MAPK/ERK 경로 - 경주 Supplier | High Purity

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(R)-CE3F4
CAS: 1593478-56-8 분자식: C₁₁H₁₀Br₂FNO 분자량: 351.01

≥98%(HPLC)

◐ .주문제작 · 8~12주 항목 #: R287208
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IUPAC 이름

(2R)-5,7-dibromo-6-fluoro-2-methyl-3,4-dihydro-2H-quinoline-1-carbaldehyde

SMILES

CC1CCC2=C(C(=C(C=C2N1C=O)Br)F)Br

InChIKey
ZZLQPWXVZCPUGC-ZCFIWIBFSA-N

InChI

1S/C11H10Br2FNO/c1-6-2-3-7-9(15(6)5-16)4-8(12)11(14)10(7)13/h4-6H,2-3H2,1H3/t6-/m1/s1

Synonyms
(2R)-5,7-Dibromo-6-fluoro-3,4-dihydro-2-methyl-1(2H)-quinolinecarboxaldehyde
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Neoantimycin
CAS: 22862-63-1 분자식: C₃₆H₄₆N₂O₁₂ 분자량: 698.76

≥95%

● 재고 있음 — 미국 항목 #: N329566
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IUPAC 이름

N-(15-benzyl-10-butan-2-yl-14-hydroxy-7,13,13-trimethyl-2,5,9,12-tetraoxo-3-propan-2-yl-1,4,8,11-tetraoxacyclopentadec-6-yl)-3-formamido-2-hydroxybenzshow more

SMILES

CCC(C)C1C(=O)OC(C(C(=O)OC(C(=O)OC(C(C(C(=O)O1)(C)C)O)CC2=CC=CC=C2)C(C)C)NC(=O)C3=C(C(=CC=C3)NC=O)O)C

InChIKey
JIJATTFJYJZEBT-UHFFFAOYSA-N

InChI

1S/C36H46N2O12/c1-8-20(4)29-34(45)47-21(5)26(38-31(42)23-15-12-16-24(27(23)40)37-18-39)32(43)49-28(19(2)3)33(44)48-25(17-22-13-10-9-11-14-22)30(41)36(show more

Synonyms
1,4,8,11-Tetraoxacyclopentadecane, neoantimycin deriv. | 3-(Formylamino)-2-hydroxy-N-[(3S,6S,7R,10S,14R,15R)-14-hydro...
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ML 141
CAS: 71203-35-5 분자식: C₂₂H₂₁N₃O₃S 분자량: 407.49

≥98%

● 재고 있음 — 미국 항목 #: M275404
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IUPAC 이름

4-[3-(4-methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide

SMILES

COC1=CC=C(C=C1)C2CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C4=CC=CC=C4

InChIKey
QBNZBMVRFYREHK-UHFFFAOYSA-N

InChI

1S/C22H21N3O3S/c1-28-19-11-7-17(8-12-19)22-15-21(16-5-3-2-4-6-16)24-25(22)18-9-13-20(14-10-18)29(23,26)27/h2-14,22H,15H2,1H3,(H2,23,26,27)

Synonyms
4-[3-(4-Methoxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]benzenesulfonamide | 4-(5-(4-methoxyphenyl)-3-phenyl-4,5-dihy...
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NSC 23766
CAS: 1177865-17-6 PubChem CID: 16759159 분자식: C₂₄H₃₅N₇·3HCl 분자량: 530.96

≥98%

● 재고 있음 — 미국 항목 #: N129204
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IUPAC 이름

6-N-[2-[5-(diethylamino)pentan-2-ylamino]-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine;trihydrochloride

SMILES

CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C.Cl.Cl.Cl

InChIKey
CPUHORIUXPQCHW-UHFFFAOYSA-N

InChI

1S/C24H35N7.3ClH/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22;;;/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,show more

Synonyms
NSC23766 trihydrochloride | UNM-0000305815 | BN162673 | CCG-265031 | EX-A3156 | NSC23766 3HCl salt | NSC 23766 trihyd...
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Manumycin A
CAS: 52665-74-4 PubChem CID: 6438330 분자식: C₃₁H₃₈N₂O₇ 분자량: 550.64

