Apoptosis - Compra dentro de la aplicación Supplier | High Purity

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AZD 5582 dihydrochloride
CAS: 1883545-51-4 PubChem CID: 90489014 Fórmula: C₅₈H₇₈N₈O₈.₂HCl Peso molecular: 1088.21

≥97%(HPLC)

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: A288309
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Nombre IUPAC

(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamshow more

SMILES

CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3C(CC4=CC=CC=C34)OCC#CC#CCOC5CC6=CC=CC=C6C5NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC.Cl.Cl

InChIKey

DAILKFFMJFAUCE-GXSVUDMFSA-N

InChI

1S/C58H78N8O8.2ClH/c1-37(59-3)53(67)61-49(39-21-9-7-10-22-39)57(71)65-31-19-29-45(65)55(69)63-51-43-27-15-13-25-41(43)35-47(51)73-33-17-5-6-18-34-74-4show more

Sinónimos
3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylg...
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UC 112
CAS: 383392-66-3 PubChem CID: 3426979 Fórmula: C₂₂H₂₄N₂O₂ Peso molecular: 348.44

≥98%(HPLC)

● En stock — EE. UU. Articulo #: U288560
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Nombre IUPAC

5-(phenylmethoxymethyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol

SMILES

C1CCN(C1)CC2=CC(=C3C=CC=NC3=C2O)COCC4=CC=CC=C4

InChIKey

LTGLGIQQZXSLLF-UHFFFAOYSA-N

InChI

1S/C22H24N2O2/c25-22-18(14-24-11-4-5-12-24)13-19(20-9-6-10-23-21(20)22)16-26-15-17-7-2-1-3-8-17/h1-3,6-10,13,25H,4-5,11-12,14-16H2

Sinónimos
5-((benzyloxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol | 5-[(Phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-q...
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LCL161, Inhibitor of baculoviral IAP repeat containing 2;Inhibitor of X-linked inhibitor of apoptosis
CAS: 1005342-46-0 Fórmula: C₂₆H₃₃FN₄O₃S Peso molecular: 500.63

Moligand™ ? ≥99%

● En stock — EE. UU. Articulo #: L127178
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Nombre IUPAC

(2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide

SMILES

CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC

InChIKey

UFPFGVNKHCLJJO-SSKFGXFMSA-N

InChI

1S/C26H33FN4O3S/c1-16(28-2)24(33)30-22(17-7-4-3-5-8-17)26(34)31-14-6-9-21(31)25-29-20(15-35-25)23(32)18-10-12-19(27)13-11-18/h10-13,15-17,21-22,28H,3-show more

Sinónimos
LCL 161 [WHO-DD] | (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoet...
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A 410099.1
CAS: 762274-58-8 PubChem CID: 131858992 Fórmula: C₂₇H₄₀N₄O₃·HCl Peso molecular: 505.09

≥98%(HPLC)

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: A287066
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SMILES

CN[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H]2CCCC3=CC=CC=C23)=O)=O)C4CCCCC4)=O)C.Cl

InChIKey

OPCYOBWCDDJCFT-VOSOYEAFSA-N

Sinónimos
N-Methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-[(1R)-1,2,3,4-tetrahydro-1-naphthalenyl]-L-prolinamide hydrochloride
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GDC-0152, Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of baculoviral IAP repeat containing 7;Antagonist of X-linked inhibitor of apoptosis
CAS: 873652-48-3 Fórmula: C₂₅H₃₄N₆O₃S Peso molecular: 498.64

Moligand™ ? ≥98%

● En stock — EE. UU. Articulo #: G129293
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Nombre IUPAC

(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-(4-phenylthiadiazol-5-yl)pyrrolidine-2-carboxamide

SMILES

CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3=C(N=NS3)C4=CC=CC=C4)NC

InChIKey

WZRFLSDVFPIXOV-LRQRDZAKSA-N

InChI

1S/C25H34N6O3S/c1-16(26-2)22(32)27-21(18-12-7-4-8-13-18)25(34)31-15-9-14-19(31)23(33)28-24-20(29-30-35-24)17-10-5-3-6-11-17/h3,5-6,10-11,16,18-19,21,2show more

