Trifluoromethanesulfonic anhydride - ≥99% , CAS No.358-23-6

CAS: 358-23-6 Cat. No.: T398957 Peso molecular: 282.14 Beilstein Registry Number: 1813600 Número EC: 206-616-8
Disponible para pedir
GRADE & PURITY ≥99%
Synonyms
EN300-50306 | MFCD00000408 | trifluoromethylsulfonic acid anhydride | trifluoro methanesulfonic anhydride | trifluoromethanesulfonic acid anhydride | trifluoro-methanesulfonic acid anhydride | trifluoromethane-sulfonic acid anhydride | UNII-8W034LHG1U | 1
Storage
Store at 2-8°C,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
10g
T398957-10g
9

16,90US$

29,90US$
Guardar 13,00 US$ (43.48%)
25g
T398957-25g
6

32,90US$

49,90US$
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250g
T398957-250g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

194,90US$

239,90US$
Guardar 45,00 US$ (18.76%)
100g
T398957-100g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

97,90US$

129,90US$
Guardar 32,00 US$ (24.63%)
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 12 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Trifluoromethanesulfonic anhydride, also known as triflic anhydride, is an electrophilic reagent that is an efficient source of trifluoromethyl. It is commonly used in organic chemistry to convert oxygen-containing compounds to triflates and for the electrophilic activation and subsequent conversion of amides, sulfoxides, and phosphorus oxides.

Application:

Catalyst for glycosylation for synthesis of polysaccharides.
Reagent for stereoselective synthesis of mannosazide methyl uronate donors.
Activator for direct glycosylation with anomeric hydroxy sugars.

Specifications

Sinónimos
EN300-50306 | MFCD00000408 | trifluoromethylsulfonic acid anhydride | trifluoro methanesulfonic anhydride | trifluoromethanesulfonic acid anhydride | trifluoro-methanesulfonic acid anhydride | trifluoromethane-sulfonic acid anhydride | UNII-8W034LHG1U | 1
Especificaciones y pureza
≥99%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nota
A fuming, hygroscopic liquid with an irritating odor that reacts violently with water.
Pureza
≥99%
Nombres e identificadores
Sonrisas canónicasC(F)(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F
IUPAC Nametrifluoromethylsulfonyl trifluoromethanesulfonate
InChIKeyWJKHJLXJJJATHN-UHFFFAOYSA-N
INCHI1S/C2F6O5S2/c3-1(4,5)14(9,10)13-15(11,12)2(6,7)8
Isómeros SMILES C(F)(F)(F)S(=O)(=O)OS(=O)(=O)C(F)(F)F
WGK Alemania 3
Número ONU 3265
Grupo de embalaje II
Peso molecular 282.14
Beilstein 1813600
Reaxy-Rn 1813600

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClaseOrganic sulfonic acids and derivatives
SubclassOrganosulfonic acids and derivatives
Intermediate Tree Nodes Alkanesulfonic acids and derivatives - Alkanesulfonic acids
Direct ParentTrifluoromethanesulfonates
Alternative Parents Organosulfonic anhydrides  Sulfonyls  Methanesulfonates  Trihalomethanes  Organofluorides  Organic oxides  Hydrocarbon derivatives  Alkyl fluorides  
Molecular FrameworkAliphatic acyclic compounds
Substituents Trifluoromethanesulfonate - Organosulfonic anhydride - Sulfonyl - Methanesulfonate - Trihalomethane - Organic oxygen compound - Organic oxide - Halomethane - Hydrocarbon derivative - Organosulfur compound - Organofluoride - Organohalogen compound - Alkyl halide - Alkyl fluoride - Aliphatic acyclic compound
DescripciónThis compound belongs to the class of organic compounds known as trifluoromethanesulfonates. These are alkanesulfonic acids, that contain a sulfonate group that is substituted with a trifluoromethyl group.
External Descriptors organosulfonic anhydride
Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

25 results found

Lot NumberCertificate TypeFechaArticulo
A2609496Certificate of AnalysisDec 30, 2025 T398957
A2609498Certificate of AnalysisDec 30, 2025 T398957
A2609512Certificate of AnalysisDec 30, 2025 T398957
A2619631Certificate of AnalysisDec 30, 2025 T398957
A2619632Certificate of AnalysisDec 30, 2025 T398957
A2619633Certificate of AnalysisDec 30, 2025 T398957
A2619637Certificate of AnalysisDec 30, 2025 T398957
A2609489Certificate of AnalysisDec 30, 2025 T398957
K2503226Certificate of AnalysisNov 06, 2025 T398957
H2525142Certificate of AnalysisAug 27, 2025 T398957
H2525143Certificate of AnalysisAug 27, 2025 T398957
G2504052Certificate of AnalysisAug 14, 2025 T398957
G2504054Certificate of AnalysisAug 14, 2025 T398957
G2504055Certificate of AnalysisAug 14, 2025 T398957
D2524053Certificate of AnalysisMay 12, 2025 T398957
D2524054Certificate of AnalysisMay 12, 2025 T398957
D2524055Certificate of AnalysisMay 10, 2025 T398957
D2524056Certificate of AnalysisMay 10, 2025 T398957
B2510640Certificate of AnalysisFeb 15, 2025 T398957
B2510641Certificate of AnalysisFeb 15, 2025 T398957
B2510650Certificate of AnalysisFeb 15, 2025 T398957
B2510639Certificate of AnalysisFeb 15, 2025 T398957
K2217654Certificate of AnalysisAug 19, 2022 T398957
K2217655Certificate of AnalysisAug 19, 2022 T398957
K2217857Certificate of AnalysisAug 19, 2022 T398957

