HDAC

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  1. NCH 51
    CAS: 848354-66-5 Fórmula: C20H26N2O2S2 Peso molecular: 390.57
    ● Em estoque — EUA Item #: N274711
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    Identificadores técnicos
    Nome IUPAC
    S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate
    SMILES
    CC(C)C(=O)SCCCCCCC(=O)NC1=NC(=CS1)C2=CC=CC=C2
    InChIKey
    MDYDGUOQFUQOGE-UHFFFAOYSA-N
    InChI
    1S/C20H26N2O2S2/c1-15(2)19(24)25-13-9-4-3-8-12-18(23)22-20-21-17(14-26-20)16-10-6-5-7-11-16/h5-7,10-11,14-15H,3-4,8-9,12-13H2,1-2H3,(H,21,22,23)
    Sinónimos
    S-[7-oxo-7-[(4-phenyl-1,3-thiazol-2-yl)amino]heptyl] 2-methylpropanethioate | dibenzo[b,d]furan-4-yl boronic acid | N...
  2. PCI-24781 (Abexinostat), Histone deacetylase inhibitor
    CAS: 783355-60-2 Fórmula: C21H23N3O5 Peso molecular: 397.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    ● Em estoque — EUA Item #: P126975
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    Nome IUPAC
    3-[(dimethylamino)methyl]-N-[2-[4-(hydroxycarbamoyl)phenoxy]ethyl]-1-benzofuran-2-carboxamide
    SMILES
    CN(C)CC1=C(OC2=CC=CC=C21)C(=O)NCCOC3=CC=C(C=C3)C(=O)NO
    InChIKey
    MAUCONCHVWBMHK-UHFFFAOYSA-N
    InChI
    1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
    Sinónimos
    DB12565 | BDBM24622 | ABEXINOSTAT [WHO-DD] | AKOS025149423 | FT-0673532 | UDWXLZLRRVQONG-UHFFFAOYSA-M | CRA-02478 | A...
  3. Nexturastat A, Inhibitor of histone deacetylase 1;Inhibitor of histone deacetylase 6
    CAS: 1403783-31-2 Fórmula: C19H23N3O3 Peso molecular: 341.4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: N349054
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    Nome IUPAC
    4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide
    SMILES
    CCCCN(CC1=CC=C(C=C1)C(=O)NO)C(=O)NC2=CC=CC=C2
    InChIKey
    JZWXMCPARMXZQV-UHFFFAOYSA-N
    InChI
    1S/C19H23N3O3/c1-2-3-13-22(19(24)20-17-7-5-4-6-8-17)14-15-9-11-16(12-10-15)18(23)21-25/h4-12,25H,2-3,13-14H2,1H3,(H,20,24)(H,21,23)
    Sinónimos
    MFCD28099804 | AKOS026750221 | Nexturastat A | Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy- | ...
  4. Marein
    CAS: 535-96-6 PubChem CID: 6441269 Fórmula: C21H22O11 Peso molecular: 450.39
    ● Em estoque — EUA Item #: M342001
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    Nome IUPAC
    (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]prop-2-en-1-one
    SMILES
    O=C(C1=CC=C(O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)C(O)=C1O)/C=C/C3=CC=C(O)C(O)=C3
    InChIKey
    XGEYXJDOVMEJNG-HTFDPZBKSA-N
    InChI
    1S/C21H22O11/c22-8-15-18(28)19(29)20(30)21(32-15)31-14-6-3-10(16(26)17(14)27)11(23)4-1-9-2-5-12(24)13(25)7-9/h1-7,15,18-22,24-30H,8H2/b4-1+/t15-,18-,1show more
    Sinónimos
    (E)-3-(3,4-dihydroxyphenyl)-1-[2,3-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypheny...
  5. Santacruzamate A, Inhibitor of histone deacetylase 2;Inhibitor of histone deacetylase 4;Inhibitor of histone deacetylase 6
    CAS: 1477949-42-0 PubChem CID: 72946782 Fórmula: C15H22N2O3 Peso molecular: 278.35
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    ● Em estoque — EUA Item #: S288868
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    Nome IUPAC
    ethyl N-[4-oxo-4-(2-phenylethylamino)butyl]carbamate
    SMILES
    CCOC(=O)NCCCC(=O)NCCC1=CC=CC=C1
    InChIKey
    HTOYBIILVCHURC-UHFFFAOYSA-N
    InChI
    1S/C15H22N2O3/c1-2-20-15(19)17-11-6-9-14(18)16-12-10-13-7-4-3-5-8-13/h3-5,7-8H,2,6,9-12H2,1H3,(H,16,18)(H,17,19)
    Sinónimos
    ethyl N-{3-[(2-phenylethyl)carbamoyl]propyl}carbamate | HY-N0931 | santacruzamate A | GTPL7916 | NCGC00386359-03 | AK...
  6. Rocilinostato (ACY-1215), Histone deacetylase 6 inhibitor
    CAS: 1316214-52-4 Fórmula: C24H27N5O3 Peso molecular: 433.5
    Sólido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: A124886
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    Nome IUPAC
    N-[7-(hydroxyamino)-7-oxoheptyl]-2-(N-phenylanilino)pyrimidine-5-carboxamide
    SMILES
    C1=CC=C(C=C1)N(C2=CC=CC=C2)C3=NC=C(C=N3)C(=O)NCCCCCCC(=O)NO
    InChIKey
    QGZYDVAGYRLSKP-UHFFFAOYSA-N
    InChI
    1S/C24H27N5O3/c30-22(28-32)15-9-1-2-10-16-25-23(31)19-17-26-24(27-18-19)29(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18,32H,1-2,9-10,15-16H2,(show more
    Sinónimos
    HY-16026 | NCGC00345802-05 | AKOS024259260 | Ricolinostat [USAN] | BDBM50439674 | Ricolinostat (USAN/INN) | Rocilinos...
  7. Romidepsina (FK228, Depsipeptídeo), Histone deacetylase inhibitor
    CAS: 128517-07-7 PubChem CID: 5352062 Fórmula: C24H36N4O6S2 Peso molecular: 540.7
