Knowledge Base

Frequently Asked Questions: Products, Experiments and Troubleshooting

Answers from Aladdin Scientific's technical team to 290+ questions on antibodies, reagents, purity, storage and experiment troubleshooting.

300 articles
Frequently Asked Questions: Products, Experiments and Troubleshooting

Why Can Biotinylated Peptides Test Negative in Biotin Assays?

A peptide can be biotinylated yet still read negative in a biotin assay. The most common root cause is steric hindrance or conformational occlusion: the biotin is positioned too close to the peptide backbone or becomes shielded by the peptide’s structure/aggregation, so streptavidin/avidin ...

2025-11-05 06:03:05 Updated
Frequently Asked Questions: Products, Experiments and Troubleshooting

What Are the Advantages and Disadvantages of Adding Cholesterol to Liposomes?

Cholesterol is a ubiquitous membrane component in biology. In lipid bilayers it intercalates between phospholipids, tightening packing and modulating fluidity, elasticity, and permeability. In simple terms, it can “fill” packing defects created by imperfectly ordered lipids or by embedded ...

2025-11-05 05:42:10 Updated
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