Sinónimos
AC-32972 | Z2235802113 | A14135 | L-PROLINAMIDE, N-METHYL-L-ALANYL-(2S)-2-CYCLOHEXYLGLYCYL-N-(4-PHENYL-1,2,3-THIADIAZ...
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AT406 (SM-406), Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
CAS: 1071992-99-8 Fórmula: C₃₂H₄₃N₅O₄ Peso molecular: 561.71

Moligand™ ? ≥98%

● En stock — EE. UU. Articulo #: A126412
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Nombre IUPAC

(5S,8S,10aR)-N-benzhydryl-5-[[(2S)-2-(methylamino)propanoyl]amino]-3-(3-methylbutanoyl)-6-oxo-1,2,4,5,8,9,10,10a-octahydropyrrolo[1,2-a][1,5]diazocineshow more

SMILES

CC(C)CC(=O)N1CCC2CCC(N2C(=O)C(C1)NC(=O)C(C)NC)C(=O)NC(C3=CC=CC=C3)C4=CC=CC=C4

InChIKey

LSXUTRRVVSPWDZ-MKKUMYSQSA-N

InChI

1S/C32H43N5O4/c1-21(2)19-28(38)36-18-17-25-15-16-27(37(25)32(41)26(20-36)34-30(39)22(3)33-4)31(40)35-29(23-11-7-5-8-12-23)24-13-9-6-10-14-24/h5-14,21-show more

Sinónimos
Iap inhibitor AT-406 | Debio 1143 | D 1143 | SM 406 | 1071992-99-8 | EX-A104 | GTPL7729 | NSC764757 | NSC-764757 | (5...
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Birinapant, cIAP1/cIAP2 inhibitor
CAS: 1260251-31-7 Fórmula: C₄₂H₅₆F₂N₈O₆ Peso molecular: 806.94

Moligand™ ? ≥98%

● En stock — EE. UU. Articulo #: B129259
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Nombre IUPAC

(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methylshow more

SMILES

CCC(C(=O)N1CC(CC1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)CC6CC(CN6C(=O)C(CC)NC(=O)C(C)NC)O)O)NC(=O)C(C)NC

InChIKey

PKWRMUKBEYJEIX-DXXQBUJASA-N

InChI

1S/C42H56F2N8O6/c1-7-33(49-39(55)21(3)45-5)41(57)51-19-27(53)15-25(51)17-31-29-11-9-23(43)13-35(29)47-37(31)38-32(30-12-10-24(44)14-36(30)48-38)18-26-show more

Sinónimos
2,2-dimethyl-3-hydroxypropyl 2,2-dimethyl-3-hydroxypropionate | NSC767128 | NSC-767128 | D10417 | HY-16591 | (2S)-N-[...
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4-Methylsalicylic acid
CAS: 50-85-1 Número EC: 200-068-3 Fórmula: C₈H₈O₃ Peso molecular: 152.15

Solid ≥99%

● En stock — EE. UU. Articulo #: M111847
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Nombre IUPAC

2-hydroxy-4-methylbenzoic acid

SMILES

CC1=CC(=C(C=C1)C(=O)O)O

InChIKey

NJESAXZANHETJV-UHFFFAOYSA-N

InChI

1S/C8H8O3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)

Sinónimos
2-Hydroxy-4-methylbenzoicacid | gamma-Cresotic acid | HY-78144 | 4-Methyl-2-hydroxybenzoic acid | 4-Methylsalicylate ...
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4-Methylsalicylic acid
CAS: 50-85-1 Número EC: 200-068-3 Fórmula: C₈H₈O₃ Peso molecular: 152.15

10mM in DMSO

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: M424376
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Nombre IUPAC

2-hydroxy-4-methylbenzoic acid

SMILES

CC1=CC(=C(C=C1)C(=O)O)O

InChIKey

NJESAXZANHETJV-UHFFFAOYSA-N

InChI

1S/C8H8O3/c1-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)

