EC: 110-221-5 Formula: C16H14N2O3 Peso molecular: 282.29
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: M286620
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    Precios y tamaños del paquete
    Identificadores técnicos
    Nombre IUPAC
    (1-methyl-5-nitro-3-phenylindol-2-yl)methanol
    SMILES
    CN1C2=C(C=C(C=C2)[N+](=O)[O-])C(=C1CO)C3=CC=CC=C3
    InChIKey
    GNJUKVGDCUKDLF-UHFFFAOYSA-N
    InChI
    1S/C16H14N2O3/c1-17-14-8-7-12(18(20)21)9-13(14)16(15(17)10-19)11-5-3-2-4-6-11/h2-9,19H,10H2,1H3
    Sinónimos
    1-Methyl-5-nitro-3-phenyl-1H-indole-2-methanol | DTXSID90353779 | 1h-indole-2-methanol, 1-methyl-5-nitro-3-phenyl- | ...
  2. ML161
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    ML161
    CAS: 423735-93-7 Número EC: 803-969-5 Formula: C17H17BrN2O2 Peso molecular: 361.23
    ≥98%
    En Stock Articulo #: M129427
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    Identificadores técnicos
    Nombre IUPAC
    2-bromo-N-[3-(butanoylamino)phenyl]benzamide
    SMILES
    CCCC(=O)NC1=CC(=CC=C1)NC(=O)C2=CC=CC=C2Br
    InChIKey
    DFOVLSMXPWPCFH-UHFFFAOYSA-N
    InChI
    1S/C17H17BrN2O2/c1-2-6-16(21)19-12-7-5-8-13(11-12)20-17(22)14-9-3-4-10-15(14)18/h3-5,7-11H,2,6H2,1H3,(H,19,21)(H,20,22)
    Sinónimos
    Cambridge id 5946339 | SR-01000224080 | BRD-K59036917-001-07-6 | MLS002699906 | NCGC00371123-09 | AG-670/40910903 | 2...
  3. BAY 598, Inhibitor of SET and MYND domain containing 2
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    BAY 598, Inhibitor of SET and MYND domain containing 2
    CAS: 1906919-67-2 Formula: C22H20Cl2F2N6O3 Peso molecular: 525.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: B288058
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    Identificadores técnicos
    Nombre IUPAC
    N-[(4S)-2-[N-cyano-N'-[3-(difluoromethoxy)phenyl]carbamimidoyl]-5-(3,4-dichlorophenyl)-3,4-dihydropyrazol-4-yl]-N-ethyl-2-hydroxyacetamide
    SMILES
    CCN(C1CN(N=C1C2=CC(=C(C=C2)Cl)Cl)C(=NC3=CC(=CC=C3)OC(F)F)NC#N)C(=O)CO
    InChIKey
    OTTJIRVZJJGFTK-SFHVURJKSA-N
    InChI
    1S/C22H20Cl2F2N6O3/c1-2-31(19(34)11-33)18-10-32(30-20(18)13-6-7-16(23)17(24)8-13)22(28-12-27)29-14-4-3-5-15(9-14)35-21(25)26/h3-9,18,21,33H,2,10-11H2,show more
    Sinónimos
    N-[(4S)-1-[(Cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-...
  4. AZ 3451, Allosteric modulator of PAR2
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    AZ 3451, Allosteric modulator of PAR2
    CAS: 2100284-59-9 Formula: C30H27BrN4O3 Peso molecular: 571.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    En Stock Articulo #: A286695
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    Identificadores técnicos
    Nombre IUPAC
    2-(6-bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]benzimidazole-5-carboxamide
    SMILES
    CC(C1CCCCC1)N2C3=C(C=C(C=C3)C(=O)NC4=CC=C(C=C4)C#N)N=C2C5=CC6=C(C=C5Br)OCO6
    InChIKey
    FJAOGFGHTPYADT-SFHVURJKSA-N
    InChI
    1S/C30H27BrN4O3/c1-18(20-5-3-2-4-6-20)35-26-12-9-21(30(36)33-22-10-7-19(16-32)8-11-22)13-25(26)34-29(35)23-14-27-28(15-24(23)31)38-17-37-27/h7-15,18,2show more
    Sinónimos
    2-(6-Bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]-1H-benzimidazole-5-carboxamide
  5. AZ 3451, Allosteric modulator of PAR2
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    AZ 3451, Allosteric modulator of PAR2
    CAS: 2100284-59-9 Formula: C30H27BrN4O3 Peso molecular: 571.46
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: A422549
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    Identificadores técnicos
    Nombre IUPAC
    2-(6-bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]benzimidazole-5-carboxamide
    SMILES
    CC(C1CCCCC1)N2C3=C(C=C(C=C3)C(=O)NC4=CC=C(C=C4)C#N)N=C2C5=CC6=C(C=C5Br)OCO6
    InChIKey
    FJAOGFGHTPYADT-SFHVURJKSA-N
    InChI
    1S/C30H27BrN4O3/c1-18(20-5-3-2-4-6-20)35-26-12-9-21(30(36)33-22-10-7-19(16-32)8-11-22)13-25(26)34-29(35)23-14-27-28(15-24(23)31)38-17-37-27/h7-15,18,2show more
    Sinónimos
    2-(6-Bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]-1H-benzimidazole-5-carboxamide
  6. Atopaxar, Proteinase-activated receptor 1 antagonist
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    Atopaxar, Proteinase-activated receptor 1 antagonist
    CAS: 751475-53-3 Formula: C29H38FN3O5 Peso molecular: 527.63
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: A412332
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    Identificadores técnicos
    Nombre IUPAC
    1-(3-tert-butyl-4-methoxy-5-morpholin-4-ylphenyl)-2-(5,6-diethoxy-4-fluoro-3-imino-1H-isoindol-2-yl)ethanone
    SMILES
    CCOC1=C(C(=C2C(=C1)CN(C2=N)CC(=O)C3=CC(=C(C(=C3)N4CCOCC4)OC)C(C)(C)C)F)OCC
    InChIKey
    QWKAUGRRIXBIPO-UHFFFAOYSA-N
    InChI
    1S/C29H38FN3O5/c1-7-37-23-15-19-16-33(28(31)24(19)25(30)27(23)38-8-2)17-22(34)18-13-20(29(3,4)5)26(35-6)21(14-18)32-9-11-36-12-10-32/h13-15,31H,7-12,1show more
    Sinónimos
    Atopaxar (USAN) | NCGC00346938-03 | 1-(3-(tert-butyl)-4-methoxy-5-morpholinophenyl)-2-(5,6-diethoxy-7-fluoro-1-iminoi...
