Determine the necessary mass, volume, or concentration for preparing a solution.
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detergent for use in cell lysis for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Sodium lauroyl sarcosinate, the sodium salt of an acyl derivative of sarcosine—a natural amino acid occurring in muscles and body tissues—stands out as a valuable component in molecular biology, biochemical, and cell biology research. Derived from a natural fatty acid and the amino acid derivative sarcosine, N-Lauroylsarcosine is a biodegradable anionic surfactant usually synthesized through acylation and neutralization reactions involving lauric acid and sodium sarcosine.This amino acid-type anionic surfactant, also recognized as a fatty acid amide and detergent, exhibits protein denaturant potency and has been integrated into lysing solutions, such as the cornet assay. Its application extends to lysing protoplasts for chromosomal DNA isolation from Streptococcus mutans. Notably, Lauroylsarcosine Sodium Salt, characterized by its ionic detergent properties, is commonly employed for purifying membrane proteins. Additionally, Sodium Lauroyl Sarcosine also plays a crucial role in concentrated salt solutions, facilitating cell lysis in RNA purification protocols and membrane solubilization. Whether it′s breaking down cell structures or facilitating membrane protein purification, this mild surfactant proves valuable in various applications within the realms of biology and biochemistry.
Features and Benefits
Suitable for Molecular Biology, Biochemical and Cell Biology research;Can be used for Protein Purification and Quantification;High purity product for research applications.
| Sonrisas canónicas | CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+] |
|---|---|
| IUPAC Name | sodium;2-[dodecanoyl(methyl)amino]acetate |
| InChIKey | KSAVQLQVUXSOCR-UHFFFAOYSA-M |
| INCHI | 1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1 |
| Isómeros SMILES | CCCCCCCCCCCC(=O)N(C)CC(=O)[O-].[Na+] |
| WGK Alemania | 1 |
| RTECS | MC0598960 |
| Peso molecular | 293.39 |
| Beilstein | 5322974 |
| Reaxy-Rn | 5322974 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5322974&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Clase | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives - N-acyl-alpha amino acids and derivatives |
| Direct Parent | N-acyl-alpha amino acids |
| Alternative Parents | N-acyl amines Tertiary carboxylic acid amides Carboxylic acid salts Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | N-acyl-alpha-amino acid - N-acyl-amine - Tertiary carboxylic acid amide - Carboxamide group - Carboxylic acid salt - Carboxylic acid - Monocarboxylic acid or derivatives - Organic alkali metal salt - Organic zwitterion - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Organic salt - Organic sodium salt - Organic nitrogen compound - Aliphatic acyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as n-acyl-alpha amino acids. These are compounds containing an alpha amino acid which bears an acyl group at its terminal nitrogen atom. |
| External Descriptors | Not available |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jun 06, 2025 | N432003 | |
| Certificate of Analysis | Jun 06, 2025 | N432003 | |
| Certificate of Analysis | Jun 06, 2025 | N432003 | |
| Certificate of Analysis | Jun 06, 2025 | N432003 | |
| Certificate of Analysis | Jun 06, 2025 | N432003 | |
| Certificate of Analysis | Jun 06, 2025 | N432003 |
| Solubilidad | H2O: 100mg/mL, clear to slightly hazy, colorless to faintly yellow |
|---|---|
| Sensibilidad | Moisture sensitive |
| Punto de inflamación (°F) | 512.6 °F |
| Punto de inflamación (°C) | 267 °C |
| Punto de fusión (°C) | 46°C(lit.) |
| Peso molecular | 293.380 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 12 |
| Exact Mass | 293.197 Da |
| Monoisotopic Mass | 293.197 Da |
| Topological Polar Surface Area | 60.400 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 260.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Yuying Zhang, Ying Wang, Xuhui Huang, Jie Zheng, Libo Qi, Baoshang Fu, Lei Qin. (2023) Nutritional value of different parts from sea eel (Astroconger myriaster) determined by untargeted-lipidomic approach. FOOD RESEARCH INTERNATIONAL, [PMID:37803738] [10.1016/j.foodres.2023.113402] |
| 2. Siwenjie Qian, Yanju Chen, Cheng Peng, Xiaofu Wang, Hui Wu, Yang Che, Huanying Wang, Junfeng Xu, Jian Wu. (2022) Dipstick-based rapid nucleic acids purification and CRISPR/Cas12a-mediated isothermal amplification for visual detection of African swine fever virus. TALANTA, [PMID:35149424] [10.1016/j.talanta.2022.123294] |
| 3. Mengle Huang, Yanjun Tang, Peng Zhu. (2021) Effect of sodium N-lauroylsarcosinate/hypromellose on the dispersibility and rheological behavior of carbon black for paper coating application. PROGRESS IN ORGANIC COATINGS, [PMID:] [10.1016/j.porgcoat.2021.106514] |
| 4. Yu Luo, Shenyu Huang, Lie Ma. (2021) A novel detergent-based decellularization combined with carbodiimide crosslinking for improving anti-calcification of bioprosthetic heart valve. Biomedical Materials, 16 (4): (045022). [PMID:33979785] [10.1088/1748-605X/ac0088] |
| 5. Yu-Ying Zhang, Yu-Xi Liu, Zheng Zhou, Da-Yong Zhou, Ming Du, Bei-Wei Zhu, Lei Qin. (2019) Improving Lipidomic Coverage Using UPLC-ESI-Q-TOF-MS for Marine Shellfish by Optimizing the Mobile Phase and Resuspension Solvents. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, [PMID:31293164] [10.1021/acs.jafc.9b01343] |
| 6. Shaoxin Deng, Chengxiang Shi, Xueyan Xu, Hui Zhao, Pingchuan Sun, Tiehong Chen. (2014) Synergy between Polyamine and Anionic Surfactant: A Bioinspired Approach for Ordered Mesoporous Silica. LANGMUIR, [PMID:24571136] [10.1021/la404478b] |
| 7. Liang Wang, Zheng Zhou, Ji Wang, Xu-Song Wang, Da-Yong Zhou, Lei Qin, Xu-Hui Huang. (2024) Mechanism of differentiated and targeted catalysis in complex lipid system under lipase and lipoxygenase mediation. FOOD CHEMISTRY, [PMID:39709915] [10.1016/j.foodchem.2024.142503] |
| 8. Li Zhang, Shanxia Jin, Xiaofeng Guo, Yi Yu, Ping Zhou. (2026) Laser-induced photochemical click reaction enabling on-line tagging and detection of phosphatidylethanolamine by MALDI-mass spectrometry. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2026.116916] |