≥96%

◐ .주문제작 · 8~12주 항목 #: M274901
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IUPAC 이름

(2E,4E,6R)-N-[(1S,5S,6R)-5-hydroxy-5-[(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopenten-1-yl)amino]-7-oxohepta-1,3,5-trienyl]-2-oxo-7-oxabicyclo[4.1.0]hept-3-show more

SMILES

CCCCC(C)C=C(C)C=C(C)C(=O)NC1=CC(C2C(C1=O)O2)(C=CC=CC=CC(=O)NC3=C(CCC3=O)O)O

InChIKey
TWWQHCKLTXDWBD-MVTGTTCWSA-N

InChI

1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,show more

Synonyms
DTXSID401025744 | Manumycin A | LMFA08020185 | NCGC00163464-01 | NCGC00163464-02 | Ucfi-C | 2,4-DECADIENAMIDE, N-(5-H...
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Rhosin hydrochloride
CAS: 1281870-42-5 PubChem CID: 52998412 분자식: C₂₀H₁₉ClN₆O 분자량: 394.86

≥95%

● 재고 있음 — 미국 항목 #: R286684
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IUPAC 이름

(2R)-2-amino-3-(1H-indol-3-yl)-N-[(E)-quinoxalin-6-ylmethylideneamino]propanamide;hydrochloride

SMILES

C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NN=CC3=CC4=NC=CN=C4C=C3)N.Cl

InChIKey
SFRGBDFQSLZYLF-GRYLRVQNSA-N

InChI

1S/C20H18N6O.ClH/c21-16(10-14-12-24-17-4-2-1-3-15(14)17)20(27)26-25-11-13-5-6-18-19(9-13)23-8-7-22-18;/h1-9,11-12,16,24H,10,21H2,(H,26,27);1H/b25-11+;show more

Synonyms
D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride | (R,E)-2-amino-3-(1H-indol-3-yl)-N'-(quinoxalin...
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NSC 23766
CAS: 733767-34-5 분자식: C₂₄H₃₅N₇ 분자량: 421.58

Moligand™ ? ≥95%

◐ .주문제작 · 8~12주 항목 #: N331803
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IUPAC 이름

6-N-[2-[5-(diethylamino)pentan-2-ylamino]-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine

SMILES

CCN(CC)CCCC(C)NC1=NC(=CC(=N1)NC2=CC3=C(C=C(N=C3C=C2)C)N)C

InChIKey
DEFBCZWQLILOJF-UHFFFAOYSA-N

InChI

1S/C24H35N7/c1-6-31(7-2)12-8-9-16(3)27-24-28-18(5)14-23(30-24)29-19-10-11-22-20(15-19)21(25)13-17(4)26-22/h10-11,13-16H,6-9,12H2,1-5H3,(H2,25,26)(H2,2show more

Synonyms
NSC23766 | N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4- pyrimidinyl]-2-methyl-4,6-quinolinediamine | 3-t...
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BMS-214662 hydrochloride
CAS: 195981-08-9 PubChem CID: 44189294 분자식: C₂₅H₂₄ClN₅O₂S₂ 분자량: 526.07

≥98%(HPLC)

◐ .주문제작 · 8~12주 항목 #: B168288
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IUPAC 이름

(3R)-3-benzyl-1-(1H-imidazol-5-ylmethyl)-4-thiophen-2-ylsulfonyl-3,5-dihydro-2H-1,4-benzodiazepine-7-carbonitrile;hydrochloride

SMILES

C1C(N(CC2=C(N1CC3=CN=CN3)C=CC(=C2)C#N)S(=O)(=O)C4=CC=CS4)CC5=CC=CC=C5.Cl

InChIKey
LBPFLNDUCNNGPS-GNAFDRTKSA-N

InChI

1S/C25H23N5O2S2.ClH/c26-13-20-8-9-24-21(11-20)15-30(34(31,32)25-7-4-10-33-25)23(12-19-5-2-1-3-6-19)17-29(24)16-22-14-27-18-28-22;/h1-11,14,18,23H,12,1show more