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ● Em estoque — EUA Item #: R125265
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    Nome IUPAC
    (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
    SMILES
    CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C
    InChIKey
    OHRURASPPZQGQM-GCCNXGTGSA-N
    InChI
    1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-show more
    Sinónimos
    Methoxiphenadrinum | Depsipeptide | DEPSIPEPTIDE [WHO-DD] | Romidepsin (FK228) | Chromadax | L-Valine,3-didehydro-2- ...
  8. Butyric acid
    CAS: 107-92-6 Número CE: 203-532-3 Fórmula: C4H8O2 Peso molecular: 88.11
    Líquido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99.5%
    ● Em estoque — EUA Item #: B110442
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    Nome IUPAC
    butanoic acid
    SMILES
    CCCC(=O)O
    InChIKey
    FERIUCNNQQJTOY-UHFFFAOYSA-N
    InChI
    1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
    Sinónimos
    GTPL1059 | butoic acid | Honey robber | propylformic acid | Tox21_300164 | BUTYRIC ACID [WHO-DD] | 1-propanecarboxyla...
  9. Butyric acid
    CAS: 107-92-6 Número CE: 203-532-3 Fórmula: C4H8O2 Peso molecular: 88.11
    Líquido Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    ● Em estoque — EUA Item #: B274612
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    Identificadores técnicos
    Nome IUPAC
    butanoic acid
    SMILES
    CCCC(=O)O
    InChIKey
    FERIUCNNQQJTOY-UHFFFAOYSA-N
    InChI
    1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
    Sinónimos
    GTPL1059 | butoic acid | Honey robber | propylformic acid | Tox21_300164 | BUTYRIC ACID [WHO-DD] | 1-propanecarboxyla...
  10. Butyric acid
    CAS: 107-92-6 Número CE: 203-532-3 Fórmula: C4H8O2 Peso molecular: 88.11
    Líquido AR ? Analytical Reagent grade — high-purity chemicals meeting strict assay limits for lab analysis. Use when accuracy matters and trace impurities could skew results. ≥99%
    ◐ .Sob encomenda · 8–12 semanas Item #: B110440
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    Preços e tamanhos do pacote
    Identificadores técnicos
    Nome IUPAC
    butanoic acid
    SMILES
    CCCC(=O)O
    InChIKey
    FERIUCNNQQJTOY-UHFFFAOYSA-N
    InChI
    1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)
    Sinónimos
    GTPL1059 | butoic acid | Honey robber | propylformic acid | Tox21_300164 | BUTYRIC ACID [WHO-DD] | 1-propanecarboxyla...
  11. Givinostat hydrochloride monohydrate
    CAS: 732302-99-7 Fórmula: C24H27N3O4·HCl·H2O Peso molecular: 475.97
    ● Em estoque — EUA Item #: G129672
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    Nome IUPAC
    [6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate;hydrate;hydrochloride
    SMILES
    CCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO.O.Cl
    InChIKey
    FKGKZBBDJSKCIS-UHFFFAOYSA-N
    InChI
    1S/C24H27N3O4.ClH.H2O/c1-3-27(4-2)15-17-5-7-21-14-18(6-8-20(21)13-17)16-31-24(29)25-22-11-9-19(10-12-22)23(28)26-30;;/h5-14,30H,3-4,15-16H2,1-2H3,(H,2show more
    Sinónimos
    ITF2357,Givinostat, Gavinostat | Givinostat hydrochloride monohydrate; ITF-2357 hydrochloride monohydrate | UNII-6R2...
  12. HNHA
    CAS: 926908-04-5 Fórmula: C17H21NO2S Peso molecular: 303.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    ◐ .Sob encomenda · 8–12 semanas Item #: H274734
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    Nome IUPAC
    N-hydroxy-7-naphthalen-2-ylsulfanylheptanamide
    SMILES
    C1=CC=C2C=C(C=CC2=C1)SCCCCCCC(=O)NO
    InChIKey
    KPNNXHVGOKRBEF-UHFFFAOYSA-N
    InChI
    1S/C17H21NO2S/c19-17(18-20)9-3-1-2-6-12-21-16-11-10-14-7-4-5-8-15(14)13-16/h4-5,7-8,10-11,13,20H,1-3,6,9,12H2,(H,18,19)
    Sinónimos
    BMB90804 | GTPL7911 | HY-118672 | CCG-208687 | CHEBI:94741 | N-hydroxy-7-(naphthalen-2-ylthio)heptanamide | AS-66085 ...
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Perguntas frequentes

How is the HDAC listing put together?
It draws on reported HDAC annotations within Cell Cycle/DNA Damage and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a HDAC modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the HDAC entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for HDAC compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For HDAC work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the HDAC compound I need is not listed?
Search by CAS number or SMILES first, since analogs of HDAC compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.

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