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Propiedades químicas y físicas
SolubilidadMiscible with dichloromethane. Immiscible with hydrocarbons.
SensibilidadHeat sensitive,Hygroscopic
Índice de refracción1.32-1.323
Punto de inflamación (°C)110°C
Punto de ebullición (°C)81~84℃
Punto de fusión (°C)-80°C
Peso molecular282.140 g/mol
XLogP31.600
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count11
Rotatable Bond Count2
Exact Mass281.909 Da
Monoisotopic Mass281.909 Da
Topological Polar Surface Area94.300 Ų
Heavy Atom Count15
Formal Charge0
Complexity370.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Bohong Yu, Yubo Liu, Yingxi Zhang, Linyi Xu, Kai Jin, Andi Sun, Xiuli Zhao, Yongjun Wang, Hongzhuo Liu.  (2023)  An SS31-rapamycin conjugate via RBC hitchhiking for reversing acute kidney injury.  BIOMATERIALS,      [PMID:37939640] [10.1016/j.biomaterials.2023.122383]
2. Zhang Yu, Zheng Jianzhi, Li Xijuan, Wu Ying, Zhang Ke.  (2023)  Stoichiometric Imbalance-promoted Step-growth Polymerization Based on Self-accelerating Three-component Reaction.  CHEMICAL RESEARCH IN CHINESE UNIVERSITIES,  39  (5): (822-828).  [PMID:] [10.1007/s40242-023-3173-3]
3. Tao Sun, Qinjun Chen, Zheng Zhou, Chao Li, Teng Yu, Chen Jiang.  (2023)  A chemiluminescent reporter assisted by in-situ neutrophils for imaging O2− at inflammatory sites.  JOURNAL OF CONTROLLED RELEASE,      [PMID:37100207] [10.1016/j.jconrel.2023.04.035]
4. Chenfang Sun, Guangyuan Feng, Yaru Song, Shanshan Cheng, Shengbin Lei, Wenping Hu.  (2022)  Single Molecule Level and Label-Free Determination of Multibiomarkers with an Organic Field-Effect Transistor Platform in Early Cancer Diagnosis.  ANALYTICAL CHEMISTRY,      [PMID:35446018] [10.1021/acs.analchem.2c00897]
5. Rui Li, Xiaoqing Yin, Shiyi Zhang, Jinchu Yang, Mingqin Zhao.  (2021)  Preparation and pyrolysis of two Amadori analogues as flavor precursors.  JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS,      [PMID:] [10.1016/j.jaap.2021.105357]
6. Yudi Feng, Ke Jin, Jia Guo, Changchun Wang.  (2021)  All-carbocycle hydrocarbon thermosets with high thermal stability and robust mechanical strength for low-k interlayer dielectrics.  Polymer Chemistry,  12  (33): (4812-4821).  [PMID:] [10.1039/D1PY00877C]
7. Hua-Ming Xiao, Shuai Zhao, Ru-Ting Fan, Dilshad Hussain, Xian Wang.  (2021)  Simultaneous determination of short-chain fatty alcohols in aged oil and biodiesels by stable isotope labeling assisted liquid chromatography-mass spectrometry.  TALANTA,      [PMID:33838765] [10.1016/j.talanta.2021.122223]
8. Qingping Xin, Tianyu Liu, Zhao Li, Shaofei Wang, Yifan Li, Zhen Li, Jingyi Ouyang, Zhongyi Jiang, Hong Wu.  (2015)  Mixed matrix membranes composed of sulfonated poly(ether ether ketone) and a sulfonated metal–organic framework for gas separation.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2015.03.060]
9. Zhen Li, Guangwei He, Yuning Zhao, Ying Cao, Hong Wu, Yifan Li, Zhongyi Jiang.  (2014)  Enhanced proton conductivity of proton exchange membranes by incorporating sulfonated metal-organic frameworks.  JOURNAL OF POWER SOURCES,      [PMID:] [10.1016/j.jpowsour.2014.03.123]
10. Yuanqing Fu, Shan Hong, Duo Li, Songbai Liu.  (2013)  Novel Chemical Synthesis of Ginkgolic Acid (13:0) and Evaluation of Its Tyrosinase Inhibitory Activity.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:23701207] [10.1021/jf4012642]
11. Na Li, Jian Gao, Hongzhe Ni, Jialin Zhao, Kuirong Feng, Jingyi Wu, Yijia Lei, Yan Wang, Jiayao Yang, Shiyao Sun, Zhe Wang.  (2024)  Fluorinated Poly(thiophene-based aryl piperidinium) Anion-Exchange Membranes Containing Dual Cation–Dipole Interactions for Alkaline Fuel Cells.  ACS Sustainable Chemistry & Engineering,      [PMID:] [10.1021/acssuschemeng.4c02735]
12. Liu Mu-Han, Sun Wei-Ting, Yang An-Qi, Wang Zhi, Chang Zong, Wang Ai-E, Huang Pei-Qiang.  (2025)  Streamlined synthesis of α-keto-, α-hydroxy- and α,α-difluorophosphonates from amides via electrophilic activation with trifluoromethanesulfonic anhydride.  Science China-Chemistry,      [PMID:] [10.1007/s11426-025-2935-3]
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