Synonyms
195981-08-9|BMS-214662 hydrochloride|(R)-1-((1H-Imidazol-4-yl)methyl)-3-benzyl-4-(thiophen-2-ylsulfonyl)-2,3,4,5-tetr...
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Oncrasin 1
CAS: 75629-57-1 분자식: C₁₆H₁₂ClNO 분자량: 269.73

≥98%

● 재고 있음 — 미국 항목 #: O159895
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IUPAC 이름

1-[(4-chlorophenyl)methyl]indole-3-carbaldehyde

SMILES

C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)C=O

InChIKey
ZDRQMXCSSAPUMM-UHFFFAOYSA-N

InChI

1S/C16H12ClNO/c17-14-7-5-12(6-8-14)9-18-10-13(11-19)15-3-1-2-4-16(15)18/h1-8,10-11H,9H2

Synonyms
BP-25398 | ONC-1 | N-4-chlorobenzyl-3-formylindole | FT-0734916 | HY-16662 | 1-[(4-Chlorophenyl)methyl]-1H-indole-3-c...
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XRP44X
CAS: 729605-21-4 PubChem CID: 10339779 분자식: C₂₁H₂₁ClN₄O 분자량: 380.88

≥98%

● 재고 있음 — 미국 항목 #: X342763
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IUPAC 이름

[4-(3-chlorophenyl)piperazin-1-yl]-(5-methyl-2-phenylpyrazol-3-yl)methanone

SMILES

CC1=NN(C(=C1)C(=O)N2CCN(CC2)C3=CC(=CC=C3)Cl)C4=CC=CC=C4

InChIKey
NPHPNBGYPKBDDB-UHFFFAOYSA-N

InChI

1S/C21H21ClN4O/c1-16-14-20(26(23-16)18-7-3-2-4-8-18)21(27)25-12-10-24(11-13-25)19-9-5-6-17(22)15-19/h2-9,14-15H,10-13H2,1H3

Synonyms
Ras-Net (Elk-3) Pathway Inhibitor | Actin Assembly Inhibitor XVI | Ras Activation Inhibitor | Tubulin Polymerization ...
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ZCL 278
CAS: 587841-73-4 PubChem CID: 1791111 분자식: C₂₁H₁₉BrClN₅O₄S₂ 분자량: 584.89

≥95%(HPLC)

● 재고 있음 — 미국 항목 #: Z288200
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IUPAC 이름

2-(4-bromo-2-chlorophenoxy)-N-[[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]carbamothioyl]acetamide

SMILES

CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C

InChIKey
XKZDWYDHEBCGCG-UHFFFAOYSA-N

InChI

1S/C21H19BrClN5O4S2/c1-12-9-13(2)25-20(24-12)28-34(30,31)16-6-4-15(5-7-16)26-21(33)27-19(29)11-32-18-8-3-14(22)10-17(18)23/h3-10H,11H2,1-2H3,(H,24,25,show more

Synonyms
2-(4-브로모-2-클로로페녹시)-N-[[[4-[[(4,6-디메틸-2-피리미디닐)아미노]설포닐]페닐]아미노]티옥소메틸]아세타미드
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Lonafarnib, Protein farnesyltransferase inhibitor
CAS: 193275-84-2 분자식: C₂₇H₃₁Br₂ClN₄O₂ 분자량: 638.82

Moligand™ ? ≥95%

● 재고 있음 — 미국 항목 #: L125407
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IUPAC 이름

4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboshow more

SMILES

C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N

InChIKey
DHMTURDWPRKSOA-RUZDIDTESA-N

InChI

1S/C27H31Br2ClN4O2/c28-20-12-19-2-1-18-13-21(30)14-22(29)24(18)25(26(19)32-15-20)17-5-9-33(10-6-17)23(35)11-16-3-7-34(8-4-16)27(31)36/h12-17,25H,1-11Hshow more

Synonyms
1-Piperidinecarboxamide, 4-(2-(4-((11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo(5,6)cyclohepta(1,2-b)pyridin-11-y...

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자주 묻는 질문

How is the Ras listing put together?

It draws on reported Ras annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.

How do I choose a Ras modulator for my assay?

Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Ras entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.

Which specifications matter most for Ras compounds?

Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Ras work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

What if the Ras compound I need is not listed?

Search by CAS number or SMILES first, since analogs of Ras compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.