  8. Vorapaxar (MK-5348), Antagonist of PAR1
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    Vorapaxar (MK-5348), Antagonist of PAR1
    CAS: 618385-01-6 Número EC: 612-523-7 PubChem CID: 10077130 Formula: C29H33FN2O4 Peso molecular: 492.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: V408351
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    Sinónimos
    SCH 530348 | Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahyd...
  9. Vorapaxar (MK-5348) - Moligand™, ≥99% CAS No(618385-01-6) by Aladdin Scientific
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    Vorapaxar (MK-5348), Antagonist of PAR1
    CAS: 618385-01-6 Número EC: 612-523-7 PubChem CID: 10077130 Formula: C29H33FN2O4 Peso molecular: 492.58
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    En Stock Articulo #: V413905
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    Identificadores técnicos
    Nombre IUPAC
    ethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1-methyl-3-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-1H-benzo[f][2]bshow more
    SMILES
    CCOC(=O)NC1CCC2C(C1)CC3C(C2C=CC4=NC=C(C=C4)C5=CC(=CC=C5)F)C(OC3=O)C
    InChIKey
    ZBGXUVOIWDMMJE-QHNZEKIYSA-N
    InChI
    1S/C29H33FN2O4/c1-3-35-29(34)32-23-10-11-24-20(14-23)15-26-27(17(2)36-28(26)33)25(24)12-9-22-8-7-19(16-31-22)18-5-4-6-21(30)13-18/h4-9,12-13,16-17,20,show more
    Sinónimos
    AKOS010258941 | Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecah...
  10. no_selection
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    F16357, Agonist of PAR1
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: F610267
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    Identificadores técnicos
    Nombre IUPAC
    (E)-3-(2-chlorophenyl)-1-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one
    SMILES
    Fc1ccc(cc1)CN1CCN(CC1)C(=O)/C=C/c1ccccc1Cl
    InChIKey
    RMDYFILMTQCLCQ-JXMROGBWSA-N
    InChI
    1S/C20H20ClFN2O/c21-19-4-2-1-3-17(19)7-10-20(25)24-13-11-23(12-14-24)15-16-5-8-18(22)9-6-16/h1-10H,11-15H2/b10-7+
    Sinónimos
    Compound 39;Example 1 in WO2007147824
  11. no_selection
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    RWJ-56110, Antagonist of PAR1
    CAS: 252889-88-6 PubChem CID: 9853822
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: R613341
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    Identificadores técnicos
    Nombre IUPAC
    (2S)-4-amino-2-[[(2S)-2-[[1-[(2,6-dichlorophenyl)methyl]-3-(pyrrolidin-1-ylmethyl)indol-6-yl]carbamoylamino]-3-(3,4-difluorophenyl)propanoyl]amino]-N-show more
    SMILES
    NCC[C@@H](C(=O)NCc1ccccc1)NC(=O)[C@H](Cc1ccc(c(c1)F)F)NC(=O)Nc1ccc2c(c1)n(Cc1c(Cl)cccc1Cl)cc2CN1CCCC1
    InChIKey
    SWPAWRHBFNDXEU-BCRBLDSWSA-N
    InChI
    1S/C41H43Cl2F2N7O3/c42-32-9-6-10-33(43)31(32)25-52-24-28(23-51-17-4-5-18-51)30-13-12-29(21-38(30)52)48-41(55)50-37(20-27-11-14-34(44)35(45)19-27)40(54show more
    Sinónimos
    RWJ56110
  12. no_selection
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    UDM-001651, Antagonist of PAR4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Fuera de Stock Articulo #: U614633
    Vista del artículo
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    Identificadores técnicos
    SMILES
    COc1cc(OCc2cccc(c2)OCc2ccccc2)c2c(c1)oc(c2)c1cn2c(n1)sc(n2)OC
    InChIKey
    LFOIDLOIBZFWDO-UHFFFAOYSA-N
    InChI
    1S/C28H23N3O5S/c1-32-21-12-24(35-17-19-9-6-10-20(11-19)34-16-18-7-4-3-5-8-18)22-14-26(36-25(22)13-21)23-15-31-27(29-23)37-28(30-31)33-2/h3-15H,16-17H2show more
    Sinónimos
    compound 54
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  1. Small molecule 21artículos
  2. Peptide 1artículo
  3. Protein 1artículo
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  1. ≥98% 5artículos
  2. ≥98%(HPLC) 3artículos
  3. ≥95% 1artículo
  4. ≥99% 1artículo
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  1. Moligand™ 15artículos
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  2. 500,00 US$ - 1.000,00 US$ 7artículos
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