Ascorbic acid - analytical standard, Moligand™ , CAS No.50-81-7

CAS: 50-81-7 Cat. No.: A103537 분자식: C₆H₈O₆ 분자량: 176.12 Beilstein Registry Number: 84272 EC 번호: 200-066-2

등급 & 순도 Analytical standard, Moligand™

Synonyms

Ascorbicap|C-Long|Ferrous ascorbate|phosphorus oxichloride|Ceglion|Cenetone|Cetemican|hexamethyl-disiloxane|Ascorb|Cemagyl|Cipca|Planavit C|Secorbate|Vitacee|Ascorbicab|Scorbacid|Cecon|C-Span|Duoscorb|pentakis(chloranyl)-$l^{5}-phosphane|vitamin C|CE-VI-Sol|Viforcit|Vitacimin|Ascorvit|Ce-Mi-Lin|Cetane-Caps TD|Cevitamin|Kyselina askorbova|Roscorbic|Cereon|Proscorbin|3-Oxo-L-gulofuranolactone|Cegiolan|Cescorbat|l-ascorbic acid|Redoxon|Acidum ascorbicum|Concemin|Vitamisin|Ascorteal|Cee-Caps TD|Natrascorb|Acidum ascorbinicum|Cantan|2-amino-butane|Ribena|Stuartinic|Adenex|Vitacin|Celaskon|Ciamin|Vitace|Dora-C-500|Laroscorbine|ALUMINUM POTASSIUM SULFATE [FCC]|Cee-Vite|L-Xyloascorbic acid|Cevalin|Cevi-Bid|Citriscorb|Acido ascorbico|Allercorb|Ce lent|Cemill|Lemascorb|Meri-C|Cevitex|L-ascorbate|Catavin C|Ferancee|Vicelat|Ascoltin|ascorbic acid|Celin|Cetamid|Cetane-Caps TC|Liqui-Cee|L-Lyxoascorbic acid|3-Keto-L-gulofuranolactone|Cevex|Ascorbajen|Ascorbutina|Cergona|Cevimin|Vicomin C|Ascor-B.I.D.|Cebione|Davitamon C|Xitix|Cebicure|Testascorbic|IDO-C|C-Vimin|Natrascorb injectable|Tolfrinic|Viscorin|Colascor|Cortalex|Acide ascorbique|Arco-cee|Cebion|L-(+)-Ascorbic Acid|L(+)-Ascorbic acid|Scorbu-C|Hybrin|USEPA/OPP Pesticide Code: 020503|Ascorin|Cevital|Cewin|C-Quin|L-Threoascorbic acid|Cantaxin|Cevatine|HYDRAZINE, SULPHATE (1:1)|Antiscorbic vitamin|Cebid|Cevitamic acid

Storage

Protected from light,Room temperature,Desiccated

Shipped In

Normal

개요

A calcium channel inhibitor.

사양

동의어

Ascorbicap | C-Long | Ferrous ascorbate | phosphorus oxichloride | Ceglion | Cenetone | Cetemican | hexamethyl-disiloxane | Ascorb | Cemagyl | Cipca | Planavit C | Secorbate | Vitacee | Ascorbicab | Scorbacid | Cecon | C-Span | Duoscorb | pentakis(chloranyl)-$l^{5}-phosphane | vitamin C | CE-VI-Sol | Viforcit | Vitacimin | Ascorvit | Ce-M Show more

사양 및 순도

analytical standard, Moligand™

생화학 및 생리적 메커니즘

It protects cells against the damaging effects of radiation and oxygen radicals,increases the rate of mineralization in osteoblasts,reduces Na+/Ca2+ exchange in cultured astrocytes,modulates cyclic nucleotide levels in B and T cells inhibits apoptosis in

보관 조건

Protected from light,Room temperature,Desiccated

배송

Normal

등급

Moligand™, 분석 표준물질

이름과 식별자

Pubchem Sid

508813562

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508813562

정식 스마일

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

IUPAC Name

(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one

InChIKey

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

INCHI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

이성체 SMILES

C([C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O)O

WGK 독일

1

RTECS

CI7650000

대체 CAS

53262-66-1,6730-29-6,50-81-7,134-03-2 (monosodium salt)

NSC 번호

UN 1648

UN 번호

3

MeSH 용어

Acid, Ascorbic;Acid, L-Ascorbic;Ascorbate, Ferrous;Ascorbate, Magnesium;Ascorbate, Sodium;Ascorbic Acid;Ascorbic Acid, Monosodium Salt;di-L-Ascorbate, Magnesium;Ferrous Ascorbate;Hybrin;L Ascorbic Acid;L-Ascorbic Acid;Magnesium Ascorbate;Magnesium Ascorbi

분자량

176.12

Beilstein

84272

Reaxy-Rn

84272

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=84272&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 분류 Dihydrofurans
      • Subclass Furanones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 분류: Dihydrofurans
• Subclass: Furanones
• Intermediate Tree Nodes: Not available
• Direct Parent: Butenolides
• Alternative Parents: Vinylogous acids Enoate esters Secondary alcohols Lactones Enediols 1,2-diols Oxacyclic compounds Monocarboxylic acids and derivatives Primary alcohols Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: 2-furanone - Vinylogous acid - Alpha,beta-unsaturated carboxylic ester - Enoate ester - 1,2-diol - Carboxylic acid ester - Enediol - Secondary alcohol - Lactone - Carboxylic acid derivative - Oxacycle - Monocarboxylic acid or derivatives - Alcohol - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Organic oxide - Primary alcohol - Organooxygen compound - Aliphatic heteromonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as butenolides. These are dihydrofurans with a carbonyl group at the C2 carbon atom.
• External Descriptors: Water-soluble vitamins

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

ADRA2B Tclin Alpha-2B adrenergic receptor (0 Activities)

Discover Target: ADRA2B

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Lymphoblastoid cell (5959 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

L3MBTL1 Tchem Lethal(3)malignant brain tumor-like protein 1 (14536 Activities)

Discover Target: L3MBTL1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

LMNA Tbio Prelamin-A/C (36751 Activities)

Discover Target: LMNA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GMNN Tbio Geminin (128009 Activities)

Discover Target: GMNN

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

Discover Target: CBX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

관련 대상(비인간)

Plasmodium falciparum (966862 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TGR Thioredoxin glutathione reductase (28579 Activities)

Discover Target: TGR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

작용 메커니즘

화학 및 물리적 특성

• 감도: Light sensitive.
• 특정 회전[α]: 21 ° (C=10, H2O)
• 녹는점(°C): 190-192°C
• 분자량: 176.120 g/mol
• XLogP3: -1.600
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 176.032 Da
• Monoisotopic Mass: 176.032 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 232.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1