Antifolato
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109 produtos
Produtos populares
- Levomefolate calciumSólido ≥95%● Em estoque — EUA Item #: L302964Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- calcium;(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
- SMILES
- CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Ca+2]
- InChIKey
- VWBBRFHSPXRJQD-QNTKWALQSA-L
- InChI
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- Sinónimos
- CALCIUM L-5-METHYLTETRAHYDROFOLATE [DSC] | Rhenium, wire reel, 0.2m, diameter 0.076mm, annealed, 99.97% | BAY86-7660 ...
- Ácido folínico, sal de cálcio penta-hidratadoSólido ≥99%● Em estoque — EUA Item #: F304111Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate;pentahydrate
- SMILES
- C1C(N(C2=C(N1)N=C(NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2]
- InChIKey
- NPPBLUASYYNAIG-ZIGBGYJWSA-L
- InChI
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- Sinónimos
- CALCII FOLINAS [WHO-IP LATIN] | 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N,beta-trimethyl-, (+)-, (Z)-2-b...
- 10-Formyl Folic AcidCAS: 134-05-4 Fórmula: C20H19N7O7 Peso molecular: 469.41● Em estoque — EUA Item #: F334434Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-formylamino]benzoyl]amino]pentanedioic acid
- SMILES
- C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)N(CC2=CN=C3C(=N2)C(=O)NC(=N3)N)C=O
- InChIKey
- UGWUWNVTCLDEOG-ZDUSSCGKSA-N
- InChI
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- Sinónimos
- 10-Formylpteroylglutamic Acid | 10-Formyldihydropteroylglutamate | L-GLUTAMIC ACID, N-(4-(((2-AMINO-3,4-DIHYDRO-4-OXO...
- Pemetrexed, Inhibitor of dihydrofolate reductase;Inhibitor of phosphoribosylglycinamide formyltransferase; phosphoribosylglycinamide synthetase; phosphoribosylaminoimidazole synthetase;Inhibitor of thymidylate synthetaseMoligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — EUA Item #: P125303Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid
- SMILES
- C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)O)C(=O)O
- InChIKey
- WBXPDJSOTKVWSJ-ZDUSSCGKSA-N
- InChI
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- Sinónimos
- GTPL5443 | N-({4-[2-(2-amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]phenyl}carbonyl)-L-glutamic acid...
- Pemetrexed, GAR transformylase inhibitorCAS: 150399-23-8 Fórmula: C20H19N5Na2O6 Peso molecular: 471.37● Em estoque — EUA Item #: P129841Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- disodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
- SMILES
- C1=CC(=CC=C1CCC2=CNC3=C2C(=O)NC(=N3)N)C(=O)NC(CCC(=O)[O-])C(=O)[O-].[Na+].[Na+]
- InChIKey
- NYDXNILOWQXUOF-GXKRWWSZSA-L
- InChI
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- Sinónimos
- CAS-150399-23-8 | Pemetrexed Disodium is known as a Thymidylate synthase inhibitor. | PEMETREXED DISODIUM [USP MONOGR...
- TrimethoprimSólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● Em estoque — EUA Item #: T129928Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N
- InChIKey
- IEDVJHCEMCRBQM-UHFFFAOYSA-N
- InChI
- 1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
- Sinónimos
- 5-(3,4,5-Trimethoxybenzyl)-2,4-diaminopyrimidine | Resprim | Bactoprim | Espectrin | Purbal | Roubal | Streptoplus | ...
- Pemetrexed disodium hydrateCAS: 357166-30-4 Número CE: 604-733-2, 814-356-7 PubChem CID: 135564527 Fórmula: C20H21N5O6·5/2H2O·2Na Peso molecular: 516.42● Em estoque — EUA Item #: P140269Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- tetrasodium;(2S)-2-[[4-[2-(2-amino-4-oxo-3,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate;pentahydrate
- SMILES
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- InChIKey
- ZCTCZKWJFTYNMZ-WKUCUCPSSA-J
- InChI
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- Sinónimos
- UNII-F4GSH45R4C | Pemetrexed accord | (S)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)be...
- Aminopterin Hydrate● Em estoque — EUA Item #: A107171Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
- SMILES
- Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
- InChIKey
- TVZGACDUOSZQKY-LBPRGKRZSA-N
- InChI
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- Sinónimos
- CAS-54-62-6 | Kyselina N-(p-((2,4-diamino-6-pteridinylmethyl)amino)benzoyl)-L(+)-glutamova | (2S)-2-[[4-[[(2,4-Diamin...
- Pralatrexate, Dihydrofolate reductase inhibitorCAS: 146464-95-1 Fórmula: C23H23N7O5 Peso molecular: 477.47Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%● Em estoque — EUA Item #: P125726Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- (2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid
- SMILES
- C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
- InChIKey
- OGSBUKJUDHAQEA-WMCAAGNKSA-N
- InChI
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- Sinónimos
- (2S)-2-({4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]phenyl}formamido)pentanedioic acid | CHEBI:39196 | (2S)-2-((4-...
- 7-Bromo-2,4-diaminoquinazolineCAS: 137553-43-6 Fórmula: C8H7BrN4 Peso molecular: 239.07● Em estoque — EUA Item #: B181364Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 7-bromoquinazoline-2,4-diamine
- SMILES
- C1=CC2=C(C=C1Br)N=C(N=C2N)N
- InChIKey
- YPWBLOIRVSSESG-UHFFFAOYSA-N
- InChI
- 1S/C8H7BrN4/c9-4-1-2-5-6(3-4)12-8(11)13-7(5)10/h1-3H,(H4,10,11,12,13)
- Sinónimos
- DHFR-IN-3 | GS-4262 | 2,4-Quinazolinediamine, 7-bromo- | DTXSID20160236 | J-007040 | SY032047 | 7-Bromo-2,4-diaminoqu...
- Sal de cálcio do ácido folínico hidratadoCAS: 1492-18-8 Fórmula: C20H21CaN7O7 · xH2O Peso molecular: 511.50 (anhydrous basis)Sólido ≥98%● Em estoque — EUA Item #: F107310Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- calcium;(2S)-2-[[4-[(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
- SMILES
- [Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13
- InChIKey
- KVUAALJSMIVURS-ZEDZUCNESA-L
- InChI
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- Sinónimos
- AMPHOTERICINA B (USP-RS) | Calcii folinas | BUDESONIDE COMPONENT OF BREZTRI | Calcifolin | Folinac | Leucovorin calci...
- Diaveridine● Em estoque — EUA Item #: D137262Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 5-[(3,4-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
- SMILES
- COC1=C(C=C(C=C1)CC2=CN=C(N=C2N)N)OC
- InChIKey
- LDBTVAXGKYIFHO-UHFFFAOYSA-N
- InChI
- 1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
- Sinónimos
- CCG-213021 | 2, 5-[(3,4-dimethoxyphenyl)methyl]- | Diaveridina | EN300-7440332 | 5-[(3,4-dimethoxyphenyl)methyl]pyrim...
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Perguntas frequentes
How is the Antifolate listing put together?
It draws on reported Antifolate annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose an Antifolate modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the Antifolate entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for Antifolate compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For Antifolate work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the Antifolate compound I need is not listed?
Search by CAS number or SMILES first, since analogs of Antifolate compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.