Sinónimos
2-Hydroxy-4-methylbenzoicacid | gamma-Cresotic acid | HY-78144 | 4-Methyl-2-hydroxybenzoic acid | 4-Methylsalicylate ...
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AZD5582, Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
CAS: 1258392-53-8 Fórmula: C₅₈H₇₈N₈O₈ Peso molecular: 1015.29

Liquid Moligand™ ? 10mM in Water

◐ .Fabricado bajo pedido · 8–12 semanas Articulo #: A421087
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Nombre IUPAC

(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamshow more

SMILES

CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3C(CC4=CC=CC=C34)OCC#CC#CCOC5CC6=CC=CC=C6C5NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC

InChIKey

WLMCRYCCYXHPQF-ZVMUOSSASA-N

InChI

1S/C58H78N8O8/c1-37(59-3)53(67)61-49(39-21-9-7-10-22-39)57(71)65-31-19-29-45(65)55(69)63-51-43-27-15-13-25-41(43)35-47(51)73-33-17-5-6-18-34-74-48-36-show more

Sinónimos
L-Prolinamide,3,3'-[2,4-hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-�...
Lista de deseos Añadir para comparar
AZD5582, Antagonist of baculoviral IAP repeat containing 2;Antagonist of baculoviral IAP repeat containing 3;Antagonist of X-linked inhibitor of apoptosis
CAS: 1258392-53-8 Fórmula: C₅₈H₇₈N₈O₈ Peso molecular: 1015.29

Moligand™ ? ≥98%

● En stock — EE. UU. Articulo #: A413749
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Nombre IUPAC

(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamino)propanoyl]amino]acetyl]-N-[(1S,2R)-2-[6-[[(1S,2R)-1-[[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-(methylamshow more

SMILES

CC(C(=O)NC(C1CCCCC1)C(=O)N2CCCC2C(=O)NC3C(CC4=CC=CC=C34)OCC#CC#CCOC5CC6=CC=CC=C6C5NC(=O)C7CCCN7C(=O)C(C8CCCCC8)NC(=O)C(C)NC)NC

InChIKey

WLMCRYCCYXHPQF-ZVMUOSSASA-N

InChI

1S/C58H78N8O8/c1-37(59-3)53(67)61-49(39-21-9-7-10-22-39)57(71)65-31-19-29-45(65)55(69)63-51-43-27-15-13-25-41(43)35-47(51)73-33-17-5-6-18-34-74-48-36-show more

Sinónimos
3,3′-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylg...
Lista de deseos Añadir para comparar
Birinapant, cIAP1/cIAP2 inhibitor
CAS: 1260251-31-7 Fórmula: C₄₂H₅₆F₂N₈O₆ Peso molecular: 806.94

Moligand™ ? 10mM in DMSO

● En stock — EE. UU. Articulo #: B421093
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Nombre IUPAC

(2S)-N-[(2S)-1-[(2R,4S)-2-[[6-fluoro-2-[6-fluoro-3-[[(2R,4S)-4-hydroxy-1-[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]butanoyl]pyrrolidin-2-yl]methylshow more

SMILES

CCC(C(=O)N1CC(CC1CC2=C(NC3=C2C=CC(=C3)F)C4=C(C5=C(N4)C=C(C=C5)F)CC6CC(CN6C(=O)C(CC)NC(=O)C(C)NC)O)O)NC(=O)C(C)NC

InChIKey

PKWRMUKBEYJEIX-DXXQBUJASA-N

InChI

1S/C42H56F2N8O6/c1-7-33(49-39(55)21(3)45-5)41(57)51-19-27(53)15-25(51)17-31-29-11-9-23(43)13-35(29)47-37(31)38-32(30-12-10-24(44)14-36(30)48-38)18-26-show more

Sinónimos
2,2-dimethyl-3-hydroxypropyl 2,2-dimethyl-3-hydroxypropionate | NSC767128 | NSC-767128 | D10417 | HY-16591 | (2S)-N-[...

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Preguntas frecuentes

How is the IAP listing put together?

It draws on reported IAP annotations within Apoptosis and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose an IAP modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the IAP entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for IAP compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For IAP work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the IAP compound I need is not listed?

Search by CAS number or SMILES first, since analogs of IAP compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.